Tom Mikkelsen
Tom Mikkelsen
Ontario Brain Institute
Verified email at braininstitute.ca
Title
Cited by
Cited by
Year
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network
Nature 455 (7216), 1061, 2008
55262008
The somatic genomic landscape of glioblastoma
CW Brennan, RGW Verhaak, A McKenna, B Campos, H Noushmehr, ...
Cell 155 (2), 462-477, 2013
31502013
Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group
PY Wen, DR Macdonald, DA Reardon, TF Cloughesy, AG Sorensen, ...
Journal of clinical oncology 28 (11), 1963-1972, 2010
28552010
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
HS Friedman, MD Prados, PY Wen, T Mikkelsen, D Schiff, LE Abrey, ...
J clin oncol 27 (28), 4733-4740, 2009
23902009
Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas
Cancer Genome Atlas Research Network
New England Journal of Medicine 372 (26), 2481-2498, 2015
17492015
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ...
Cancer cell 22 (4), 425-437, 2012
13882012
The immune landscape of cancer
V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ...
Immunity 48 (4), 812-830. e14, 2018
12552018
Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma
M Ceccarelli, FP Barthel, TM Malta, TS Sabedot, SR Salama, BA Murray, ...
Cell 164 (3), 550-563, 2016
11482016
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
9822018
Oncogenic signaling pathways in the cancer genome atlas
F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ...
Cell 173 (2), 321-337. e10, 2018
8602018
Clonal expansion of p53 mutant cells is associated with brain tumour progression
D Sidransky, T Mikkelsen, K Schwechheimer, ML Rosenblum, ...
Nature 355 (6363), 846-847, 1992
8091992
Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer
KA Hoadley, C Yau, T Hinoue, DM Wolf, AJ Lazar, E Drill, R Shen, ...
Cell 173 (2), 291-304. e6, 2018
7682018
An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics
J Liu, T Lichtenberg, KA Hoadley, LM Poisson, AJ Lazar, AD Cherniack, ...
Cell 173 (2), 400-416. e11, 2018
7642018
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
L Sun, AM Hui, Q Su, A Vortmeyer, Y Kotliarov, S Pastorino, A Passaniti, ...
Cancer cell 9 (4), 287-300, 2006
7552006
Tumor evolution of glioma-intrinsic gene expression subtypes associates with immunological changes in the microenvironment
Q Wang, B Hu, X Hu, H Kim, M Squatrito, L Scarpace, AC deCarvalho, ...
Cancer cell 32 (1), 42-56. e6, 2017
5942017
Transforming fusions of FGFR and TACC genes in human glioblastoma
D Singh, JM Chan, P Zoppoli, F Niola, R Sullivan, A Castano, EM Liu, ...
Science 337 (6099), 1231-1235, 2012
5922012
Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme
DA Reardon, KL Fink, T Mikkelsen, TF Cloughesy, A O'Neill, S Plotkin, ...
Journal of clinical oncology 26 (34), 5610-5617, 2008
5212008
The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline
ME Linskey, DW Andrews, AL Asher, SH Burri, D Kondziolka, ...
Journal of neuro-oncology 96 (1), 45-68, 2010
5152010
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response
NJ Szerlip, A Pedraza, D Chakravarty, M Azim, J McGuire, Y Fang, ...
Proceedings of the National Academy of Sciences 109 (8), 3041-3046, 2012
4802012
New brain tumor entities emerge from molecular classification of CNS-PNETs
D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ...
Cell 164 (5), 1060-1072, 2016
4612016
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Articles 1–20