Yu Yu
Yu Yu
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Thiosemicarbazones from the old to new: iron chelators that are more than just ribonucleotide reductase inhibitors
Y Yu, DS Kalinowski, Z Kovacevic, AR Siafakas, PJ Jansson, C Stefani, ...
Journal of medicinal chemistry 52 (17), 5271-5294, 2009
Tuning cell cycle regulation with an iron key
Y Yu, Z Kovacevic, DR Richardson
Cell cycle 6 (16), 1982-1994, 2007
Design, synthesis, and characterization of novel iron chelators: Structure− activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl …
DS Kalinowski, Y Yu, PC Sharpe, M Islam, YT Liao, DB Lovejoy, N Kumar, ...
Journal of medicinal chemistry 50 (15), 3716-3729, 2007
Chelators at the cancer coalface: desferrioxamine to Triapine and beyond
Y Yu, J Wong, DB Lovejoy, DS Kalinowski, DR Richardson
Clinical Cancer Research 12 (23), 6876-6883, 2006
Iron chelators for the treatment of cancer
Y Yu, E Gutierrez, Z Kovacevic, F Saletta, P Obeidy, Y Suryo Rahmanto, ...
Current medicinal chemistry 19 (17), 2689-2702, 2012
Inhibition of spleen tyrosine kinase potentiates paclitaxel-induced cytotoxicity in ovarian cancer cells by stabilizing microtubules
Y Yu, S Gaillard, JM Phillip, TC Huang, SM Pinto, NG Tessarollo, Z Zhang, ...
Cancer cell 28 (1), 82-96, 2015
Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti‐tumour efficacy
Y Yu, YS Rahmanto, DR Richardson
British journal of pharmacology 165 (1), 148-166, 2012
Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1
Y Yu, DR Richardson
Journal of Biological Chemistry 286 (17), 15413-15427, 2011
Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B
WCJ Singleton, KT McInnes, MA Cater, WR Winnall, R McKirdy, Y Yu, ...
Journal of Biological Chemistry 285 (35), 27111-27121, 2010
The medicinal chemistry of novel iron chelators for the treatment of cancer
Z Kovacevic, D S Kalinowski, D B Lovejoy, Y Yu, Y Suryo Rahmanto, ...
Current topics in medicinal chemistry 11 (5), 483-499, 2011
Therapeutic inducers of apoptosis in ovarian cancer
M Binju, MA Amaya-Padilla, G Wan, H Gunosewoyo, Y Suryo Rahmanto, ...
Cancers 11 (11), 1786, 2019
Ovarian cancer stem cells and their role in drug resistance
Z Pieterse, MA Amaya-Padilla, T Singomat, M Binju, BD Madjid, Y Yu, ...
The International Journal of Biochemistry & Cell Biology 106, 117-126, 2019
Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming
Y Suryo Rahmanto, W Shen, X Shi, X Chen, Y Yu, ZC Yu, T Miyamoto, ...
Nature communications 11 (1), 2717, 2020
The potent and novel thiosemicarbazone chelators di-2-pyridylketone-4, 4-dimethyl-3-thiosemicarbazone and 2-benzoylpyridine-4, 4-dimethyl-3-thiosemicarbazone affect crucial …
Y Yu, YS Rahmanto, CL Hawkins, DR Richardson
Molecular pharmacology 79 (6), 921-931, 2011
Drug repositioning of mevalonate pathway inhibitors as antitumor agents for ovarian cancer
Y Kobayashi, H Kashima, YS Rahmanto, K Banno, Y Yu, Y Matoba, ...
Oncotarget 8 (42), 72147, 2017
Mechanisms underlying acquired platinum resistance in high grade serous ovarian cancer-a mini review
M Binju, MA Padilla, T Singomat, P Kaur, YS Rahmanto, PA Cohen, Y Yu
Biochimica et Biophysica Acta (BBA)-General Subjects 1863 (2), 371-378, 2019
Melanotransferrin: search for a function
YS Rahmanto, S Bal, KH Loh, Y Yu, DR Richardson
Biochimica et Biophysica Acta (BBA)-General Subjects 1820 (3), 237-243, 2012
Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4, 4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α …
AM Merlot, NH Shafie, Y Yu, V Richardson, PJ Jansson, S Sahni, ...
Biochemical Pharmacology 109, 27-47, 2016
Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway
Y Yu, Y Suryo Rahmanto, MH Lee, PH Wu, JM Phillip, CH Huang, ...
Oncogene 37 (28), 3778-3789, 2018
Proteome-wide tyrosine phosphorylation analysis reveals dysregulated signaling pathways in ovarian tumors*[S]
G Song, L Chen, B Zhang, Q Song, Y Yu, C Moore, TL Wang, IM Shih, ...
Molecular & Cellular Proteomics 18 (3), 448-460, 2019
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