Deep resequencing reveals excess rare recent variants consistent with explosive population growth A Coventry, LM Bull-Otterson, X Liu, AG Clark, TJ Maxwell, J Crosby, ... Nature communications 1 (1), 131, 2010 | 269 | 2010 |
Oligogenic heterozygosity in individuals with high-functioning autism spectrum disorders CP Schaaf, A Sabo, Y Sakai, J Crosby, D Muzny, A Hawes, L Lewis, ... Human molecular genetics 20 (17), 3366-3375, 2011 | 187 | 2011 |
Connexin 43 inhibition sensitizes chemoresistant glioblastoma cells to temozolomide SF Murphy, RT Varghese, S Lamouille, S Guo, KJ Pridham, P Kanabur, ... Cancer research 76 (1), 139-149, 2016 | 149 | 2016 |
Estimating the number of genetic mutations (hits) required for carcinogenesis based on the distribution of somatic mutations R Anandakrishnan, RT Varghese, NA Kinney, HR Garner PLoS computational biology 15 (3), e1006881, 2019 | 62 | 2019 |
Survival kinase genes present prognostic significance in glioblastoma RT Varghese, Y Liang, T Guan, CT Franck, DF Kelly, Z Sheng Oncotarget 7 (15), 20140, 2016 | 62 | 2016 |
PIK3CB/p110β is a selective survival factor for glioblastoma KJ Pridham, L Le, S Guo, RT Varghese, S Algino, Y Liang, R Fajardin, ... Neuro-oncology 20 (4), 494-505, 2018 | 49 | 2018 |
Casein kinase 1 epsilon regulates glioblastoma cell survival RT Varghese, S Young, L Pham, Y Liang, KJ Pridham, S Guo, S Murphy, ... Scientific reports 8 (1), 13621, 2018 | 30 | 2018 |
An integrated approach to biomarker discovery reveals gene signatures highly predictive of cancer progression KL Sheng, L Kang, KJ Pridham, LE Dunkenberger, Z Sheng, ... Scientific reports 10 (1), 21246, 2020 | 27 | 2020 |
Differentiating between cancer and normal tissue samples using multi-hit combinations of genetic mutations S Dash, NA Kinney, RT Varghese, HR Garner, W Feng, ... Scientific reports 9 (1), 1005, 2019 | 24 | 2019 |
The role of class IA phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunits in glioblastoma KJ Pridham, RT Varghese, Z Sheng Frontiers in oncology 7, 312, 2017 | 24 | 2017 |
Connexin 43 confers chemoresistance through activating PI3K KJ Pridham, F Shah, KR Hutchings, KL Sheng, S Guo, M Liu, P Kanabur, ... Oncogenesis 11 (1), 2, 2022 | 13 | 2022 |
High-depth, high-accuracy microsatellite genotyping enables precision lung cancer risk classification KR Velmurugan, RT Varghese, NC Fonville, HR Garner Oncogene 36 (46), 6383-6390, 2017 | 13 | 2017 |
Functional blockade of small GTPase RAN inhibits glioblastoma cell viability KL Sheng, KJ Pridham, Z Sheng, S Lamouille, RT Varghese Frontiers in Oncology 8, 662, 2019 | 11 | 2019 |
CAGm: a repository of germline microsatellite variations in the 1000 genomes project N Kinney, K Titus-Glover, JD Wren, RT Varghese, P Michalak, H Liao, ... Nucleic acids research 47 (D1), D39-D45, 2019 | 11 | 2019 |
ZDHHC3 as a Risk and Mortality Marker for Breast Cancer in African American Women N Kinney, RT Varghese, R Anandakrishnan, HRS Garner Cancer informatics 16, 1176935117746644, 2017 | 10 | 2017 |
Abundance of ethnically biased microsatellites in human gene regions N Kinney, L Kang, L Eckstrand, A Pulenthiran, P Samuel, ... PLoS One 14 (12), e0225216, 2019 | 6 | 2019 |
DNA sequencing of anatomy lab cadavers to provide hands-on precision medicine introduction to medical students R Anandakrishnan, TL Carpenetti, P Samuel, B Wasko, C Johnson, ... BMC Medical Education 20, 1-14, 2020 | 4 | 2020 |
Identifying carcinogenic multi-hit combinations using weighted set cover algorithm S Dash, N Kinney, R Varghese, H Garner, W Feng, R Anandakrishnan ICPP PhD Forum, 2018 | 1 | 2018 |
Cancer signatures, methods of generating cancer signatures, and uses thereof RT Varghese, K Sheng US Patent App. 17/786,373, 2023 | | 2023 |
A novel glioblastoma prognostic assay using droplet digital polymerase chain reaction. P Beck, KR Hutchings, C Grant, K Sheng, JA Morales, R Varghese, ... Journal of Clinical Oncology 40 (16_suppl), e14026-e14026, 2022 | | 2022 |