| Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer MKH Hong, G Macintyre, DC Wedge, P Van Loo, K Patel, S Lunke, ... Nature communications 6 (1), 6605, 2015 | 395 | 2015 |
| Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells L Pirola, A Balcerczyk, RW Tothill, I Haviv, A Kaspi, S Lunke, M Ziemann, ... Genome research 21 (10), 1601-1615, 2011 | 241 | 2011 |
| Circulating tumour cells from patients with colorectal cancer have cancer stem cell hallmarks in ex vivo culture F Grillet, E Bayet, O Villeronce, L Zappia, EL Lagerqvist, S Lunke, ... Gut 66 (10), 1802-1810, 2017 | 192 | 2017 |
| Feasibility of ultra-rapid exome sequencing in critically ill infants and children with suspected monogenic conditions in the Australian public health care system S Lunke, S Eggers, M Wilson, C Patel, CP Barnett, J Pinner, ... Jama 323 (24), 2503-2511, 2020 | 150 | 2020 |
| Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone … J Hauke, M Riessland, S Lunke, IY Eyüpoglu, I Blümcke, A El-Osta, ... Human molecular genetics 18 (2), 304-317, 2009 | 150 | 2009 |
| Does genomic sequencing early in the diagnostic trajectory make a difference? A follow-up study of clinical outcomes and cost-effectiveness Z Stark, D Schofield, M Martyn, L Rynehart, R Shrestha, K Alam, S Lunke, ... Genetics in Medicine 21 (1), 173-180, 2019 | 140 | 2019 |
| Meeting the challenges of implementing rapid genomic testing in acute pediatric care Z Stark, S Lunke, GR Brett, NB Tan, R Stapleton, S Kumble, A Yeung, ... Genetics in Medicine 20 (12), 1554-1563, 2018 | 135 | 2018 |
| ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism R Desai, AE Frazier, R Durigon, H Patel, AW Jones, I Dalla Rosa, NJ Lake, ... Brain 140 (6), 1595-1610, 2017 | 129 | 2017 |
| Exome sequencing has higher diagnostic yield compared to simulated disease-specific panels in children with suspected monogenic disorders OJ Dillon, S Lunke, Z Stark, A Yeung, N Thorne, ... European Journal of Human Genetics 26 (5), 644-651, 2018 | 125 | 2018 |
| Contraction-induced interleukin-6 gene transcription in skeletal muscle is regulated by c-Jun terminal kinase/activator protein-1 M Whitham, MHS Chan, M Pal, VB Matthews, O Prelovsek, S Lunke, ... Journal of Biological Chemistry 287 (14), 10771-10779, 2012 | 121 | 2012 |
| Real-world utility of whole exome sequencing with targeted gene analysis for focal epilepsy P Perucca, IE Scheffer, AS Harvey, PA James, S Lunke, N Thorne, C Gaff, ... Epilepsy research 131, 1-8, 2017 | 105 | 2017 |
| Cpipe: a shared variant detection pipeline designed for diagnostic settings SP Sadedin, H Dashnow, PA James, M Bahlo, DC Bauer, A Lonie, ... Genome medicine 7, 1-10, 2015 | 96 | 2015 |
| Vascular histone deacetylation by pharmacological HDAC inhibition H Rafehi, A Balcerczyk, S Lunke, A Kaspi, M Ziemann, KN Harikrishnan, ... Genome research 24 (8), 1271-1284, 2014 | 89 | 2014 |
| Clinical impact of genomic testing in patients with suspected monogenic kidney disease K Jayasinghe, Z Stark, PG Kerr, C Gaff, M Martyn, J Whitlam, B Creighton, ... Genetics in medicine 23 (1), 183-191, 2021 | 80 | 2021 |
| Evaluating systematic reanalysis of clinical genomic data in rare disease from single center experience and literature review NB Tan, R Stapleton, Z Stark, MB Delatycki, A Yeung, MF Hunter, ... Molecular genetics & genomic medicine 8 (11), e1508, 2020 | 59 | 2020 |
| Response to cetuximab with or without irinotecan in patients with refractory metastatic colorectal cancer harboring the KRAS G13D mutation: Australasian Gastro-Intestinal … E Segelov, S Thavaneswaran, PM Waring, J Desai, KP Robledo, ... Journal of Clinical Oncology 34 (19), 2258-2264, 2016 | 55 | 2016 |
| Role of histone acetylation in the stimulatory effect of valproic acid on vascular endothelial tissue-type plasminogen activator expression P Larsson, E Ulfhammer, M Magnusson, N Bergh, S Lunke, A El-Osta, ... PloS one 7 (2), e31573, 2012 | 55 | 2012 |
| Exome sequencing in infants with congenital hearing impairment: a population-based cohort study L Downie, J Halliday, R Burt, S Lunke, E Lynch, M Martyn, Z Poulakis, ... European Journal of Human Genetics 28 (5), 587-596, 2020 | 50 | 2020 |
| Standardized practices for RNA diagnostics using clinically accessible specimens reclassifies 75% of putative splicing variants AM Bournazos, LG Riley, S Bommireddipalli, L Ades, LS Akesson, ... Genetics in medicine 24 (1), 130-145, 2022 | 49 | 2022 |
| Scaling national and international improvement in virtual gene panel curation via a collaborative approach to discordance resolution Z Stark, RE Foulger, E Williams, BA Thompson, C Patel, S Lunke, C Snow, ... The American Journal of Human Genetics 108 (9), 1551-1557, 2021 | 47 | 2021 |
