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Alex Berndt
Alex Berndt
Research Scientist MRC-LMB
Verified email at mrc-lmb.cam.ac.uk
Title
Cited by
Cited by
Year
The p110δ structure: mechanisms for selectivity and potency of new PI (3) K inhibitors
A Berndt, S Miller, O Williams, DD Le, BT Houseman, JI Pacold, F Gorrec, ...
Nature chemical biology 6 (2), 117-124, 2010
3362010
Structural basis for activation and inhibition of class I phosphoinositide 3-kinases
O Vadas, JE Burke, X Zhang, A Berndt, RL Williams
Science signaling 4 (195), re2-re2, 2011
3062011
A novel photoreaction mechanism for the circadian blue light photoreceptor Drosophila cryptochrome
A Berndt, T Kottke, H Breitkreuz, R Dvorsky, S Hennig, M Alexander, ...
Journal of biological chemistry 282 (17), 13011-13021, 2007
2362007
Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function
A Czarna, A Berndt, HR Singh, A Grudziecki, AG Ladurner, G Timinszky, ...
Cell 153 (6), 1394-1405, 2013
2122013
Human and Drosophila Cryptochromes Are Light Activated by Flavin Photoreduction in Living Cells
N Hoang, E Schleicher, S Kacprzak, JP Bouly, M Picot, W Wu, A Berndt, ...
PLoS biology 6 (7), e160, 2008
2052008
Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD
Ö Yildiz, M Doi, I Yujnovsky, L Cardone, A Berndt, S Hennig, S Schulze, ...
Molecular cell 17 (1), 69-82, 2005
1322005
Regulation of lipid binding underlies the activation mechanism of class IA PI3-kinases
WC Hon, A Berndt, RL Williams
Oncogene 31 (32), 3655-3666, 2012
1202012
Dynamics of the phosphoinositide 3-kinase p110δ interaction with p85α and membranes reveals aspects of regulation distinct from p110α
JE Burke, O Vadas, A Berndt, T Finegan, O Perisic, RL Williams
Structure 19 (8), 1127-1137, 2011
1172011
Architecture of human Rag GTPase heterodimers and their complex with mTORC1
M Anandapadamanaban, GR Masson, O Perisic, A Berndt, J Kaufman, ...
Science 366 (6462), 203-210, 2019
1012019
Form and flexibility in phosphoinositide 3-kinases
R Williams, A Berndt, S Miller, WC Hon, X Zhang
Biochemical Society Transactions 37 (4), 615-626, 2009
992009
Tor forms a dimer through an N-terminal helical solenoid with a complex topology
D Baretić, A Berndt, Y Ohashi, CM Johnson, RL Williams
Nature communications 7 (1), 11016, 2016
962016
Measurement of Gamma Knife® helmet factors using MOSFETs
L Kurjewicz, A Berndt
Medical physics 34 (3), 1007-1012, 2007
232007
Identification of a potent phosphoinositide 3‐kinase pan inhibitor displaying a strategic carboxylic acid group and development of its prodrugs
T Pirali, E Ciraolo, S Aprile, A Massarotti, A Berndt, A Griglio, M Serafini, ...
ChemMedChem 12 (18), 1542-1554, 2017
222017
Field-dependent ac susceptibility of amorphous (: Weakly frustrated regime
AG Berndt, X Chen, HP Kunkel, G Williams
Physical Review B 52 (14), 10160, 1995
181995
An algorithm for independent verification of Gamma Knife™ treatment plans
J Beck, A Berndt
Medical physics 31 (10), 2780-2784, 2004
142004
Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace
M Heimhalt, A Berndt, J Wagstaff, M Anandapadamanaban, O Perisic, ...
Elife 10, e68799, 2021
102021
COMP report: CPQR technical quality control guidelines for Gamma Knife radiosurgery
A Berndt, M van Prooijen, M Guillot
Journal of Applied Clinical Medical Physics 19 (5), 365-367, 2018
72018
Effect of skull shape approximations in Gamma Knife dose calculations
A Berndt, J Beck
Journal of Applied Clinical Medical Physics 8 (3), 52-59, 2007
72007
Field-dependent ac susceptibility of amorphous: the strongly frustrated regime
AG Berndt, HP Kunkel, G Williams
Journal of Physics: Condensed Matter 10 (38), 8535, 1998
71998
Size and positioning reproducibility of an brachytherapy stepping source
A Berndt, DW Rickey, S Rathee, J Bews
Medical Physics 27 (1), 129-131, 2000
52000
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