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Thomas Kelley
Thomas Kelley
Verified email at case.edu
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Year
Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells.
TJ Kelley, ML Drumm
The Journal of clinical investigation 102 (6), 1200-1207, 1998
3311998
CFTR inhibition mimics the cystic fibrosis inflammatory profile
A Perez, AC Issler, CU Cotton, TJ Kelley, AS Verkman, PB Davis
American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (2 …, 2007
2422007
Dysfunction of Nrf-2 in CF Epithelia Leads to Excess Intracellular H2O2 and Inflammatory Cytokine Production
J Chen, M Kinter, S Shank, C Cotton, TJ Kelley, AG Ziady
PloS one 3 (10), e3367, 2008
1472008
Altered cholesterol homeostasis in cultured and in vivo models of cystic fibrosis
NM White, D Jiang, JD Burgess, IR Bederman, SF Previs, TJ Kelley
American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (2 …, 2007
1182007
In vivo activation of the cystic fibrosis transmembrane conductance regulator mutant ΔF508 in murine nasal epithelium
TJ Kelley, K Thomas, LJH Milgram, ML Drumm
Proceedings of the National Academy of Sciences 94 (6), 2604-2608, 1997
1011997
CFTR-mediated chloride permeability is regulated by type III phosphodiesterases in airway epithelial cells.
TJ Kelley, L Al-Nakkash, ML Drumm
American journal of respiratory cell and molecular biology 13 (6), 657-664, 1995
1001995
Cystic fibrosis transmembrane conductance regulator–dependent regulation of epithelial inducible nitric oxide synthase expression
WK Steagall, HL Elmer, KG Brady, TJ Kelley
American Journal of Respiratory Cell and Molecular Biology 22 (1), 45-50, 2000
992000
Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells
NE Kreiselmeier, NC Kraynack, DA Corey, TJ Kelley
American Journal of Physiology-Lung Cellular and Molecular Physiology 285 (6 …, 2003
872003
Functional evidence of CFTR gene transfer in nasal epithelium of cystic fibrosis mice in vivo following luminal application of DNA complexes targeted to the serpin-enzyme …
AG Ziady, TJ Kelley, E Milliken, T Ferkol, PB Davis
Molecular Therapy 5 (4), 413-419, 2002
862002
Cyclin-dependent kinase and initiation at eukaryotic origins: a replication switch?
PV Jallepalli, TJ Kelley
Current opinion in cell biology 9 (3), 358-363, 1997
731997
Interaction with CREB binding protein modulates the activities of Nrf2 and NF-κB in cystic fibrosis airway epithelial cells
AG Ziady, A Sokolow, S Shank, D Corey, R Myers, S Plafker, TJ Kelley
American Journal of Physiology-Lung Cellular and Molecular Physiology 302 …, 2012
712012
Use of nasal potential difference and sweat chloride as outcome measures in multicenter clinical trials in subjects with cystic fibrosis
RC Ahrens, TA Standaert, J Launspach, SH Han, ME Teresi, ML Aitken, ...
Pediatric pulmonology 33 (2), 142-150, 2002
702002
In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium
TJ Kelley, HL Elmer
The Journal of clinical investigation 106 (3), 403-410, 2000
702000
Mechanisms of NOS2 regulation by Rho GTPase signaling in airway epithelial cells
NC Kraynack, DA Corey, HL Elmer, TJ Kelley
American Journal of Physiology-Lung Cellular and Molecular Physiology 283 (3 …, 2002
682002
Biomarkers for cystic fibrosis drug development
MS Muhlebach, JP Clancy, SL Heltshe, A Ziady, T Kelley, F Accurso, ...
Journal of Cystic Fibrosis 15 (6), 714-723, 2016
662016
A phase I randomized, multicenter trial of CPX in adult subjects with mild cystic fibrosis
NA McCarty, TA Standaert, M Teresi, C Tuthill, J Launspach, TJ Kelley, ...
Pediatric pulmonology 33 (2), 90-98, 2002
652002
Reduced Smad3 Protein Expression and Altered Transforming Growth Factor-β 1–Mediated Signaling in Cystic Fibrosis Epithelial Cells
TJ Kelley, HL Elmer, DA Corey
American journal of respiratory cell and molecular biology 25 (6), 732-738, 2001
652001
Nitric oxide deficiency contributes to impairment of airway relaxation in cystic fibrosis mice
MJ Mhanna, T Ferkol, RJ Martin, IA Dreshaj, AM Van Heeckeren, ...
American journal of respiratory cell and molecular biology 24 (5), 621-626, 2001
602001
Differential topical susceptibility to TGFβ in intact and injured regions of the epithelium: key role in myofibroblast transition
P Speight, H Nakano, TJ Kelley, B Hinz, A Kapus
Molecular biology of the cell 24 (21), 3326-3336, 2013
592013
Activation of endogenous deltaF508 cystic fibrosis transmembrane conductance regulator by phosphodiesterase inhibition.
TJ Kelley, L Al-Nakkash, CU Cotton, ML Drumm
The Journal of clinical investigation 98 (2), 513-520, 1996
581996
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