Inducible nitric oxide synthase expression is reduced in cystic fibrosis murine and human airway epithelial cells. TJ Kelley, ML Drumm The Journal of clinical investigation 102 (6), 1200-1207, 1998 | 331 | 1998 |
CFTR inhibition mimics the cystic fibrosis inflammatory profile A Perez, AC Issler, CU Cotton, TJ Kelley, AS Verkman, PB Davis American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (2 …, 2007 | 242 | 2007 |
Dysfunction of Nrf-2 in CF Epithelia Leads to Excess Intracellular H2O2 and Inflammatory Cytokine Production J Chen, M Kinter, S Shank, C Cotton, TJ Kelley, AG Ziady PloS one 3 (10), e3367, 2008 | 147 | 2008 |
Altered cholesterol homeostasis in cultured and in vivo models of cystic fibrosis NM White, D Jiang, JD Burgess, IR Bederman, SF Previs, TJ Kelley American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (2 …, 2007 | 118 | 2007 |
In vivo activation of the cystic fibrosis transmembrane conductance regulator mutant ΔF508 in murine nasal epithelium TJ Kelley, K Thomas, LJH Milgram, ML Drumm Proceedings of the National Academy of Sciences 94 (6), 2604-2608, 1997 | 101 | 1997 |
CFTR-mediated chloride permeability is regulated by type III phosphodiesterases in airway epithelial cells. TJ Kelley, L Al-Nakkash, ML Drumm American journal of respiratory cell and molecular biology 13 (6), 657-664, 1995 | 100 | 1995 |
Cystic fibrosis transmembrane conductance regulator–dependent regulation of epithelial inducible nitric oxide synthase expression WK Steagall, HL Elmer, KG Brady, TJ Kelley American Journal of Respiratory Cell and Molecular Biology 22 (1), 45-50, 2000 | 99 | 2000 |
Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells NE Kreiselmeier, NC Kraynack, DA Corey, TJ Kelley American Journal of Physiology-Lung Cellular and Molecular Physiology 285 (6 …, 2003 | 87 | 2003 |
Functional evidence of CFTR gene transfer in nasal epithelium of cystic fibrosis mice in vivo following luminal application of DNA complexes targeted to the serpin-enzyme … AG Ziady, TJ Kelley, E Milliken, T Ferkol, PB Davis Molecular Therapy 5 (4), 413-419, 2002 | 86 | 2002 |
Cyclin-dependent kinase and initiation at eukaryotic origins: a replication switch? PV Jallepalli, TJ Kelley Current opinion in cell biology 9 (3), 358-363, 1997 | 73 | 1997 |
Interaction with CREB binding protein modulates the activities of Nrf2 and NF-κB in cystic fibrosis airway epithelial cells AG Ziady, A Sokolow, S Shank, D Corey, R Myers, S Plafker, TJ Kelley American Journal of Physiology-Lung Cellular and Molecular Physiology 302 …, 2012 | 71 | 2012 |
Use of nasal potential difference and sweat chloride as outcome measures in multicenter clinical trials in subjects with cystic fibrosis RC Ahrens, TA Standaert, J Launspach, SH Han, ME Teresi, ML Aitken, ... Pediatric pulmonology 33 (2), 142-150, 2002 | 70 | 2002 |
In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium TJ Kelley, HL Elmer The Journal of clinical investigation 106 (3), 403-410, 2000 | 70 | 2000 |
Mechanisms of NOS2 regulation by Rho GTPase signaling in airway epithelial cells NC Kraynack, DA Corey, HL Elmer, TJ Kelley American Journal of Physiology-Lung Cellular and Molecular Physiology 283 (3 …, 2002 | 68 | 2002 |
Biomarkers for cystic fibrosis drug development MS Muhlebach, JP Clancy, SL Heltshe, A Ziady, T Kelley, F Accurso, ... Journal of Cystic Fibrosis 15 (6), 714-723, 2016 | 66 | 2016 |
A phase I randomized, multicenter trial of CPX in adult subjects with mild cystic fibrosis NA McCarty, TA Standaert, M Teresi, C Tuthill, J Launspach, TJ Kelley, ... Pediatric pulmonology 33 (2), 90-98, 2002 | 65 | 2002 |
Reduced Smad3 Protein Expression and Altered Transforming Growth Factor-β 1–Mediated Signaling in Cystic Fibrosis Epithelial Cells TJ Kelley, HL Elmer, DA Corey American journal of respiratory cell and molecular biology 25 (6), 732-738, 2001 | 65 | 2001 |
Nitric oxide deficiency contributes to impairment of airway relaxation in cystic fibrosis mice MJ Mhanna, T Ferkol, RJ Martin, IA Dreshaj, AM Van Heeckeren, ... American journal of respiratory cell and molecular biology 24 (5), 621-626, 2001 | 60 | 2001 |
Differential topical susceptibility to TGFβ in intact and injured regions of the epithelium: key role in myofibroblast transition P Speight, H Nakano, TJ Kelley, B Hinz, A Kapus Molecular biology of the cell 24 (21), 3326-3336, 2013 | 59 | 2013 |
Activation of endogenous deltaF508 cystic fibrosis transmembrane conductance regulator by phosphodiesterase inhibition. TJ Kelley, L Al-Nakkash, CU Cotton, ML Drumm The Journal of clinical investigation 98 (2), 513-520, 1996 | 58 | 1996 |