|Somatic mutation, genomic variation, and neurological disease|
A Poduri, GD Evrony, X Cai, CA Walsh
Science 341 (6141), 2013
|Single-neuron sequencing analysis of L1 retrotransposition and somatic mutation in the human brain|
GD Evrony, X Cai, E Lee, LB Hills, PC Elhosary, HS Lehmann, JJ Parker, ...
Cell 151 (3), 483-496, 2012
|Somatic mutation in single human neurons tracks developmental and transcriptional history|
MA Lodato, MB Woodworth, S Lee, GD Evrony, BK Mehta, A Karger, ...
Science 350 (6256), 94-98, 2015
|Somatic activation of AKT3 causes hemispheric developmental brain malformations|
A Poduri, GD Evrony, X Cai, PC Elhosary, R Beroukhim, MK Lehtinen, ...
Neuron 74 (1), 41-48, 2012
|Single-cell, genome-wide sequencing identifies clonal somatic copy-number variation in the human brain|
X Cai, GD Evrony, HS Lehmann, PC Elhosary, BK Mehta, A Poduri, ...
Cell reports 8 (5), 1280-1289, 2014
|Human mutations in NDE1 cause extreme microcephaly with lissencephaly|
FS Alkuraya, X Cai, C Emery, GH Mochida, MS Al-Dosari, JM Felie, ...
The American Journal of Human Genetics 88 (5), 536-547, 2011
|Cell lineage analysis in human brain using endogenous retroelements|
GD Evrony, E Lee, BK Mehta, Y Benjamini, RM Johnson, X Cai, L Yang, ...
Neuron 85 (1), 49-59, 2015
|Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells|
L Yang, D Grishin, G Wang, J Aach, CZ Zhang, R Chari, J Homsy, X Cai, ...
Nature communications 5 (1), 1-6, 2014
|A proximal centriole-like structure is present in Drosophila spermatids and can serve as a model to study centriole duplication|
S Blachon, X Cai, KA Roberts, K Yang, A Polyanovsky, A Church, ...
Genetics 182 (1), 133-144, 2009
|Accessing genetic information with liquid biopsies|
X Cai, F Janku, Q Zhan, JB Fan
Trends in Genetics 31 (10), 564-575, 2015
|Non-invasive diagnosis of early-stage lung cancer using high-throughput targeted DNA methylation sequencing of circulating tumor DNA (ctDNA)|
W Liang, Y Zhao, W Huang, Y Gao, W Xu, J Tao, M Yang, L Li, W Ping, ...
Theranostics 9 (7), 2056, 2019
|Development and validation of an ultradeep next-generation sequencing assay for testing of plasma cell-free DNA from patients with advanced cancer|
F Janku, S Zhang, J Waters, L Liu, HJ Huang, V Subbiah, DS Hong, ...
Clinical Cancer Research 23 (18), 5648-5656, 2017
|Enrichment of short mutant cell-free DNA fragments enhanced detection of pancreatic cancer|
X Liu, L Liu, Y Ji, C Li, T Wei, X Yang, Y Zhang, X Cai, Y Gao, W Xu, ...
EBioMedicine 41, 345-356, 2019
|Non-invasive diagnosis of early-stage lung cancer via targeted high-throughput DNA methylation sequencing of circulating tumor DNA (ctDNA)|
X Cai, Y Gao, H Shen, P Laird, J Fan, W Xu, W Liang, J He
Cancer Research 77 (13 Supplement), 5383-5383, 2017
|Non-invasive diagnosis of colorectal cancer via targeted high-throughput DNA methylation sequencing of circulating tumor DNA (ctDNA)|
X Wu, J Chuan, T Hu, T Peng, M Yang, H Shen, P Laird, Y Gao, X Cai, ...
Cancer Research 78 (13 Supplement), 3310-3310, 2018
|P3. 02-008 Non-Invasive Diagnosis of Solitary Pulmonary Nodules Using High-Throughput Targeted DNA Methylation Sequencing of Circulating Tumor DNA|
W Liang, Y Zhao, W Huang, Y Gao, W Wang, W Xu, L Li, H Shen, X Fu, ...
Journal of Thoracic Oncology 12 (11), S2240, 2017
|Ultra-deep next-generation sequencing of plasma cell-free (cf) DNA from patients with advanced cancers.|
F Janku, HJ Huang, NM Ramzanali, DS Hong, DD Karp, S Fu, X Cai, ...
Journal of Clinical Oncology 33 (15_suppl), e22168-e22168, 2015
|Flow tracing based on current.|
X Cai, H Cao
Journal of Harbin Institute of Technology(New Series) 8 (4), 317-319, 2001
|A novel cell‐free DNA methylation‐based model improves the early detection of colorectal cancer|
X Wu, Y Zhang, T Hu, X He, Y Zou, Q Deng, J Ke, L Lian, X He, D Zhao, ...
Molecular Oncology, 2021
|Method for Detecting Methylated DNA|
JB Fan, X Cai, GAO Yangbin
US Patent App. 15/424,748, 2017