Alper Okyar
Alper Okyar
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Cited by
Circadian timing in cancer treatments
F Lévi, A Okyar, S Dulong, PF Innominato, J Clairambault
Annual review of pharmacology and toxicology 50, 377-421, 2010
Effect of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models
A Okyar, A Can, N Akev, G Baktir, N Sütlüpinar
Phytotherapy Research 15 (2), 157-161, 2001
Dosing-time makes the poison: circadian regulation and pharmacotherapy
R Dallmann, A Okyar, F Lévi
Trends in molecular medicine 22 (5), 430-445, 2016
Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models
A Can, N Akev, N Ozsoy, S Bolkent, BP Arda, R Yanardag, A Okyar
Biological and Pharmaceutical Bulletin 27 (5), 694-698, 2004
P-glycoprotein transporters and the gastrointestinal tract: evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound.
H Spahn-Langguth, G Baktir, A Radschuweit, A Okyar, B Terhaag, P Ader, ...
International journal of clinical pharmacology and therapeutics 36 (1), 16-24, 1998
Circadian clocks and drug delivery systems: impact and opportunities in chronotherapeutics
F Lévi, A Okyar
Expert opinion on drug delivery 8 (12), 1535-1541, 2011
Effect of Aloe vera (L.) Burm. fil. leaf gel and pulp extracts on kidney in type-II diabetic rat models
S Bolkent, N Akev, N Ozsoy, M Sengezer-Inceli, A Can, A Okyar, ...
NISCAIR-CSIR, India, 2004
Molecular aspects of circadian pharmacology and relevance for cancer chronotherapy
N Ozturk, D Ozturk, I Halil Kavakli, A Okyar
International journal of molecular sciences 18 (10), 2168, 2017
A combined experimental and mathematical approach for molecular-based optimization of irinotecan circadian delivery
A Ballesta, S Dulong, C Abbara, B Cohen, A Okyar, J Clairambault, F Levi
PLoS computational biology 7 (9), e1002143, 2011
Identification of Circadian Determinants of Cancer Chronotherapy through In Vitro Chronopharmacology and Mathematical Modeling
S Dulong, A Ballesta, A Okyar, F Lévi
Molecular cancer therapeutics 14 (9), 2154-2164, 2015
Clock gene Per2 as a controller of liver carcinogenesis
A Mteyrek, E Filipski, C Guettier, A Okyar, F Lévi
Oncotarget 7 (52), 85832, 2016
In Vitro and Ex Vivo Permeation Studies of Etodolac from Hydrophilic Gels and Effect of Terpenes as Enhancers
C Tas, Y Ozkan, A Okyar, A Savaser
Drug delivery 14 (7), 453-459, 2007
In silico identification of widely used and well-tolerated drugs as potential SARS-CoV-2 3C-like protease and viral RNA-dependent RNA polymerase inhibitors for direct use in …
S Gul, O Ozcan, S Asar, A Okyar, I Barýs, IH Kavakli
Journal of Biomolecular Structure and Dynamics 39 (17), 6772-6791, 2021
A CLOCK-binding small molecule disrupts the interaction between CLOCK and BMAL1 and enhances circadian rhythm amplitude
YU Doruk, D Yarparvar, YK Akyel, S Gul, AC Taskin, F Yilmaz, I Baris, ...
Journal of Biological Chemistry 295 (11), 3518-3531, 2020
Circadian variations in exsorptive transport: in situ intestinal perfusion data and in vivo relevance
A Okyar, C Dressler, A Hanafy, G Baktir, B Lemmer, H Spahn-Langguth
Chronobiology international 29 (4), 443-453, 2012
Strain-and sex-dependent circadian changes in abcc2 transporter expression: implications for irinotecan chronotolerance in mouse ileum
A Okyar, E Piccolo, C Ahowesso, E Filipski, V Hossard, C Guettier, ...
PloS one 6 (6), e20393, 2011
Reproductive effects of subchronic exposure to acetamiprid in male rats
EY Arýcan, D Gökçeođlu Kayalý, B Ulus Karaca, T Boran, N Öztürk, ...
Scientific reports 10 (1), 8985, 2020
Optimization of irinotecan chronotherapy with P-glycoprotein inhibition
E Filipski, E Berland, N Ozturk, C Guettier, GTJ van der Horst, F Lévi, ...
Toxicology and applied pharmacology 274 (3), 471-479, 2014
Ondansetron-loaded chitosan microspheres for nasal antiemetic drug delivery: an alternative approach to oral and parenteral routes
S Gungor, A Okyar, S Erturk-Toker, G Baktir, Y Ozsoy
Drug development and industrial pharmacy 36 (7), 806-813, 2010
Critical cholangiocarcinogenesis control by cryptochrome clock genes
A Mteyrek, E Filipski, C Guettier, M Oklejewicz, GTJ van der Horst, ...
International journal of cancer 140 (11), 2473-2483, 2017
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