Circadian timing in cancer treatments F Lévi, A Okyar, S Dulong, PF Innominato, J Clairambault Annual review of pharmacology and toxicology 50 (1), 377-421, 2010 | 523 | 2010 |
Effect of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models A Okyar, A Can, N Akev, G Baktir, N Sütlüpinar Phytotherapy Research 15 (2), 157-161, 2001 | 362 | 2001 |
Dosing-time makes the poison: circadian regulation and pharmacotherapy R Dallmann, A Okyar, F Lévi Trends in molecular medicine 22 (5), 430-445, 2016 | 265 | 2016 |
Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models A Can, N Akev, N Ozsoy, S Bolkent, BP Arda, R Yanardag, A Okyar Biological and Pharmaceutical Bulletin 27 (5), 694-698, 2004 | 227 | 2004 |
P-glycoprotein transporters and the gastrointestinal tract: evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound. H Spahn-Langguth, G Baktir, A Radschuweit, A Okyar, B Terhaag, P Ader, ... International journal of clinical pharmacology and therapeutics 36 (1), 16-24, 1998 | 151 | 1998 |
Molecular aspects of circadian pharmacology and relevance for cancer chronotherapy N Ozturk, D Ozturk, I Halil Kavakli, A Okyar International journal of molecular sciences 18 (10), 2168, 2017 | 100 | 2017 |
Circadian clocks and drug delivery systems: impact and opportunities in chronotherapeutics F Lévi, A Okyar Expert opinion on drug delivery 8 (12), 1535-1541, 2011 | 95 | 2011 |
Effect of Aloe vera (L.) Burm. fil. leaf gel and pulp extracts on kidney in type-II diabetic rat models S Bolkent, N Akev, N Ozsoy, M Sengezer-Inceli, A Can, A Okyar, ... NISCAIR-CSIR, India, 2004 | 91 | 2004 |
A combined experimental and mathematical approach for molecular-based optimization of irinotecan circadian delivery A Ballesta, S Dulong, C Abbara, B Cohen, A Okyar, J Clairambault, F Levi PLoS computational biology 7 (9), e1002143, 2011 | 84 | 2011 |
Identification of Circadian Determinants of Cancer Chronotherapy through In Vitro Chronopharmacology and Mathematical Modeling S Dulong, A Ballesta, A Okyar, F Lévi Molecular cancer therapeutics 14 (9), 2154-2164, 2015 | 79 | 2015 |
In Vitro and Ex Vivo Permeation Studies of Etodolac from Hydrophilic Gels and Effect of Terpenes as Enhancers C Tas, Y Ozkan, A Okyar, A Savaser Drug delivery 14 (7), 453-459, 2007 | 74 | 2007 |
Clock gene Per2 as a controller of liver carcinogenesis A Mteyrek, E Filipski, C Guettier, A Okyar, F Lévi Oncotarget 7 (52), 85832, 2016 | 72 | 2016 |
In silico identification of widely used and well-tolerated drugs as potential SARS-CoV-2 3C-like protease and viral RNA-dependent RNA polymerase inhibitors for direct use in … S Gul, O Ozcan, S Asar, A Okyar, I Barýs, IH Kavakli Journal of Biomolecular Structure and Dynamics 39 (17), 6772-6791, 2021 | 63 | 2021 |
A CLOCK-binding small molecule disrupts the interaction between CLOCK and BMAL1 and enhances circadian rhythm amplitude YU Doruk, D Yarparvar, YK Akyel, S Gul, AC Taskin, F Yilmaz, I Baris, ... Journal of Biological Chemistry 295 (11), 3518-3531, 2020 | 62 | 2020 |
Reproductive effects of subchronic exposure to acetamiprid in male rats EY Arýcan, D Gökçeođlu Kayalý, B Ulus Karaca, T Boran, N Öztürk, ... Scientific reports 10 (1), 8985, 2020 | 57 | 2020 |
Circadian variations in exsorptive transport: in situ intestinal perfusion data and in vivo relevance A Okyar, C Dressler, A Hanafy, G Baktir, B Lemmer, H Spahn-Langguth Chronobiology international 29 (4), 443-453, 2012 | 53 | 2012 |
Strain-and sex-dependent circadian changes in abcc2 transporter expression: implications for irinotecan chronotolerance in mouse ileum A Okyar, E Piccolo, C Ahowesso, E Filipski, V Hossard, C Guettier, ... PloS one 6 (6), e20393, 2011 | 51 | 2011 |
Optimization of irinotecan chronotherapy with P-glycoprotein inhibition E Filipski, E Berland, N Ozturk, C Guettier, GTJ van der Horst, F Lévi, ... Toxicology and applied pharmacology 274 (3), 471-479, 2014 | 47 | 2014 |
Ondansetron-loaded chitosan microspheres for nasal antiemetic drug delivery: an alternative approach to oral and parenteral routes S Gungor, A Okyar, S Erturk-Toker, G Baktir, Y Ozsoy Drug development and industrial pharmacy 36 (7), 806-813, 2010 | 45 | 2010 |
Critical cholangiocarcinogenesis control by cryptochrome clock genes A Mteyrek, E Filipski, C Guettier, M Oklejewicz, GTJ van der Horst, ... International journal of cancer 140 (11), 2473-2483, 2017 | 42 | 2017 |