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Jan Krönke
Jan Krönke
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Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells
J Krönke, ND Udeshi, A Narla, P Grauman, SN Hurst, M McConkey, ...
Science 343 (6168), 301-305, 2014
16402014
IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 …
P Paschka, RF Schlenk, VI Gaidzik, M Habdank, J Kronke, L Bullinger, ...
J Clin Oncol 28 (22), 3636-3643, 2010
9972010
Lenalidomide induces ubiquitination and degradation of CK1α in del (5q) MDS
J Krönke, EC Fink, PW Hollenbach, KJ MacBeth, SN Hurst, ND Udeshi, ...
Nature 523 (7559), 183-188, 2015
7982015
Monitoring of Minimal Residual Disease in NPM1-Mutated Acute Myeloid Leukemia: A Study From the German-Austrian Acute Myeloid Leukemia Study Group
J Krönke, RF Schlenk, KO Jensen, F Tschürtz, A Corbacioglu, VI Gaidzik, ...
Journal of Clinical Oncology 29 (19), 2709-2716, 2011
4812011
Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia
J Krönke, L Bullinger, V Teleanu, F Tschürtz, VI Gaidzik, MWM Kühn, ...
Blood, The Journal of the American Society of Hematology 122 (1), 100-108, 2013
3132013
Anti–B-cell maturation antigen BiTE molecule AMG 420 induces responses in multiple myeloma
MS Topp, J Duell, G Zugmaier, M Attal, P Moreau, C Langer, J Krönke, ...
Journal of Clinical Oncology 38 (8), 775-783, 2020
2712020
Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs
J Kronke, R Kittler, F Buchholz, MP Windisch, T Pietschmann, ...
Journal of virology 78 (7), 3436-3446, 2004
2432004
Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing
A Dolnik, JC Engelmann, M Scharfenberger-Schmeer, J Mauch, ...
Blood, The Journal of the American Society of Hematology 120 (18), e83-e92, 2012
1772012
Identification of acquired copy number alterations and uniparental disomies in cytogenetically normal acute myeloid leukemia using high-resolution single-nucleotide …
L Bullinger, J Krönke, C Schön, I Radtke, K Urlbauer, U Botzenhardt, ...
Leukemia 24 (2), 438-449, 2010
1572010
Homo-PROTACs for the chemical knockdown of cereblon
C Steinebach, S Lindner, ND Udeshi, DC Mani, H Kehm, S Köpff, ...
ACS chemical biology 13 (9), 2771-2782, 2018
1342018
Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation
S Cocciardi, A Dolnik, S Kapp-Schwoerer, FG Rücker, S Lux, TJ Blätte, ...
Nature Communications 10 (1), 2031, 2019
1102019
High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations
MWM Kühn, I Radtke, L Bullinger, S Goorha, J Cheng, J Edelmann, ...
Blood, The Journal of the American Society of Hematology 119 (10), e67-e75, 2012
932012
PROTAC-mediated crosstalk between E3 ligases
C Steinebach, H Kehm, S Lindner, LP Vu, S Köpff, ÁL Mármol, C Weiler, ...
Chemical communications 55 (12), 1821-1824, 2019
922019
Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders
C Steinebach, YLD Ng, I Sosič, CS Lee, S Chen, S Lindner, LP Vu, ...
Chemical science 11 (13), 3474-3486, 2020
902020
Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1-mutated AML: results from the AMLSG 09-09 trial
S Kapp-Schwoerer, D Weber, A Corbacioglu, VI Gaidzik, P Paschka, ...
Blood, The Journal of the American Society of Hematology 136 (26), 3041-3050, 2020
852020
Lenalidomide induces degradation of IKZF1 and IKZF3
J Krönke, SN Hurst, BL Ebert
Oncoimmunology 3 (7), e941742, 2014
762014
Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia
S Hirsch, TJ Blätte, S Grasedieck, S Cocciardi, A Rouhi, ...
haematologica 102 (12), 2039, 2017
752017
DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acute myeloid leukemia
VI Gaidzik, D Weber, P Paschka, A Kaumanns, S Krieger, A Corbacioglu, ...
Leukemia 32 (1), 30-37, 2018
652018
Comparison between 5-azacytidine treatment and allogeneic stem-cell transplantation in elderly patients with advanced MDS according to donor availability (VidazaAllo Study)
N Kröger, K Sockel, C Wolschke, W Bethge, RF Schlenk, D Wolf, ...
Journal of Clinical Oncology 39 (30), 3318-3327, 2021
582021
The molecular mechanism of thalidomide analogs in hematologic malignancies
S Lindner, J Krönke
Journal of molecular medicine 94 (12), 1327-1334, 2016
562016
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