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Daniel J. Weston
Daniel J. Weston
Verified email at gsk.com
Title
Cited by
Cited by
Year
Ambient ionization mass spectrometry: current understanding of mechanistic theory; analytical performance and application areas
DJ Weston
Analyst 135 (4), 661-668, 2010
4402010
Direct analysis of pharmaceutical drug formulations using ion mobility spectrometry/quadrupole-time-of-flight mass spectrometry combined with desorption electrospray ionization
DJ Weston, R Bateman, ID Wilson, TR Wood, CS Creaser
Analytical chemistry 77 (23), 7572-7580, 2005
2772005
Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo [3.1. 0] hexyl …
MD McBriar, H Guzik, S Shapiro, J Paruchova, R Xu, A Palani, JW Clader, ...
Journal of medicinal chemistry 49 (7), 2294-2310, 2006
942006
Analysis of tryptic peptides using desorption electrospray ionisation combined with ion mobility spectrometry/mass spectrometry
G Kaur‐Atwal, DJ Weston, PS Green, S Crosland, PLR Bonner, ...
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2007
752007
An approach to enhancing coverage of the urinary metabonome using liquid chromatography–ion mobility–mass spectrometry
EL Harry, DJ Weston, AWT Bristow, ID Wilson, CS Creaser
Journal of chromatography B 871 (2), 357-361, 2008
652008
Utility of spatially-resolved atmospheric pressure surface sampling and ionization techniques as alternatives to mass spectrometric imaging (MSI) in drug metabolism
EQ Blatherwick, GJ Van Berkel, K Pickup, MK Johansson, ME Beaudoin, ...
Xenobiotica 41 (8), 720-734, 2011
532011
Diagnostic biomarkers differentiating metastatic melanoma patients from healthy controls identified by an integrated MALDI‐TOF mass spectrometry/bioinformatic approach
B Matharoo‐Ball, L Ratcliffe, L Lancashire, S Ugurel, AK Miles, DJ Weston, ...
PROTEOMICS–Clinical Applications 1 (6), 605-620, 2007
512007
Enhanced analyte detection using in-source fragmentation of field asymmetric waveform ion mobility spectrometry-selected ions in combination with time-of-flight mass spectrometry
LJ Brown, RW Smith, DE Toutoungi, JC Reynolds, AWT Bristow, A Ray, ...
Analytical chemistry 84 (9), 4095-4103, 2012
462012
Analysis of pharmaceutical formulations using atmospheric pressure ion mobility spectrometry combined with liquid chromatography and nano-electrospray ionisation
N Budimir, DJ Weston, CS Creaser
Analyst 132 (1), 34-40, 2007
452007
In-membrane preconcentration/membrane inlet mass spectrometry of volatile and semivolatile organic compounds
CS Creaser, DJ Weston, B Smith
Analytical chemistry 72 (13), 2730-2736, 2000
422000
Bicyclic [4.1. 0] heptanes as phenyl replacements for melanin concentrating hormone receptor antagonists
R Xu, S Li, J Paruchova, MD McBriar, H Guzik, A Palani, JW Clader, ...
Bioorganic & medicinal chemistry 14 (10), 3285-3299, 2006
352006
Direct detection of a sulfonate ester genotoxic impurity by atmospheric-pressure thermal desorption–extractive electrospray–mass spectrometry
NA Devenport, LC Sealey, FH Alruways, DJ Weston, JC Reynolds, ...
Analytical chemistry 85 (13), 6224-6227, 2013
292013
Determination of free desmosine and isodesmosine as urinary biomarkers of lung disorder using ultra performance liquid chromatography–ion mobility-mass spectrometry
NA Devenport, JC Reynolds, V Parkash, J Cook, DJ Weston, CS Creaser
Journal of chromatography B 879 (32), 3797-3801, 2011
282011
Quantification of proteins by flow cytometry: Quantification of human hepatic transporter P-gp and OATP1B1 using flow cytometry and mass spectrometry
K Hogg, J Thomas, D Ashford, J Cartwright, R Coldwell, DJ Weston, ...
Methods 82, 38-46, 2015
262015
Direct determination of urinary creatinine by reactive-thermal desorption-extractive electrospray-ion mobility-tandem mass spectrometry.
NA Devenport, DJ Blenkhorn, DJ Weston, JC Reynolds, CS Creaser
Analytical chemistry 86 (1), 357-361, 2014
262014
Enhanced performance in the determination of ibuprofen 1-β-O-acyl glucuronide in urine by combining high field asymmetric waveform ion mobility spectrometry with liquid …
RW Smith, DE Toutoungi, JC Reynolds, AWT Bristow, A Ray, A Sage, ...
Journal of chromatography A 1278, 76-81, 2013
262013
Reactive metabolite trapping screens and potential pitfalls: bioactivation of a homomorpholine and formation of an unstable thiazolidine adduct
EM Lenz, S Martin, R Schmidt, PE Morin, R Smith, DJ Weston, ...
Chemical Research in Toxicology 27 (6), 968-980, 2014
232014
Evaluation of laser diode thermal desorption (LDTD) coupled with tandem mass spectrometry (MS/MS) for support of in vitro drug discovery assays: Increasing scope, robustness …
I Beattie, A Smith, DJ Weston, P White, S Szwandt, L Sealey
Journal of pharmaceutical and biomedical analysis 59, 18-28, 2012
232012
Design and synthesis of orally efficacious benzimidazoles as melanin-concentrating hormone receptor 1 antagonists
WL Wu, DA Burnett, MA Caplen, MS Domalski, C Bennett, WJ Greenlee, ...
Bioorganic & medicinal chemistry letters 16 (14), 3674-3678, 2006
232006
Bicyclo [3.1. 0] hexyl urea melanin concentrating hormone (MCH) receptor-1 antagonists: Impacting hERG liability via aryl modifications
MD McBriar, H Guzik, S Shapiro, R Xu, J Paruchova, JW Clader, K O’Neill, ...
Bioorganic & medicinal chemistry letters 16 (16), 4262-4265, 2006
202006
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