Alexandre Amlie-Wolf
Alexandre Amlie-Wolf
Computational Biologist, Arrakis Therapeutics
Verified email at arrakistx.com - Homepage
Title
Cited by
Cited by
Year
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
5322019
Dysregulation of the epigenetic landscape of normal aging in Alzheimer’s disease
R Nativio, G Donahue, A Berson, Y Lan, A Amlie-Wolf, F Tuzer, JB Toledo, ...
Nature neuroscience 21 (4), 497-505, 2018
932018
DASHR: database of small human noncoding RNAs
YY Leung, PP Kuksa, A Amlie-Wolf, O Valladares, LH Ungar, S Kannan, ...
Nucleic acids research 44 (D1), D216-D222, 2016
622016
Transcriptomic changes due to cytoplasmic TDP-43 expression reveal dysregulation of histone transcripts and nuclear chromatin
A Amlie-Wolf, P Ryvkin, R Tong, I Dragomir, ER Suh, Y Xu, ...
PLoS One 10 (10), 2015
332015
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons
EY Liu, J Russ, CP Cali, JM Phan, A Amlie-Wolf, EB Lee
Cell reports 27 (5), 1409-1421. e6, 2019
312019
DASHR 2.0: integrated database of human small non-coding RNA genes and mature products
PP Kuksa, A Amlie-Wolf, Z Katanic, O Valladares, LS Wang, YY Leung
Bioinformatics 1, 7, 2018
292018
Alzheimer Disease Genetics Consortium (ADGC); European Alzheimer’s Disease Initiative (EADI); Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE …
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nat. Genet 51, 414-430, 0
25*
INFERNO: inferring the molecular mechanisms of noncoding genetic variants
A Amlie-Wolf, M Tang, EE Mlynarski, PP Kuksa, O Valladares, Z Katanic, ...
Nucleic Acids Research, 2018
232018
SPAR: small RNA-seq portal for analysis of sequencing experiments
PP Kuksa, A Amlie-Wolf, Ž Katanić, O Valladares, LS Wang, YY Leung
Nucleic acids research 46 (W1), W36-W42, 2018
82018
Inferring the molecular mechanisms of noncoding Alzheimer’s disease-associated genetic variants
A Amlie-Wolf, M Tang, J Way, B Dombroski, M Jiang, N Vrettos, YF Chou, ...
Journal of Alzheimer's Disease 72 (1), 301-318, 2019
72019
Activity of the poly (A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain
JM Wheeler, P McMillan, TJ Strovas, NF Liachko, A Amlie-Wolf, RL Kow, ...
Science Translational Medicine 11 (523), 2019
52019
SparkINFERNO: A scalable high-throughput pipeline for inferring molecular mechanisms of non-coding genetic variants
PP Kuksa, CY Lee, A Amlie-Wolf, P Gangadharan, EE Mlynarski, YF Chou, ...
bioRxiv, 2020
22020
HIPPIE2: a method for fine-scale identification of physically interacting chromatin regions
PP Kuksa, A Amlie-Wolf, YC Hwang, O Valladares, BD Gregory, LS Wang
NAR genomics and bioinformatics 2 (2), lqaa022, 2020
2020
INFERRING THE NONCODING REGULATORY MECHANISMS UNDERLYING GENETIC SUSCEPTIBILITY CONTRIBUTED BY DIFFERENT CSF ENDOPHENOTYPES IN AD
YY Leung, A Amlie-Wolf, LS Wang, GD Schellenberg
Alzheimer's & Dementia: The Journal of the Alzheimer's Association 15 (7), P977, 2019
2019
Development and Application of Computational Methods for Inferring the Molecular Mechanisms of Noncoding Genetic Variants
A Amlie-Wolf
University of Pennsylvania, 2019
2019
INFERRING THE MOLECULAR MECHANISMS OF NONCODING AD-ASSOCIATED GENETIC VARIANTS
A Amlie-Wolf, M Tang, BA Dombroski, J Way, N Vrettos, YF Chou, ...
Alzheimer's & Dementia: The Journal of the Alzheimer's Association 14 (7 …, 2018
2018
Molecular phenotyping of human neurons with TDP-43 pathology reveals decondensation of transposable elements
E Liu, J Russ, A Amlie-Wolf, E Lee
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 77 (6), 510-511, 2018
2018
COMPUTATIONAL IDENTIFICATION OF REGULATORY MECHANISMS AFFECTED BY NONCODING VARIANTS ASSOCIATED WITH LATE-ONSET ALZHEIMER'S DISEASE
A Amlie-Wolf, M Tang, J King, BA Dombroski, LS Wang, GD Schellenberg
Alzheimer's & Dementia: The Journal of the Alzheimer's Association 12 (7 …, 2016
2016
A Swarm of Salesman: Algorithmic Approaches to Multiagent Modeling
A Amlie-Wolf
Oberlin College, 2013
2013
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Articles 1–19