Ubiquitin signaling: chemistry comes to the rescue SM Mali, SK Singh, E Eid, A Brik Journal of the American Chemical Society 139 (14), 4971-4986, 2017 | 89 | 2017 |
Convergent versus sequential protein synthesis: the case of ubiquitinated and glycosylated H2B M Seenaiah, M Jbara, SM Mali, A Brik Angewandte Chemie 127 (42), 12551-12555, 2015 | 89 | 2015 |
Thioacids mediated selective and mild N-acylation of amines SM Mali, RD Bhaisare, HN Gopi The Journal of organic chemistry 78 (11), 5550-5555, 2013 | 79 | 2013 |
The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag I Sahu, SM Mali, P Sulkshane, C Xu, A Rozenberg, R Morag, MP Sahoo, ... Nature communications 12 (1), 6173, 2021 | 72 | 2021 |
Total chemical synthesis of SUMO-2-Lys63-linked diubiquitin hybrid chains assisted by removable solubilizing tags S Bondalapati, E Eid, SM Mali, C Wolberger, A Brik Chemical science 8 (5), 4027-4034, 2017 | 70 | 2017 |
De novo macrocyclic peptides that specifically modulate Lys48-linked ubiquitin chains M Nawatha, JM Rogers, SM Bonn, I Livneh, B Lemma, SM Mali, ... Nature chemistry 11 (7), 644-652, 2019 | 69 | 2019 |
Synthetic uncleavable ubiquitinated proteins dissect proteasome deubiquitination and degradation, and highlight distinctive fate of tetraubiquitin SK Singh, I Sahu, SM Mali, HP Hemantha, O Kleifeld, MH Glickman, ... Journal of the American Chemical Society 138 (49), 16004-16015, 2016 | 62 | 2016 |
Copper (II) mediated facile and ultra fast peptide synthesis in methanol SM Mali, SV Jadhav, HN Gopi Chemical communications 48 (56), 7085-7087, 2012 | 56 | 2012 |
Protein ubiquitination via dehydroalanine: development and insights into the diastereoselective 1, 4-addition step R Meledin, SM Mali, SK Singh, A Brik Organic & biomolecular chemistry 14 (21), 4817-4823, 2016 | 51 | 2016 |
Diverse fate of ubiquitin chain moieties: The proximal is degraded with the target, and the distal protects the proximal from removal and recycles H Sun, SM Mali, SK Singh, R Meledin, A Brik, YT Kwon, ... Proceedings of the National Academy of Sciences 116 (16), 7805-7812, 2019 | 49 | 2019 |
Activity‐Based Probes Developed by Applying a Sequential Dehydroalanine Formation Strategy to Expressed Proteins Reveal a Potential α‐Globin‐Modulating Deubiquitinase R Meledin, SM Mali, O Kleifeld, A Brik Angewandte Chemie 130 (20), 5747-5751, 2018 | 45 | 2018 |
Thioacetic Acid/NaSH-Mediated Synthesis of N-Protected Amino Thioacids and Their Utility in Peptide Synthesis SM Mali, HN Gopi The Journal of Organic Chemistry 79 (6), 2377-2383, 2014 | 40 | 2014 |
Synthesis of α, β-unsaturated γ-amino esters with unprecedented high (E)-stereoselectivity and their conformational analysis in peptides SM Mali, A Bandyopadhyay, SV Jadhav, MG Kumar, HN Gopi Organic & Biomolecular Chemistry 9 (19), 6566-6574, 2011 | 38 | 2011 |
Tin (II) chloride assisted synthesis of N-protected γ-amino β-keto esters through semipinacol rearrangement A Bandyopadhyay, N Agrawal, SM Mali, SV Jadhav, HN Gopi Organic & Biomolecular Chemistry 8 (21), 4855-4860, 2010 | 28 | 2010 |
Blocking SHH/Patched interaction triggers tumor growth inhibition through Patched-induced apoptosis PA Bissey, P Mathot, C Guix, M Jasmin, I Goddard, C Costechareyre, ... Cancer research 80 (10), 1970-1980, 2020 | 23 | 2020 |
HBTU mediated 1-hydroxybenzotriazole (HOBt) conjugate addition: synthesis and stereochemical analysis of β-benzotriazole N-oxide substituted γ-amino acids and hybrid peptides SM Mali, MG Kumar, MM Katariya, HN Gopi Organic & Biomolecular Chemistry 12 (42), 8462-8472, 2014 | 23 | 2014 |
Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors SS Chavali, SM Mali, JL Jenkins, R Fasan, JE Wedekind Journal of Biological Chemistry 295 (49), 16470-16486, 2020 | 21 | 2020 |
Total chemical synthesis of ester-linked ubiquitinated proteins unravels their behavior with deubiquitinases H Sun, R Meledin, SM Mali, A Brik Chemical Science 9 (6), 1661-1665, 2018 | 21 | 2018 |
Synthesis and structural investigations of functionalizable hybrid β-hairpin A Bandyopadhyay, SM Mali, P Lunawat, KMP Raja, HN Gopi Organic Letters 13 (17), 4482-4485, 2011 | 20 | 2011 |
A facile synthesis and crystallographic analysis of N-protected β-amino alcohols and short peptaibols SV Jadhav, A Bandyopadhyay, SN Benke, SM Mali, HN Gopi Organic & biomolecular chemistry 9 (11), 4182-4187, 2011 | 17 | 2011 |