Zwitterionic gel encapsulation promotes protein stability, enhances pharmacokinetics, and reduces immunogenicity P Zhang, F Sun, C Tsao, S Liu, P Jain, A Sinclair, HC Hung, T Bai, K Wu, ... Proceedings of the National Academy of Sciences 112 (39), 12046-12051, 2015 | 277 | 2015 |
Expansion of primitive human hematopoietic stem cells by culture in a zwitterionic hydrogel T Bai, J Li, A Sinclair, S Imren, F Merriam, F Sun, MB O’Kelly, C Nourigat, ... Nature medicine 25 (10), 1566-1575, 2019 | 205 | 2019 |
Hierarchical zwitterionic modification of a SERS substrate enables real-time drug monitoring in blood plasma F Sun, HC Hung, A Sinclair, P Zhang, T Bai, DD Galvan, P Jain, B Li, ... Nature communications 7 (1), 13437, 2016 | 192 | 2016 |
Zwitterionic fusion in hydrogels and spontaneous and time-independent self-healing under physiological conditions T Bai, S Liu, F Sun, A Sinclair, L Zhang, Q Shao, S Jiang Biomaterials 35 (13), 3926-3933, 2014 | 136 | 2014 |
Self‐healing zwitterionic microgels as a versatile platform for malleable cell constructs and injectable therapies A Sinclair, MB O'Kelly, T Bai, HC Hung, P Jain, S Jiang Advanced Materials 30 (39), 1803087, 2018 | 124 | 2018 |
Ultra-low fouling and high antibody loading zwitterionic hydrogel coatings for sensing and detection in complex media YN Chou, F Sun, HC Hung, P Jain, A Sinclair, P Zhang, T Bai, Y Chang, ... Acta biomaterialia 40, 31-37, 2016 | 88 | 2016 |
High-strength and fibrous capsule–resistant zwitterionic elastomers D Dong, C Tsao, HC Hung, F Yao, C Tang, L Niu, J Ma, J MacArthur, ... Science advances 7 (1), eabc5442, 2021 | 86 | 2021 |
Restraint of the differentiation of mesenchymal stem cells by a nonfouling zwitterionic hydrogel T Bai, F Sun, L Zhang, A Sinclair, S Liu, JR Ella‐Menye, Y Zheng, S Jiang Angewandte Chemie 126 (47), 12943-12948, 2014 | 85 | 2014 |
Zwitterionic nanocages overcome the efficacy loss of biologic drugs B Li, Z Yuan, P Zhang, A Sinclair, P Jain, K Wu, C Tsao, J Xie, HC Hung, ... Advanced Materials 30 (14), 1705728, 2018 | 75 | 2018 |
A Coating‐Free Nonfouling Polymeric Elastomer HC Hung, P Jain, P Zhang, F Sun, A Sinclair, T Bai, B Li, K Wu, C Tsao, ... Advanced Materials 29 (31), 1700617, 2017 | 70 | 2017 |
EKylation: addition of an alternating-charge peptide stabilizes proteins EJ Liu, A Sinclair, AJ Keefe, BL Nannenga, BL Coyle, F Baneyx, S Jiang Biomacromolecules 16 (10), 3357-3361, 2015 | 64 | 2015 |
Engineering buffering and hydrolytic or photolabile charge shifting in a polycarboxybetaine ester gene delivery platform A Sinclair, T Bai, LR Carr, JR Ella-Menye, L Zhang, S Jiang Biomacromolecules 14 (5), 1587-1593, 2013 | 51 | 2013 |
Directed neural stem cell differentiation on polyaniline-coated high strength hydrogels B Xu, T Bai, A Sinclair, W Wang, Q Wu, F Gao, H Jia, S Jiang, W Liu Materials Today Chemistry 1, 15-22, 2016 | 49 | 2016 |
Butyrylcholinesterase nanocapsule as a long circulating bioscavenger with reduced immune response P Zhang, P Jain, C Tsao, A Sinclair, F Sun, HC Hung, T Bai, K Wu, S Jiang Journal of controlled release 230, 73-78, 2016 | 46 | 2016 |
Hydrolytic cationic ester microparticles for highly efficient DNA vaccine delivery L Zhang, A Sinclair, Z Cao, JR Ella‐Menye, X Xu, LR Carr, SH Pun, ... Small 9 (20), 3439-3444, 2013 | 40 | 2013 |
Zwitterionic hydrogels based on a degradable disulfide carboxybetaine cross-linker P Jain, HC Hung, B Li, J Ma, D Dong, X Lin, A Sinclair, P Zhang, ... Langmuir 35 (5), 1864-1871, 2018 | 37 | 2018 |
Harnessing isomerization-mediated manipulation of nonspecific cell/matrix interactions to reversibly trigger and suspend stem cell differentiation T Bai, A Sinclair, F Sun, P Jain, HC Hung, P Zhang, JR Ella-Menye, W Liu, ... Chemical Science 7 (1), 333-338, 2016 | 35 | 2016 |
Functionalized zwitterionic and mixed charge polymers, related hydrogels, and methods for their use S Jiang, T Bai, HS Sundaram, AW Sinclair, JR Ella-Menye, P Jain US Patent 10,828,398, 2020 | 16 | 2020 |
Hierarchical design of a polymeric nanovehicle for efficient tumor regression and imaging J An, Q Guo, P Zhang, A Sinclair, Y Zhao, X Zhang, K Wu, F Sun, ... Nanoscale 8 (17), 9318-9327, 2016 | 14 | 2016 |
Functionalized Zwitterionic and mixed charge polymers, related hydrogels, and methods for their use S Jiang, T Bai, HS Sundaram, AW Sinclair, JR Ella-Menye, P Jain US Patent 10,272,180, 2019 | 12 | 2019 |