|Expression of pro-and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors|
DG Nowak, J Woolard, EM Amin, O Konopatskaya, MA Saleem, ...
Journal of Cell Science 121 (20), 3487-3495, 2008
|Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms a novel therapeutic strategy for angiogenesis|
DG Nowak, EM Amin, ES Rennel, C Hoareau-Aveilla, M Gammons, ...
Journal of Biological Chemistry 285 (8), 5532-5540, 2010
|WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing|
EM Amin, S Oltean, J Hua, MVR Gammons, M Hamdollah-Zadeh, ...
Cancer Cell 20 (6), 768-780, 2011
|Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression|
M Chen, CP Pratt, ME Zeeman, N Schultz, BS Taylor, A O'Neill, ...
Cancer Cell 20 (2), 173-186, 2011
|Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization|
S Senturk, NH Shirole, DG Nowak, V Corbo, A Vaughan, DA Tuveson, ...
Nature Communications 8, doi:10.1038/ncomms14370, 2017
|Overexpression of VEGF165b in podocytes reduces glomerular permeability|
Y Qiu, J Ferguson, S Oltean, CR Neal, A Kaura, H Bevan, E Wood, ...
Journal of the American Society of Nephrology 21 (9), 1498-1509, 2010
|Myc drives Pten/ p53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression via Phlpp2.|
DG Nowak, H Cho, T Herzka, K Watrud, DV DeMarco, VM Wang, ...
Cancer Discovery, 2015
|Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms|
J Woolard, W Vousden, SJ Moss, A Krishnakumar, MVR Gammons, ...
Chemical Science 2 (2), 273-278, 2011
|Molecular pathways: PI3K pathway phosphatases as biomarkers for cancer prognosis and therapy|
M Chen, DG Nowak, LC Trotman
Clinical Cancer Research 20 (12), 3057-3063, 2014
|The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein|
M Chen, DG Nowak, N Narula, B Robinson, K Watrud, A Ambrico, ...
Journal of Cell Biology 216 (3), 641-656, 2017
|Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output|
G Reyes, M Niederst, K Cohen-Katsenelson, JD Stender, MT Kunkel, ...
Proceedings of the National Academy of Sciences 111 (38), E3957-E3965, 2014
|The PHLPP2 phosphatase is a druggable driver of prostate cancer progression|
DG Nowak, KC Katsenelson, KE Watrud, M Chen, G Mathew, ...
Journal of Cell Biol 218 (6), 1943-1957, 2019
|Utility of single cell genomics in diagnostic evaluation of prostate cancer|
J Alexander, J Kendall, J McIndoo, L Rodgers, R Aboukhalil, D Levy, ...
Cancer Research, 2017
|Prostate cancer genetic-susceptibility locus on chromosome 20q13 is amplified and coupled to androgen receptor-regulation in metastatic tumors|
DP Labbé, DG Nowak, G Deblois, L Lessard, V Giguère, LC Trotman, ...
Molecular Cancer Research 12 (2), 184-189, 2014