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| The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis P Xie, M Zhang, S He, K Lu, Y Chen, G Xing, Y Lu, P Liu, Y Li, S Wang, ... Nature communications 5 (1), 3733, 2014 | 188 | 2014 |
| The unfolded protein response mediator PERK governs myeloid cell-driven immunosuppression in tumors through inhibition of STING signaling E Mohamed, RA Sierra, J Trillo-Tinoco, Y Cao, P Innamarato, KK Payne, ... Immunity 52 (4), 668-682. e7, 2020 | 123 | 2020 |
| Rhamnetin induces sensitization of hepatocellular carcinoma cells to a small molecular kinase inhibitor or chemotherapeutic agents H Jia, Q Yang, T Wang, Y Cao, Q Jiang, H Sun, M Hou, Y Yang, F Feng Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (7), 1417-1430, 2016 | 122 | 2016 |
| A Smurf1 tale: function and regulation of an ubiquitin ligase in multiple cellular networks Y Cao, L Zhang Cellular and molecular life sciences 70, 2305-2317, 2013 | 101 | 2013 |
| ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression Y Cao, J Trillo-Tinoco, RA Sierra, C Anadon, W Dai, E Mohamed, L Cen, ... Nature communications 10 (1), 1280, 2019 | 99 | 2019 |
| Pregnane X receptor mediates sorafenib resistance in advanced hepatocellular carcinoma F Feng, Q Jiang, S Cao, Y Cao, R Li, L Shen, H Zhu, T Wang, L Sun, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (4), 1017-1030, 2018 | 94 | 2018 |
| Endoplasmic reticulum stress regulates tumor growth and anti-tumor immunity: a promising opportunity for cancer immunotherapy E Mohamed, Y Cao, PC Rodriguez Cancer Immunology, Immunotherapy 66, 1069-1078, 2017 | 87 | 2017 |
| SREBP-1 inhibitor Betulin enhances the antitumor effect of Sorafenib on hepatocellular carcinoma via restricting cellular glycolytic activity F Yin, F Feng, L Wang, X Wang, Z Li, Y Cao Cell death & disease 10 (9), 672, 2019 | 86 | 2019 |
| Selective small molecule compounds increase BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation Y Cao, C Wang, X Zhang, G Xing, K Lu, Y Gu, F He, L Zhang Scientific reports 4 (1), 4965, 2014 | 81 | 2014 |
| ETS-1 induces Sorafenib-resistance in hepatocellular carcinoma cells via regulating transcription factor activity of PXR Z Shao, Y Li, W Dai, H Jia, Y Zhang, Q Jiang, Y Chai, X Li, H Sun, R Yang, ... Pharmacological Research 135, 188-200, 2018 | 71 | 2018 |
| Muscle Yap is a regulator of neuromuscular junction formation and regeneration K Zhao, C Shen, Y Lu, Z Huang, L Li, CD Rand, J Pan, XD Sun, Z Tan, ... Journal of Neuroscience 37 (13), 3465-3477, 2017 | 71 | 2017 |
| Enzymatic activity of the scaffold protein rapsyn for synapse formation L Li, Y Cao, H Wu, X Ye, Z Zhu, G Xing, C Shen, A Barik, B Zhang, X Xie, ... Neuron 92 (5), 1007-1019, 2016 | 68 | 2016 |
| AMPK alpha-1 intrinsically regulates the function and differentiation of tumor myeloid-derived suppressor cells J Trillo-Tinoco, RA Sierra, E Mohamed, Y Cao, Á de Mingo-Pulido, ... Cancer research 79 (19), 5034-5047, 2019 | 41 | 2019 |
| Polyphenol-rich extract induces apoptosis with immunogenic markers in melanoma cells through the ER stress-associated kinase PERK K Prieto, Y Cao, E Mohamed, J Trillo-Tinoco, RA Sierra, C Urueña, ... Cell death discovery 5 (1), 134, 2019 | 37 | 2019 |
| The Nedd8 non-covalent binding region in the Smurf HECT domain is critical to its ubiquitn ligase function S He, Y Cao, P Xie, G Dong, L Zhang Scientific Reports 7 (1), 41364, 2017 | 24 | 2017 |
| A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome G Xing, H Jing, L Zhang, Y Cao, L Li, K Zhao, Z Dong, W Chen, H Wang, ... Elife 8, e49180, 2019 | 22 | 2019 |
| Pharmaceutical perspectives of HECT-type ubiquitin ligase Smurf1 Y Cao, L Zhang Current pharmaceutical design 19 (18), 3226-3233, 2013 | 17 | 2013 |
| Linking skeletal muscle aging with osteoporosis by lamin A/C deficiency L Xiong, K Zhao, Y Cao, HH Guo, JX Pan, X Yang, X Ren, L Mei, ... PLoS Biology 18 (6), e3000731, 2020 | 14 | 2020 |
| Selective compounds enhance osteoblastic activity by targeting HECT domain of ubiquitin ligase Smurf1 Y Zhang, C Wang, Y Cao, Y Gu, L Zhang Oncotarget 8 (31), 50521, 2017 | 14 | 2017 |
Lin MeiChinese Institutes for Medical Research, Beijing (CIMR)Verified email at cimrbj.ac.cn
