Lin28 sustains early renal progenitors and induces Wilms tumor A Urbach, A Yermalovich, J Zhang, CS Spina, H Zhu, AR Perez-Atayde, ... Genes & development 28 (9), 971-982, 2014 | 179 | 2014 |
The yin and yang of kidney development and Wilms’ tumors P Hohenstein, K Pritchard-Jones, J Charlton Genes & development 29 (5), 467-482, 2015 | 163 | 2015 |
Genetic determinants and epigenetic effects of pioneer-factor occupancy J Donaghey, S Thakurela, J Charlton, JS Chen, ZD Smith, H Gu, R Pop, ... Nature genetics 50 (2), 250-258, 2018 | 162 | 2018 |
Genome-wide tracking of dCas9-methyltransferase footprints C Galonska, J Charlton, AL Mattei, J Donaghey, K Clement, H Gu, ... Nature communications 9 (1), 597, 2018 | 146 | 2018 |
Circadian entrainment triggers maturation of human in vitro islets JR Alvarez-Dominguez, J Donaghey, N Rasouli, JHR Kenty, A Helman, ... Cell stem cell 26 (1), 108-122. e10, 2020 | 143 | 2020 |
Bilateral Wilms tumour: a review of clinical and molecular features J Charlton, S Irtan, C Bergeron, K Pritchard-Jones Expert reviews in molecular medicine 19, e8, 2017 | 117 | 2017 |
The RNA helicase DDX6 controls cellular plasticity by modulating P-body homeostasis B Di Stefano, EC Luo, C Haggerty, S Aigner, J Charlton, J Brumbaugh, ... Cell stem cell 25 (5), 622-638. e13, 2019 | 92 | 2019 |
TETs compete with DNMT3 activity in pluripotent cells at thousands of methylated somatic enhancers J Charlton, EJ Jung, AL Mattei, N Bailly, J Liao, EJ Martin, P Giesselmann, ... Nature genetics 52 (8), 819-827, 2020 | 90 | 2020 |
Global delay in nascent strand DNA methylation J Charlton, TL Downing, ZD Smith, H Gu, K Clement, R Pop, V Akopian, ... Nature structural & molecular biology 25 (4), 327-332, 2018 | 69 | 2018 |
Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour J Charlton, RD Williams, NJ Sebire, S Popov, G Vujanic, T Chagtai, ... Genome medicine 7, 1-11, 2015 | 55 | 2015 |
Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo J Brumbaugh, IS Kim, F Ji, AJ Huebner, B Di Stefano, BA Schwarz, ... Nature cell biology 21 (11), 1449-1461, 2019 | 50 | 2019 |
Methylome analysis identifies a Wilms tumor epigenetic biomarker detectable in blood J Charlton, RD Williams, M Weeks, NJ Sebire, S Popov, G Vujanic, ... Genome Biology 15, 1-8, 2014 | 43 | 2014 |
The IGF signalling pathway in Wilms tumours-A report from the ENCCA Renal Tumours Biology-driven drug development workshop M Maschietto, J Charlton, D Perotti, P Radice, JI Geller, K Pritchard-Jones, ... Oncotarget 5 (18), 8014, 2014 | 34 | 2014 |
Targets and genomic constraints of ectopic Dnmt3b expression Y Zhang, J Charlton, R Karnik, I Beerman, ZD Smith, H Gu, P Boyle, X Mi, ... Elife 7, e40757, 2018 | 32 | 2018 |
Netrin-1 promotes naive pluripotency through Neo1 and Unc5b co-regulation of Wnt and MAPK signalling A Huyghe, G Furlan, D Ozmadenci, C Galonska, J Charlton, X Gaume, ... Nature Cell Biology 22 (4), 389-400, 2020 | 30 | 2020 |
WT1 mutation in childhood cancer J Charlton, K Pritchard-Jones The Wilms' Tumor (WT1) Gene: Methods and Protocols, 1-14, 2016 | 27 | 2016 |
Biomarkers to detect Wilms tumors in pediatric patients: where are we now? J Charlton, V Pavasovic, K Pritchard-Jones Future Oncology 11 (15), 2221-2234, 2015 | 27 | 2015 |
Symmetrical enchondromatosis is associated with duplication of 12p11.23 to 12p11.22 including PTHLH M Collinson, SJ Leonard, J Charlton, JA Crolla, C Silve, CM Hall, ... American journal of medical genetics Part A 152 (12), 3124-3128, 2010 | 22 | 2010 |
Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells M Yagi, F Ji, J Charlton, S Cristea, K Messemer, N Horwitz, B Di Stefano, ... Genes & Development 35 (17-18), 1209-1228, 2021 | 20 | 2021 |
Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression AM Tsankov, MH Wadsworth, V Akopian, J Charlton, SJ Allon, ... Development 146 (19), dev174722, 2019 | 11 | 2019 |