| Comparative evaluation of 11 scoring functions for molecular docking R Wang, Y Lu, S Wang Journal of medicinal chemistry 46 (12), 2287-2303, 2003 | 1089 | 2003 |
| The PDBbind database: Collection of binding affinities for protein− ligand complexes with known three-dimensional structures R Wang, X Fang, Y Lu, S Wang Journal of medicinal chemistry 47 (12), 2977-2980, 2004 | 1052 | 2004 |
| Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer IA Asangani, VL Dommeti, X Wang, R Malik, M Cieslik, R Yang, ... Nature 510 (7504), 278-282, 2014 | 981 | 2014 |
| The PDBbind database: methodologies and updates R Wang, X Fang, Y Lu, CY Yang, S Wang Journal of medicinal chemistry 48 (12), 4111-4119, 2005 | 847 | 2005 |
| Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2− p53 interaction K Ding, Y Lu, Z Nikolovska-Coleska, G Wang, S Qiu, S Shangary, W Gao, ... Journal of medicinal chemistry 49 (12), 3432-3435, 2006 | 834 | 2006 |
| Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition S Shangary, D Qin, D McEachern, M Liu, RS Miller, S Qiu, ... Proceedings of the National Academy of Sciences 105 (10), 3933-3938, 2008 | 813 | 2008 |
| Structure-based design of potent non-peptide MDM2 inhibitors K Ding, Y Lu, Z Nikolovska-Coleska, S Qiu, Y Ding, W Gao, J Stuckey, ... Journal of the American Chemical Society 127 (29), 10130-10131, 2005 | 767 | 2005 |
| Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy S Shangary, S Wang Annual review of pharmacology and toxicology 49, 223-241, 2009 | 744 | 2009 |
| Development and optimization of a binding assay for the XIAP BIR3 domain using fluorescence polarization Z Nikolovska-Coleska, R Wang, X Fang, H Pan, Y Tomita, P Li, PP Roller, ... Analytical biochemistry 332 (2), 261-273, 2004 | 630 | 2004 |
| A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells H Song, R Wang, S Wang, J Lin Proceedings of the National Academy of Sciences 102 (13), 4700-4705, 2005 | 626 | 2005 |
| Small-molecule inhibitors of the MDM2–p53 protein–protein interaction (MDM2 Inhibitors) in clinical trials for cancer treatment: miniperspective Y Zhao, A Aguilar, D Bernard, S Wang Journal of medicinal chemistry 58 (3), 1038-1052, 2015 | 526 | 2015 |
| Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three … Z Nikolovska-Coleska, L Xu, Z Hu, Y Tomita, P Li, PP Roller, R Wang, ... Journal of medicinal chemistry 47 (10), 2430-2440, 2004 | 474 | 2004 |
| Discovery of small-molecule inhibitors of Bcl-2 through structure-based computer screening IJ Enyedy, Y Ling, K Nacro, Y Tomita, X Wu, Y Cao, R Guo, B Li, X Zhu, ... Journal of medicinal chemistry 44 (25), 4313-4324, 2001 | 465 | 2001 |
| Targeting the MDM2-p53 interaction for cancer therapy S Shangary, S Wang Clinical Cancer Research 14 (17), 5318-5324, 2008 | 423 | 2008 |
| A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo L Bai, H Zhou, R Xu, Y Zhao, K Chinnaswamy, D McEachern, J Chen, ... Cancer cell 36 (5), 498-511. e17, 2019 | 420 | 2019 |
| Coumarin-based inhibitors of HIV integrase H Zhao, N Neamati, H Hong, A Mazumder, S Wang, S Sunder, GWA Milne, ... Journal of medicinal chemistry 40 (2), 242-249, 1997 | 406 | 1997 |
| Computer automated log P calculations based on an extended group contribution approach G Klopman, JY Li, S Wang, M Dimayuga Journal of Chemical Information and Computer Sciences 34 (4), 752-781, 1994 | 403 | 1994 |
| Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins G Wang, Z Nikolovska-Coleska, CY Yang, R Wang, G Tang, J Guo, ... Journal of medicinal chemistry 49 (21), 6139-6142, 2006 | 379 | 2006 |
| How does consensus scoring work for virtual library screening? An idealized computer experiment R Wang, S Wang Journal of Chemical Information and Computer Sciences 41 (5), 1422-1426, 2001 | 373 | 2001 |
| Discovery of a small-molecule degrader of bromodomain and extra-terminal (BET) proteins with picomolar cellular potencies and capable of achieving tumor regression B Zhou, J Hu, F Xu, Z Chen, L Bai, E Fernandez-Salas, M Lin, L Liu, ... Journal of medicinal chemistry 61 (2), 462-481, 2018 | 358 | 2018 |
Renxiao WangFudan UniversityVerified email at fudan.edu.cn
Renxiao WangFudan UniversityVerified email at fudan.edu.cn