| CD28 costimulation: from mechanism to therapy JH Esensten, YA Helou, G Chopra, A Weiss, JA Bluestone Immunity 44 (5), 973-988, 2016 | 812 | 2016 |
| Reprogramming human T cell function and specificity with non-viral genome targeting TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ... Nature 559 (7714), 405-409, 2018 | 750 | 2018 |
| Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes SA McClymont, AL Putnam, MR Lee, JH Esensten, W Liu, MA Hulme, ... The Journal of Immunology 186 (7), 3918-3926, 2011 | 514 | 2011 |
| Intrinsic and extrinsic control of peripheral T‐cell tolerance by costimulatory molecules of the CD28/B7 family H Bour‐Jordan, JH Esensten, M Martinez‐Llordella, C Penaranda, ... Immunological reviews 241 (1), 180-205, 2011 | 472 | 2011 |
| Magnitude and kinetics of anti–severe acute respiratory syndrome coronavirus 2 antibody responses and their relationship to disease severity KL Lynch, JD Whitman, NP Lacanienta, EW Beckerdite, SA Kastner, ... Clinical Infectious Diseases 72 (2), 301-308, 2021 | 246 | 2021 |
| Regulatory T-cell therapy for autoimmune and autoinflammatory diseases: the next frontier JH Esensten, YD Muller, JA Bluestone, Q Tang Journal of Allergy and Clinical Immunology 142 (6), 1710-1718, 2018 | 164 | 2018 |
| Regulatory T cells as therapeutic targets in rheumatoid arthritis JH Esensten, D Wofsy, JA Bluestone Nature Reviews Rheumatology 5 (10), 560-565, 2009 | 139 | 2009 |
| microRNA-17–92 regulates IL-10 production by regulatory T cells and control of experimental autoimmune encephalomyelitis D de Kouchkovsky, JH Esensten, WL Rosenthal, MM Morar, JA Bluestone, ... The Journal of Immunology 191 (4), 1594-1605, 2013 | 133 | 2013 |
| The effect of low-dose IL-2 and Treg adoptive cell therapy in patients with type 1 diabetes S Dong, KJ Hiam-Galvez, CT Mowery, KC Herold, SE Gitelman, ... JCI insight 6 (18), 2021 | 109 | 2021 |
| CD28-inducible transcription factor DEC1 is required for efficient autoreactive CD4+ T cell response M Martínez-Llordella, JH Esensten, SL Bailey-Bucktrout, RH Lipsky, ... Journal of Experimental Medicine 210 (8), 1603-1619, 2013 | 108 | 2013 |
| T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function JH Esensten, MR Lee, LH Glimcher, JA Bluestone The Journal of Immunology 183 (1), 75-82, 2009 | 89 | 2009 |
| NFAT5 binds to the TNF promoter distinctly from NFATp, c, 3 and 4, and activates TNF transcription during hypertonic stress alone JH Esensten, AV Tsytsykova, C Lopez-Rodriguez, FA Ligeiro, A Rao, ... Nucleic acids research 33 (12), 3845-3854, 2005 | 83 | 2005 |
| High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails BR Shy, VS Vykunta, A Ha, A Talbot, TL Roth, DN Nguyen, WG Pfeifer, ... Nature biotechnology 41 (4), 521-531, 2023 | 82 | 2023 |
| Engineering therapeutic T cells: from synthetic biology to clinical trials JH Esensten, JA Bluestone, WA Lim Annual Review of Pathology: Mechanisms of Disease 12, 305-330, 2017 | 67 | 2017 |
| Cdk8 deletion in the ApcMin murine tumour model represses EZH2 activity and accelerates tumourigenesis ML McCleland, TM Soukup, SD Liu, JH Esensten, F de Sousa e Melo, ... The Journal of pathology 237 (4), 508-519, 2015 | 64 | 2015 |
| Circulating proteolytic signatures of chemotherapy-induced cell death in humans discovered by N-terminal labeling AP Wiita, GW Hsu, CM Lu, JH Esensten, JA Wells Proceedings of the National Academy of Sciences 111 (21), 7594-7599, 2014 | 43 | 2014 |
| Selective decrease of donor-reactive Tregs after liver transplantation limits Treg therapy for promoting allograft tolerance in humans Q Tang, J Leung, Y Peng, A Sanchez-Fueyo, JJ Lozano, A Lam, K Lee, ... Science translational medicine 14 (669), eabo2628, 2022 | 28 | 2022 |
| Outcomes after ultramassive transfusion in the modern era: an Eastern Association for the Surgery of Trauma multicenter study ZA Matthay, ZJ Hellmann, RA Callcut, EC Matthay, B Nunez-Garcia, ... Journal of Trauma and Acute Care Surgery 91 (1), 24-33, 2021 | 28 | 2021 |
| Hybrid ssDNA repair templates enable high yield genome engineering in primary cells for disease modeling and cell therapy manufacturing BR Shy, V Vykunta, A Ha, TL Roth, A Talbot, DN Nguyen, YY Chen, ... BioRxiv, 2021.09. 02.458799, 2021 | 16 | 2021 |
| Polyclonal regulatory T cell manufacturing under cGMP: a decade of experience J Balcerek, BR Shy, AL Putnam, LM Masiello, A Lares, F Dekovic, ... Frontiers in Immunology 12, 744763, 2021 | 13 | 2021 |
