| POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer YH Huang, O Klingbeil, XY He, XS Wu, G Arun, B Lu, TDD Somerville, ... Genes & development 32 (13-14), 915-928, 2018 | 309 | 2018 |
| LKB1, salt-inducible kinases, and MEF2C are linked dependencies in acute myeloid leukemia Y Tarumoto, B Lu, TDD Somerville, YH Huang, JP Milazzo, XS Wu, ... Molecular cell 69 (6), 1017-1027. e6, 2018 | 130 | 2018 |
| Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma BE Gryder, S Pomella, C Sayers, XS Wu, Y Song, AM Chiarella, S Bagchi, ... Nature genetics 51 (12), 1714-1722, 2019 | 124 | 2019 |
| Structural studies of HHARI/UbcH7∼ Ub reveal unique E2∼ Ub conformational restriction by RBR RING1 KK Dove, JL Olszewski, L Martino, DM Duda, XS Wu, DJ Miller, KH Reiter, ... Structure 25 (6), 890-900. e5, 2017 | 57 | 2017 |
| A transcription factor addiction in leukemia imposed by the MLL promoter sequence B Lu, O Klingbeil, Y Tarumoto, TDD Somerville, YH Huang, Y Wei, ... Cancer Cell 34 (6), 970-981. e8, 2018 | 54 | 2018 |
| ZBED2 is an antagonist of interferon regulatory factor 1 and modifies cell identity in pancreatic cancer TDD Somerville, Y Xu, XS Wu, D Maia-Silva, SK Hur, LMN de Almeida, ... Proceedings of the National Academy of Sciences 117 (21), 11471-11482, 2020 | 42 | 2020 |
| OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage XS Wu, XY He, JJ Ipsaro, YH Huang, JB Preall, D Ng, YT Shue, J Sage, ... Nature 607 (7917), 169-175, 2022 | 41 | 2022 |
| BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma D Laubscher, BE Gryder, BD Sunkel, T Andresson, M Wachtel, S Das, ... Nature Communications 12 (1), 6924, 2021 | 31 | 2021 |
| The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells X Lan, E Khandros, P Huang, SA Peslak, SK Bhardwaj, JD Grevet, ... Blood Advances 3 (10), 1586-1597, 2019 | 31 | 2019 |
| Transcriptional Silencing of ALDH2 Confers a Dependency on Fanconi Anemia Proteins in Acute Myeloid Leukemia Z Yang, XS Wu, Y Wei, SA Polyanskaya, SV Iyer, M Jung, FP Lach, ... Cancer discovery 11 (9), 2300-2315, 2021 | 21 | 2021 |
| BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network X Sun, O Klingbeil, B Lu, C Wu, C Ballon, M Ouyang, XS Wu, Y Jin, ... Nature 613 (7942), 195-202, 2023 | 19 | 2023 |
| ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation Y Gao, XY He, XS Wu, YH Huang, S Toneyan, T Ha, JJ Ipsaro, PK Koo, ... Nature cell biology 25 (2), 298-308, 2023 | 12 | 2023 |
| Sirtuin 6 maintains epithelial STAT6 activity to support intestinal tuft cell development and type 2 immunity X Xiong, C Yang, WQ He, J Yu, Y Xin, X Zhang, R Huang, H Ma, S Xu, Z Li, ... Nature communications 13 (1), 5192, 2022 | 9 | 2022 |
| Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment XY He, Y Gao, D Ng, E Michalopoulou, S George, JM Adrover, L Sun, ... Cancer Cell, 2024 | 5 | 2024 |
| Targeting the mSWI/SNF Complex in POU2F-POU2AF Transcription Factor-Driven Malignancies T He, L Xiao, Y Qiao, O Klingbeil, E Young, XS Wu, R Mannan, ... bioRxiv, 2024.01. 22.576669, 2024 | 1 | 2024 |
| IκBζ is a dual-use coactivator of NF-κB and POU transcription factors A Alpsoy, XS Wu, S Pal, O Klingbeil, P Kumar, O El Demerdash, ... Molecular Cell, 2024 | | 2024 |
| Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer L Duplaquet, K So, AW Ying, X Li, Y Li, X Qiu, R Li, S Singh, XS Wu, Q Liu, ... bioRxiv, 2024 | | 2024 |
| Made to order tuft cells by an OCA-T1 isoform switch XS Wu, CR Vakoc Science Immunology 8 (83), eadh3123, 2023 | | 2023 |
| p73 activates transcriptional signatures of basal lineage identity and ciliogenesis in pancreatic ductal adenocarcinoma SK Hur, TDD Somerville, XS Wu, D Maia-Silva, OE Demerdash, ... bioRxiv, 2023 | | 2023 |
| A pliable ERα cistrome evades therapy XS Wu, CR Vakoc Nature Cell Biology 22 (6), 619-620, 2020 | | 2020 |
Christopher VakocCold Spring Harbor LaboratoryVerified email at cshl.edu
