| Cyclic nucleotide phosphodiesterases (PDEs): diverse regulators of cyclic nucleotide signals and inviting molecular targets for novel therapeutic agents VC Manganiello, E Degerman Thrombosis and haemostasis 82 (08), 407-411, 1999 | 128 | 1999 |
| Compounds J Bantick, M Cooper, P Thorne, M Perry US Patent 6,342,601, 2002 | 104* | 2002 |
| A synthesis of the C (1)-C (15) segment of tsukubaenolide (FK 506). P Kocienski, M Stocks, D Donald, M Cooper, A Manners Tetrahedron letters 29 (35), 4481-4484, 1988 | 103 | 1988 |
| Optimization of monocarboxylate transporter 1 blockers through analysis and modulation of atropisomer interconversion properties SD Guile, JR Bantick, ME Cooper, DK Donald, C Eyssade, AH Ingall, ... Journal of medicinal chemistry 50 (2), 254-263, 2007 | 70 | 2007 |
| Potent blockers of the monocarboxylate transporter MCT1: novel immunomodulatory compounds SD Guile, JR Bantick, DR Cheshire, ME Cooper, AM Davis, DK Donald, ... Bioorganic & medicinal chemistry letters 16 (8), 2260-2265, 2006 | 70 | 2006 |
| Synthetic FKBP12 ligands. Design and synthesis of pyranose replacements. TN Birkenshaw, MV Caffrey, DE Cladingboel, ME Cooper, DK Donald, ... Bioorganic & Medicinal Chemistry Letters 4 (21), 2501-2506, 1994 | 60 | 1994 |
| Synthesis and study of a non macrocyclic FK506 derivative. SJ Teague, ME Cooper, DK Donald, M Furber Bioorganic & Medicinal Chemistry Letters 4 (13), 1581-1584, 1994 | 60 | 1994 |
| Synthesis and evaluation of dual domain macrocyclic FKBP12 ligands. MV Caffrey, DE Cladingboel, ME Cooper, DK Donald, M Furber, ... Bioorganic & Medicinal Chemistry Letters 4 (21), 2507-2510, 1994 | 57 | 1994 |
| Conversion of 4-cyanomethyl-pyrazole-3-carboxamides into CB1 antagonists with lowered propensity to pass the blood–brain-barrier JM Receveur, A Murray, JM Linget, PK Nørregaard, M Cooper, E Bjurling, ... Bioorganic & medicinal chemistry letters 20 (2), 453-457, 2010 | 56 | 2010 |
| Studies relating to the immunosuppressive activity of FK506 M Furber, ME Cooper, DK Donald Tetrahedron letters 34 (8), 1351-1354, 1993 | 55 | 1993 |
| Compounds D Cheshire, A Cooke, M Cooper, D Donald, M Furber, M Perry, P Thorne US Patent 6,180,635, 2001 | 45 | 2001 |
| Synthesis of FK506-cyclosporin hybrid macrocycles SJ Teague, ME Cooper, MJ Stocks Bioorganic & Medicinal Chemistry Letters 5 (20), 2341-2346, 1995 | 44 | 1995 |
| The hepatic cannabinoid 1 receptor as a modulator of hepatic energy state and food intake ME Cooper, SE Regnell British journal of clinical pharmacology 77 (1), 21-30, 2014 | 29 | 2014 |
| A novel fluorescent monomer for the selective detection of phenols and anilines MA Reppy, ME Cooper, JL Smithers, DL Gin The Journal of Organic Chemistry 64 (11), 4191-4195, 1999 | 27 | 1999 |
| Exploring SAR features in diverse library of 4-cyanomethyl-pyrazole-3-carboxamides suitable for further elaborations as CB1 antagonists M Cooper, JM Receveur, E Bjurling, PK Nørregaard, PA Nielsen, N Sköld, ... Bioorganic & medicinal chemistry letters 20 (1), 26-30, 2010 | 26 | 2010 |
| Design and synthesis of novel fluorescent chemosensors for biologically active molecules ME Cooper, BP Hoag, D Gin Polym. Prepr 38, 209-210, 1997 | 26 | 1997 |
| Thienopyrimidinediones and their use in the modulation of autoimmune disease RH Reynolds, AH Ingall, RT Rasul, SD Guile, ME Cooper US Patent 7,384,950, 2008 | 21 | 2008 |
| Climate change and insurance A Dlugolecki, M Agnew, M Cooper, D Crichton, N Kelly, T Loster, ... Chartered Insurance Institute, London, 2001 | 21 | 2001 |
| A novel class of small molecule agonists with preference for human over mouse TLR4 activation JD Marshall, DS Heeke, E Rao, SK Maynard, D Hornigold, C McCrae, ... PLoS One 11 (10), e0164632, 2016 | 19 | 2016 |
| C10 N-Acyl modified FK-506: A possible hybrid analogue of the transition state of peptidyl-prolyl cis-trans isomerization. DK Donald, ME Cooper, M Furber, E Wells, R Hutchinson, FM Black Tetrahedron letters 32 (10), 1375-1378, 1991 | 17 | 1991 |
