| Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug–drug interactions M Karlgren, A Vildhede, U Norinder, JR Wisniewski, E Kimoto, Y Lai, ... Journal of medicinal chemistry 55 (10), 4740-4763, 2012 | 374 | 2012 |
| In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes JR Wiśniewski, A Vildhede, A Norén, P Artursson Journal of proteomics 136, 234-247, 2016 | 171 | 2016 |
| Hepatic uptake of atorvastatin: influence of variability in transporter expression on uptake clearance and drug-drug interactions A Vildhede, M Karlgren, EK Svedberg, JR Wisniewski, Y Lai, A Norén, ... Drug metabolism and disposition 42 (7), 1210-1218, 2014 | 126 | 2014 |
| Comparative proteomic analysis of human liver tissue and isolated hepatocytes with a focus on proteins determining drug exposure A Vildhede, JR Wisniewski, A Noren, M Karlgren, P Artursson Journal of proteome research 14 (8), 3305-3314, 2015 | 112 | 2015 |
| Quantitative proteomics and mechanistic modeling of transporter‐mediated disposition in nonalcoholic fatty liver disease A Vildhede, E Kimoto, RM Pelis, AD Rodrigues, MVS Varma Clinical Pharmacology & Therapeutics 107 (5), 1128-1137, 2020 | 60 | 2020 |
| Mechanistic modeling of pitavastatin disposition in sandwich-cultured human hepatocytes: a proteomics-informed bottom-up approach A Vildhede, A Mateus, EK Khan, Y Lai, M Karlgren, P Artursson, ... Drug Metabolism and Disposition 44 (4), 505-516, 2016 | 51 | 2016 |
| Primary human hepatocyte spheroid model as a 3D in vitro platform for metabolism studies KP Kanebratt, A Janefeldt, L Vilén, A Vildhede, K Samuelsson, L Milton, ... Journal of Pharmaceutical Sciences 110 (1), 422-431, 2021 | 44 | 2021 |
| Reliable rate measurements for active and passive hepatic uptake using plated human hepatocytes Y Bi, RJ Scialis, S Lazzaro, S Mathialagan, E Kimoto, J Keefer, H Zhang, ... The AAPS journal 19, 787-796, 2017 | 43 | 2017 |
| Organic anion transporter 2 mediates hepatic uptake of tolbutamide, a CYP2C9 probe drug Y Bi, S Mathialagan, L Tylaska, M Fu, J Keefer, A Vildhede, C Costales, ... Journal of Pharmacology and Experimental Therapeutics 364 (3), 390-398, 2018 | 38 | 2018 |
| Comparison of proteomic quantification approaches for hepatic drug transporters: multiplexed global quantitation correlates with targeted proteomic quantitation A Vildhede, C Nguyen, BK Erickson, RC Kunz, R Jones, E Kimoto, ... Drug Metabolism and Disposition 46 (5), 692-696, 2018 | 28 | 2018 |
| Quantification of hepatic organic anion transport proteins OAT2 and OAT7 in human liver tissue and primary hepatocytes A Vildhede, E Kimoto, AD Rodrigues, MVS Varma Molecular pharmaceutics 15 (8), 3227-3235, 2018 | 22 | 2018 |
| In vitro studies with two human organic anion transporters: OAT2 and OAT7 S Mathialagan, C Costales, L Tylaska, E Kimoto, A Vildhede, J Johnson, ... Xenobiotica 48 (10), 1037-1049, 2018 | 20 | 2018 |
| Transporter-mediated disposition, clinical pharmacokinetics and cholestatic potential of glyburide and its primary active metabolites R Li, Y Bi, A Vildhede, RJ Scialis, S Mathialagan, X Yang, LD Marroquin, ... Drug Metabolism and Disposition 45 (7), 737-747, 2017 | 13 | 2017 |
| Gene-by-environment interaction of Bcrp−/− and methionine-and choline-deficient diet–induced nonalcoholic steatohepatitis alters SN-38 disposition EL Toth, H Li, AL Dzierlenga, JD Clarke, A Vildhede, M Goedken, ... Drug Metabolism and Disposition 46 (11), 1478-1486, 2018 | 8 | 2018 |
| Hepatocyte size fractionation allows dissection of human liver zonation M Ölander, C Wegler, I Flörkemeier, A Treyer, N Handin, JM Pedersen, ... Journal of Cellular Physiology 236 (8), 5885-5894, 2021 | 7 | 2021 |
| Does the choice of applied physiologically‐based pharmacokinetics platform matter? A case study on simvastatin disposition and drug–drug interaction L Prieto Garcia, A Lundahl, C Ahlström, A Vildhede, H Lennernäs, ... CPT: Pharmacometrics & Systems Pharmacology 11 (9), 1194-1209, 2022 | 5 | 2022 |
| Understanding Statin‐Roxadustat Drug–Drug‐Disease Interaction Using Physiologically‐Based Pharmacokinetic Modeling J Dong, L Prieto Garcia, Y Huang, W Tang, A Lundahl, M Elebring, ... Clinical Pharmacology & Therapeutics 114 (4), 825-835, 2023 | 4 | 2023 |
| In vitro assessment of the drug–drug interaction potential of verinurad and its metabolites as substrates and inhibitors of metabolizing enzymes and drug transporters VS Gopaul, A Vildhede, TB Andersson, F Erlandsson, CA Lee, ... Journal of Pharmacology and Experimental Therapeutics 378 (2), 108-123, 2021 | 3 | 2021 |
| Characterization of bile acid sulfate conjugates as substrates of human organic anion transporting polypeptides CC Orozco, M Neuvonen, YA Bi, MA Cerny, S Mathialagan, L Tylaska, ... Molecular Pharmaceutics 20 (6), 3020-3032, 2023 | 2 | 2023 |
| Global proteome changes in liver tissue 6 weeks after FOLFOX treatment of colorectal cancer liver metastases J Urdzik, A Vildhede, JR Wiśniewski, F Duraj, U Haglund, P Artursson, ... Proteomes 4 (4), 30, 2016 | 2 | 2016 |
