Diagnostic assessment of deep learning algorithms for detection of lymph node metastases in women with breast cancer BE Bejnordi, M Veta, PJ Van Diest, B Van Ginneken, N Karssemeijer, ... Jama 318 (22), 2199-2210, 2017 | 3317 | 2017 |
Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation S Kurki, K Peltonen, L Latonen, TM Kiviharju, PM Ojala, D Meek, M Laiho Cancer cell 5 (5), 465-475, 2004 | 540 | 2004 |
Cellular UV damage responses—functions of tumor suppressor p53 L Latonen, M Laiho Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1755 (2), 71-89, 2005 | 285 | 2005 |
Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer SE Jalava, A Urbanucci, L Latonen, KK Waltering, B Sahu, OA Jänne, ... Oncogene 31 (41), 4460-4471, 2012 | 266 | 2012 |
Cell cycle arrest and apoptosis provoked by UV radiation‐induced DNA damage are transcriptionally highly divergent responses M Gentile, L Latonen, M Laiho Nucleic acids research 31 (16), 4779-4790, 2003 | 231 | 2003 |
hTERT antagonizes p53-induced apoptosis independently of telomerase activity R Rahman, L Latonen, KG Wiman Oncogene 24 (8), 1320-1327, 2005 | 219 | 2005 |
Androgen regulation of micro‐RNAs in prostate cancer KK Waltering, KP Porkka, SE Jalava, A Urbanucci, PJ Kohonen, ... The Prostate 71 (6), 604-614, 2011 | 199 | 2011 |
Overexpression of androgen receptor enhances the binding of the receptor to the chromatin in prostate cancer A Urbanucci, B Sahu, J Seppälä, A Larjo, LM Latonen, KK Waltering, ... Oncogene 31 (17), 2153-2163, 2012 | 191 | 2012 |
UV-radiation induces dose-dependent regulation of p53 response and modulates p53-HDM2 interaction in human fibroblasts L Latonen, Y Taya, M Laiho Oncogene 20 (46), 6784-6793, 2001 | 169 | 2001 |
Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression L Latonen, E Afyounian, A Jylhä, J Nättinen, U Aapola, M Annala, ... Nature communications 9 (1), 1176, 2018 | 158 | 2018 |
Proteasome inhibitors induce nucleolar aggregation of proteasome target proteins and polyadenylated RNA by altering ubiquitin availability L Latonen, HM Moore, B Bai, S Jäämaa, M Laiho Oncogene 30 (7), 790-805, 2011 | 150 | 2011 |
Quantitative proteomics and dynamic imaging of the nucleolus reveal distinct responses to UV and ionizing radiation HM Moore, B Bai, FM Boisvert, L Latonen, V Rantanen, JC Simpson, ... Molecular & cellular proteomics 10 (10), 2011 | 149 | 2011 |
ANHIR: automatic non-rigid histological image registration challenge J Borovec, J Kybic, I Arganda-Carreras, DV Sorokin, G Bueno, ... IEEE transactions on medical imaging 39 (10), 3042-3052, 2020 | 146 | 2020 |
Phase-to-phase with nucleoli–stress responses, protein aggregation and novel roles of RNA L Latonen Frontiers in cellular neuroscience 13, 151, 2019 | 143 | 2019 |
Redox state of tumor suppressor p53 regulates its sequence-specific DNA binding in DNA-damaged cells by cysteine 277 J Buzek, L Latonen, S Kurki, K Peltonen, M Laiho Nucleic acids research 30 (11), 2340-2348, 2002 | 140 | 2002 |
Cellular stress and DNA damage invoke temporally distinct Mdm2, p53 and PML complexes and damage-specific nuclear relocalization S Kurki, L Latonen, M Laiho Journal of cell science 116 (19), 3917-3925, 2003 | 135 | 2003 |
Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases HML Kallio, R Hieta, L Latonen, A Brofeldt, M Annala, K Kivinummi, ... British journal of cancer 119 (3), 347-356, 2018 | 103 | 2018 |
Transcriptome Sequencing Reveals PCAT5 as a Novel ERG-Regulated Long Noncoding RNA in Prostate Cancer A Ylipää, K Kivinummi, A Kohvakka, M Annala, L Latonen, M Scaravilli, ... Cancer research 75 (19), 4026-4031, 2015 | 87 | 2015 |
Cell cycle control, DNA damage checkpoints and cancer M Laiho, L Latonen Annals of medicine 35 (6), 391-397, 2003 | 81 | 2003 |
Nucleolar aggresomes as counterparts of cytoplasmic aggresomes in proteotoxic stress: Proteasome inhibitors induce nuclear ribonucleoprotein inclusions that accumulate several … L Latonen Bioessays 33 (5), 386-395, 2011 | 69 | 2011 |