Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol L Wrobel, U Topf, P Bragoszewski, S Wiese, ME Sztolsztener, ... Nature 524 (7566), 485-488, 2015 | 393 | 2015 |
Post-translational modifications of Beclin 1 provide multiple strategies for autophagy regulation SM Hill, L Wrobel, DC Rubinsztein Cell Death & Differentiation 26 (4), 617-629, 2019 | 196 | 2019 |
The different autophagy degradation pathways and neurodegeneration A Fleming, M Bourdenx, M Fujimaki, C Karabiyik, GJ Krause, A Lopez, ... Neuron 110 (6), 935-966, 2022 | 183 | 2022 |
Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species U Topf, I Suppanz, L Samluk, L Wrobel, A Böser, P Sakowska, B Knapp, ... Nature communications 9 (1), 324, 2018 | 178 | 2018 |
Mitochondrial protein import: Mia40 facilitates Tim22 translocation into the inner membrane of mitochondria L Wrobel, A Trojanowska, ME Sztolsztener, A Chacinska Molecular Biology of the Cell 24 (5), 543-554, 2013 | 91 | 2013 |
Chatty mitochondria: keeping balance in cellular protein homeostasis U Topf, L Wrobel, A Chacinska Trends in cell biology 26 (8), 577-586, 2016 | 78 | 2016 |
VCP/p97 regulates Beclin-1-dependent autophagy initiation SM Hill, L Wrobel, A Ashkenazi, M Fernandez-Estevez, K Tan, RW Bürli, ... Nature chemical biology 17 (4), 448-455, 2021 | 74 | 2021 |
Presequence recognition by the tom40 channel contributes to precursor translocation into the mitochondrial matrix J Melin, C Schulz, L Wrobel, O Bernhard, A Chacinska, O Jahn, B Schmidt, ... Molecular and Cellular Biology 34 (18), 3473-3485, 2014 | 45 | 2014 |
Mia40 and MINOS act in parallel with Ccs1 in the biogenesis of mitochondrial Sod1 A Varabyova, U Topf, P Kwiatkowska, L Wrobel, M Kaus‐Drobek, ... The FEBS journal 280 (20), 4943-4959, 2013 | 45 | 2013 |
The presence of disulfide bonds reveals an evolutionarily conserved mechanism involved in mitochondrial protein translocase assembly L Wrobel, AM Sokol, M Chojnacka, A Chacinska Scientific Reports 6 (1), 27484, 2016 | 42 | 2016 |
Mendelian neurodegenerative disease genes involved in autophagy E Stamatakou, L Wróbel, SM Hill, C Puri, SM Son, M Fujimaki, Y Zhu, ... Cell discovery 6 (1), 24, 2020 | 37 | 2020 |
Non-canonical translation initiation in yeast generates a cryptic pool of mitochondrial proteins G Monteuuis, A Miścicka, M Świrski, L Zenad, O Niemitalo, L Wrobel, ... Nucleic Acids Research 47 (11), 5777-5791, 2019 | 32 | 2019 |
mTORC2 assembly is regulated by USP9X-mediated deubiquitination of RICTOR L Wrobel, FH Siddiqi, SM Hill, SM Son, C Karabiyik, H Kim, ... Cell Reports 33 (13), 2020 | 21 | 2020 |
Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance L Wrobel, SM Hill, A Djajadikerta, M Fernandez-Estevez, C Karabiyik, ... Nature Communications 13 (1), 4146, 2022 | 13 | 2022 |
Transient siRNA-mediated protein knockdown in mouse followed by feeding/starving cycle and liver tissue analysis L Wrobel, FH Siddiqi, DC Rubinsztein STAR protocols 2 (2), 100500, 2021 | 7 | 2021 |
VCP/p97 modulates PtdIns3P production and autophagy initiation L Wrobel, SM Hill, A Ashkenazi, DC Rubinsztein Autophagy 17 (4), 1052-1053, 2021 | 2 | 2021 |
VCP/p97 regulates Beclin-1-dependent autophagy initiation D Rubinsztein, S Hill, L Wrobel, A Ashkenazi, M Fernandez-Estevez, ... Nature Research, 2021 | 2 | 2021 |
Author Correction: Mendelian neurodegenerative disease genes involved in autophagy E Stamatakou, L Wrobel, SM Hill, C Puri, SM Son, M Fujimaki, Y Zhu, ... Cell Discovery 6, 2020 | 2 | 2020 |
p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol L Wrobel, JL Hoffmann, X Li, DC Rubinsztein Science Advances 10 (18), eadl6082, 2024 | | 2024 |
p37 regulates VCP/p97 nucleocytoplasmic shuttling D Rubinsztein, L Wrobel, JL Hoffmann, X Li American Association for the Advancement of Science, 2024 | | 2024 |