David Frederick
David Frederick
Postdoctoral fellow, Perelman School of Medicine, University of Pennsylvania
Verified email at mail.med.upenn.edu
Title
Cited by
Cited by
Year
SirT1 regulates adipose tissue inflammation
MP Gillum, ME Kotas, DM Erion, R Kursawe, P Chatterjee, KT Nead, ...
Diabetes 60 (12), 3235-3245, 2011
2742011
Effects of sex, strain, and energy intake on hallmarks of aging in mice
SJ Mitchell, J Madrigal-Matute, M Scheibye-Knudsen, E Fang, M Aon, ...
Cell metabolism 23 (6), 1093-1112, 2016
2232016
SGLT2 deletion improves glucose homeostasis and preserves pancreatic β-cell function
MJ Jurczak, HY Lee, AL Birkenfeld, FR Jornayvaz, DW Frederick, ...
Diabetes 60 (3), 890-898, 2011
1912011
Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle
DW Frederick, E Loro, L Liu, A Davila Jr, K Chellappa, IM Silverman, ...
Cell metabolism 24 (2), 269-282, 2016
1802016
A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain
FR Jornayvaz, MJ Jurczak, HY Lee, AL Birkenfeld, DW Frederick, ...
American Journal of Physiology-Endocrinology and Metabolism 299 (5), E808-E815, 2010
1802010
Quantitative analysis of NAD synthesis-breakdown fluxes
L Liu, X Su, WJ Quinn III, S Hui, K Krukenberg, DW Frederick, P Redpath, ...
Cell metabolism 27 (5), 1067-1080. e5, 2018
1542018
Deletion of the Mammalian INDY Homolog Mimics Aspects of Dietary Restriction and Protects against Adiposity and Insulin Resistance in Mice
AL Birkenfeld, HY Lee, F Guebre-Egziabher, TC Alves, MJ Jurczak, ...
Cell metabolism 14 (2), 184-195, 2011
1452011
Deletion of the α-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity
WA Chutkow, AL Birkenfeld, JD Brown, HY Lee, DW Frederick, ...
Diabetes 59 (6), 1424-1434, 2010
1452010
N-acylphosphatidylethanolamine, a gut-derived circulating factor induced by fat ingestion, inhibits food intake
MP Gillum, D Zhang, XM Zhang, DM Erion, RA Jamison, C Choi, J Dong, ...
Cell 135 (5), 813-824, 2008
1422008
Nicotinamide improves aspects of healthspan, but not lifespan, in mice
SJ Mitchell, M Bernier, MA Aon, S Cortassa, EY Kim, EF Fang, ...
Cell metabolism 27 (3), 667-676. e4, 2018
1322018
Apolipoprotein CIII overexpressing mice are predisposed to diet‐induced hepatic steatosis and hepatic insulin resistance
HY Lee, AL Birkenfeld, FR Jornayvaz, MJ Jurczak, S Kanda, V Popov, ...
Hepatology 54 (5), 1650-1660, 2011
1092011
Influence of the hepatic eukaryotic initiation factor 2α (eIF2α) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral …
AL Birkenfeld, HY Lee, S Majumdar, MJ Jurczak, JP Camporez, ...
Journal of Biological Chemistry 286 (42), 36163-36170, 2011
682011
Influence of the hepatic eukaryotic initiation factor 2α (eIF2α) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral …
AL Birkenfeld, HY Lee, S Majumdar, MJ Jurczak, JP Camporez, ...
Journal of Biological Chemistry 286 (42), 36163-36170, 2011
682011
Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism
DW Frederick, JG Davis, A Dávila Jr, B Agarwal, S Michan, MA Puchowicz, ...
Journal of Biological Chemistry 290 (3), 1546-1558, 2015
632015
Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism
DW Frederick, JG Davis, A Dávila Jr, B Agarwal, S Michan, MA Puchowicz, ...
Journal of Biological Chemistry 290 (3), 1546-1558, 2015
632015
Rapamycin blocks induction of the thermogenic program in white adipose tissue
CM Tran, S Mukherjee, L Ye, DW Frederick, M Kissig, JG Davis, ...
Diabetes 65 (4), 927-941, 2016
582016
Accumulation of 3-hydroxytetradecenoic acid: Cause or corollary of glucolipotoxic impairment of pancreatic β-cell bioenergetics?
NM Doliba, Q Liu, C Li, J Chen, P Chen, C Liu, DW Frederick, JA Baur, ...
Molecular metabolism 4 (12), 926-939, 2015
182015
Stable isotope labeling by essential nutrients in cell culture (SILEC) for accurate measurement of nicotinamide adenine dinucleotide metabolism
DW Frederick, S Trefely, A Buas, J Goodspeed, J Singh, C Mesaros, ...
Analyst 142 (23), 4431-4437, 2017
62017
Influence of the hepatic eIF2α ER stress response pathway on insulin mediated ER stress, Hepatic and Peripheral Glucose Metabolism
AL Birkenfeld, HY Lee, S Majumdar, MJ Juzcak, J Camporez, ...
Journal of Biological Chemistry, jbc. M111. 228817, 2011
62011
Rapamycin maintains NAD+/NADH redox homeostasis in muscle cells
Z Zhang, HN Xu, S Li, A Davila Jr, K Chellappa, JG Davis, Y Guan, ...
Aging (Albany NY) 12 (18), 17786, 2020
42020
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