Alex Ng
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A multifunctional AAV-CRISPR-Cas9 and its host response
WL Chew, M Tabebordbar, JKW Cheng, P Mali, EY Wu, AHM Ng, K Zhu, ...
Nature Methods 13 (10), 868-874, 2016
Impaired Autophagy in the Lipid-Storage Disorder Niemann-Pick Type C1 Disease
S Sarkar, B Carroll, Y Buganim, D Maetzel, AHM Ng, JP Cassady, ...
Cell reports 5 (5), 1302-1315, 2013
Rapid neurogenesis through transcriptional activation in human stem cells
V Busskamp, NE Lewis, P Guye, AHM Ng, SL Shipman, SM Byrne, ...
Molecular systems biology 10 (11), 2014
Hul5 HECT ubiquitin ligase plays a major role in the ubiquitylation and turnover of cytosolic misfolded proteins
NN Fang, AHM Ng, V Measday, T Mayor
Nature Cell Biology 13 (11), 1344-1352, 2011
The Yeast Ubr1 Ubiquitin Ligase Participates in a Prominent Pathway That Targets Cytosolic Thermosensitive Mutants for Degradation
F Khosrow-Khavar, NN Fang, AHM Ng, JM Winget, SA Comyn, T Mayor
G3: Genes| Genomes| Genetics 2 (5), 619-628, 2012
System-wide analysis reveals intrinsically disordered proteins are prone to ubiquitylation after misfolding stress
AHM Ng, NN Fang, SA Comyn, J Gsponer, T Mayor
Molecular & Cellular Proteomics 12 (9), 2456-2467, 2013
Enabling large-scale genome editing at repetitive elements by reducing DNA nicking
CJ Smith, O Castanon, K Said, V Volf, P Khoshakhlagh, A Hornick, ...
Nucleic acids research 48 (9), 5183-5195, 2020
A comprehensive library of human transcription factors for cell fate engineering
AHM Ng, P Khoshakhlagh, JER Arias, G Pasquini, K Wang, A Swiersy, ...
Nature Biotechnology, 1-10, 2020
Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA
K Wang, RZ Lin, X Hong, AH Ng, CN Lee, J Neumeyer, G Wang, X Wang, ...
Science Advances 6 (30), eaba7606, 2020
Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency
B Sun, X Yang, F Hou, X Yu, Q Wang, HS Oh, P Raja, JM Pesola, ...
Nature Microbiology, 1-15, 2021
How Low Can It Go? Trends, Benefits and Risks of Expanding the Definition of Hypertension
A Ng, A Tung
UBC Medical Journal 3 (1), 2011
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Articles 1–11