| 5-Lipoxygenase: regulation of expression and enzyme activity O Rådmark, O Werz, D Steinhilber, B Samuelsson Trends in biochemical sciences 32 (7), 332-341, 2007 | 551 | 2007 |
| 5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease O Rådmark, O Werz, D Steinhilber, B Samuelsson Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 496 | 2015 |
| Boswellia serrata: An Overall Assessment of In Vitro, Preclinical, Pharmacokinetic and Clinical Data M Abdel-Tawab, O Werz, M Schubert-Zsilavecz Clinical pharmacokinetics 50, 349-369, 2011 | 402 | 2011 |
| The nuclear receptor for melatonin represses 5-lipoxygenase gene expression in human b lymphocytes (∗) D Steinhilber, M Brungs, O Werz, I Wiesenberg, C Danielsson, JP Kahlen, ... Journal of Biological Chemistry 270 (13), 7037-7040, 1995 | 339 | 1995 |
| Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase D Albert, I Zündorf, T Dingermann, WE Müller, D Steinhilber, O Werz Biochemical pharmacology 64 (12), 1767-1775, 2002 | 338 | 2002 |
| Therapeutic options for 5-lipoxygenase inhibitors O Werz, D Steinhilber Pharmacology & therapeutics 112 (3), 701-718, 2006 | 327 | 2006 |
| Multi-target approach for natural products in inflammation A Koeberle, O Werz Drug discovery today 19 (12), 1871-1882, 2014 | 312 | 2014 |
| Boswellic acids: biological actions and molecular targets D Poeckel, O Werz Current medicinal chemistry 13 (28), 3359-3369, 2006 | 309 | 2006 |
| 5-lipoxygenase: cellular biology and molecular pharmacology O Werz Current Drug Targets-Inflammation & Allergy 1 (1), 23-44, 2002 | 290 | 2002 |
| 5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases O Werz, J Klemm, B Samuelsson, O Rådmark Proceedings of the National Academy of Sciences 97 (10), 5261-5266, 2000 | 282 | 2000 |
| Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity O Werz, J Gerstmeier, S Libreros, X De la Rosa, M Werner, PC Norris, ... Nature communications 9 (1), 59, 2018 | 256 | 2018 |
| Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes O Werz, E Bürkert, B Samuelsson, O Rådmark, D Steinhilber Blood, The Journal of the American Society of Hematology 99 (3), 1044-1052, 2002 | 230 | 2002 |
| ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma C Pergola, G Dodt, A Rossi, E Neunhoeffer, B Lawrenz, H Northoff, ... Proceedings of the National Academy of Sciences 105 (50), 19881-19886, 2008 | 220 | 2008 |
| 5-Lipoxygenase inhibitors: a review of recent developments and patents C Pergola, O Werz Expert opinion on therapeutic patents 20 (3), 355-375, 2010 | 209 | 2010 |
| Inhibition of 5-lipoxygenase product synthesis by natural compounds of plant origin O Werz Planta medica 73 (13), 1331-1357, 2007 | 205 | 2007 |
| Extracellular signal‐regulated kinases phosphorylate 5lipoxygenase and stimulate 5‐lipoxygenase product formation in leukocytes O Werz, E Bürkert, L Fischer, D Szellas, D Dishart, B Samuelsson, ... The FASEB Journal 16 (11), 1441-1443, 2002 | 198 | 2002 |
| Licofelone suppresses prostaglandin E2 formation by interference with the inducible microsomal prostaglandin E2 synthase-1 A Koeberle, U Siemoneit, U Bühring, H Northoff, S Laufer, W Albrecht, ... Journal of Pharmacology and Experimental Therapeutics 326 (3), 975-982, 2008 | 197 | 2008 |
| Development of 5-lipoxygenase inhibitors—lessons from cellular enzyme regulation O Werz, D Steinhilber Biochemical pharmacology 70 (3), 327-333, 2005 | 194 | 2005 |
| Carnosic acid and carnosol potently inhibit human 5-lipoxygenase and suppress pro-inflammatory responses of stimulated human polymorphonuclear leukocytes D Poeckel, C Greiner, M Verhoff, O Rau, L Tausch, C Hörnig, ... Biochemical pharmacology 76 (1), 91-97, 2008 | 183 | 2008 |
| Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2) O Werz, D Szellas, D Steinhilber, O Rådmark Journal of biological chemistry 277 (17), 14793-14800, 2002 | 173 | 2002 |
