SETD2-dependent histone H3K36 trimethylation is required for homologous recombination repair and genome stability SX Pfister, S Ahrabi, LP Zalmas, S Sarkar, F Aymard, CZ Bachrati, ... Cell reports 7 (6), 2006-2018, 2014 | 453 | 2014 |
Inhibiting WEE1 selectively kills histone H3K36me3-deficient cancers by dNTP starvation SX Pfister, E Markkanen, Y Jiang, S Sarkar, M Woodcock, G Orlando, ... Cancer cell 28 (5), 557-568, 2015 | 295 | 2015 |
Marked for death: targeting epigenetic changes in cancer SX Pfister, A Ashworth Nature reviews Drug discovery 16 (4), 241-263, 2017 | 285 | 2017 |
A role for human homologous recombination factors in suppressing microhomology-mediated end joining S Ahrabi, S Sarkar, SX Pfister, G Pirovano, GS Higgins, ACG Porter, ... Nucleic acids research 44 (12), 5743-5757, 2016 | 117 | 2016 |
Can rational combination of ultra-high dose rate FLASH radiotherapy with immunotherapy provide a novel approach to cancer treatment? Y Zhang, Z Ding, JP Perentesis, D Khuntia, SX Pfister, RA Sharma Clinical Oncology 33 (11), 713-722, 2021 | 32 | 2021 |
IGF-1R inhibition induces schedule-dependent sensitization of human melanoma to temozolomide R Ramcharan, T Aleksic, WP Kamdoum, S Gao, SX Pfister, J Tanner, ... Oncotarget 6 (37), 39877, 2015 | 27 | 2015 |
SET-ting the stage for DNA repair DK Jha, SX Pfister, TC Humphrey, BD Strahl Nature structural & molecular biology 21 (8), 655-657, 2014 | 26 | 2014 |
An essential role for dNTP homeostasis following CDK-induced replication stress CC Pai, KF Hsu, SC Durley, A Keszthelyi, SE Kearsey, C Rallis, LK Folkes, ... Journal of cell science 132 (6), jcs226969, 2019 | 24 | 2019 |
Combinatorial immunotherapy induces tumor-infiltrating CD8+ T cells with distinct functional, migratory, and stem-like properties N Van Braeckel-Budimir, JS Dolina, J Wei, X Wang, SH Chen, P Santiago, ... Journal for ImmunoTherapy of Cancer 9 (12), 2021 | 12 | 2021 |
Keys to the kingdom SCK Wong, LS Sasportas, K Richardson, BR Gordon, MKP Jayatunga, ... Nature Biotechnology 33 (3), 232-236, 2015 | 4 | 2015 |
Model selection for the preclinical development of new drug–radiotherapy combinations J Singh, S Hatcher, AA Ku, Z Ding, FY Feng, RA Sharma, SX Pfister Clinical Oncology 33 (11), 694-704, 2021 | 2 | 2021 |
211 A novel synthetic lethal interaction between the histone mark H3K36me3 and checkpoint kinases SX Pfister, E Markkanen, Y Jiang, S Sarkar, V D'Angiolella, G Dianov, ... European Journal of Cancer, 71, 2014 | 1 | 2014 |
Enhanced dose rate/ultra-high dose rate radiation and spatially fractioned radiation therapy G Boivin, M Folkerts, S Pfister, M Vilalta, V Krishnamurthi, RA Sharma US Patent App. 17/950,005, 2024 | | 2024 |
Radiotherapy Shows Synergistic Anti-Tumor Efficacy with Treg Depletion by Reprogramming the Immune-Excluded Tumor Microenvironment Y Zhang, M Vilalta, L Tang, R Sharma, SX Pfister International Journal of Radiation Oncology, Biology, Physics 117 (2), S72, 2023 | | 2023 |
Methods of and apparatus for treatment with flash radiotherapy RA Sharma, SX PFISTER, M Vilalta-colomer, BS Sørensen, PR Poulsen, ... US Patent App. 17/968,392, 2023 | | 2023 |
874 Optimizing a combination radio-immunotherapy regimen in a preclinical model of treatment-resistant, high-risk neuroblastoma L Zebertavage, A Erbe, T Aiken, A Schopf, M Nielsen, S Katz, Z Morris, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | | 2022 |
From weakness comes strength SX Pfister Science (New York, NY) 377 (6604), 442-442, 2022 | | 2022 |
HYDROGEN PEROXIDE PRODUCTION AFTER IRRADIATION WITH PROTON BEAM AT VARIOUS DOSE RATES H Kacem, MC Vozenin, S Psoroulas, D Meer, S Safai, M Togno, AJ Lomax, ... Physica Medica 94, S75, 2022 | | 2022 |
IMPACT OF DOSE RATE DELIVERED WITH ELECTRON, PROTON AND PHOTON BEAMS ON THE DEVELOPMENT OF ZEBRAFISH EMBRYOS J Ollivier, V Grilj, PJ Goncalves, B Petit, A Martinotti, P Barrera, ... Physica Medica 94, S91, 2022 | | 2022 |
EZH2 Inhibition Compromises α4-1BB-Mediated Antitumor Efficacy by Reducing the Survival and Effector Programming of CD8+ T Cells CJ Stairiker, SX Pfister, E Hendrickson, W Yang, T Xie, C Lee, H Zhang, ... Frontiers in Immunology 12, 770080, 2021 | | 2021 |