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Kate Lawrenson
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Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
SE Bojesen, KA Pooley, SE Johnatty, J Beesley, K Michailidou, JP Tyrer, ...
Nature genetics 45 (4), 371-384, 2013
6502013
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
PDP Pharoah, YY Tsai, SJ Ramus, CM Phelan, EL Goode, K Lawrenson, ...
Nature genetics 45 (4), 362-370, 2013
4232013
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
CM Phelan, KB Kuchenbaecker, JP Tyrer, SP Kar, K Lawrenson, ...
Nature genetics 49 (5), 680-691, 2017
4152017
A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24
EL Goode, G Chenevix-Trench, H Song, SJ Ramus, M Notaridou, ...
Nature genetics 42 (10), 874-879, 2010
3972010
A three-dimensional microenvironment alters protein expression and chemosensitivity of epithelial ovarian cancer cells in vitro
JM Lee, P Mhawech-Fauceglia, N Lee, LC Parsanian, YG Lin, SA Gayther, ...
Laboratory investigation 93 (5), 528-542, 2013
3712013
Identification of six new susceptibility loci for invasive epithelial ovarian cancer
KB Kuchenbaecker, SJ Ramus, J Tyrer, A Lee, HC Shen, J Beesley, ...
Nature genetics 47 (2), 164-171, 2015
3102015
Genome-wide meta-analyses of breast, ovarian, and prostate cancer association studies identify multiple new susceptibility loci shared by at least two cancer types
SP Kar, J Beesley, A Amin Al Olama, K Michailidou, J Tyrer, ZS Kote-Jarai, ...
Cancer discovery 6 (9), 1052-1067, 2016
195*2016
Prostate cancer reactivates developmental epigenomic programs during metastatic progression
MM Pomerantz, X Qiu, Y Zhu, DY Takeda, W Pan, SC Baca, A Gusev, ...
Nature genetics 52 (8), 790-799, 2020
1932020
Loss of Scribble causes cell competition in mammalian cells
M Norman, KA Wisniewska, K Lawrenson, P Garcia-Miranda, M Tada, ...
Journal of cell science 125 (1), 59-66, 2012
1872012
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer
H Shen, BL Fridley, H Song, K Lawrenson, JM Cunningham, SJ Ramus, ...
Nature communications 4 (1), 1628, 2013
1822013
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21. 31
J Permuth-Wey, K Lawrenson, HC Shen, A Velkova, JP Tyrer, Z Chen, ...
Nature communications 4 (1), 1627, 2013
1402013
Genome-wide significant risk associations for mucinous ovarian carcinoma
Australian Ovarian Cancer Study Group, H Baker, EV Bandera, Y Bean, ...
Nature genetics 47 (8), 888-897, 2015
1172015
A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets
D Jia, Z Liu, N Deng, TZ Tan, RYJ Huang, B Taylor-Harding, DJ Cheon, ...
Cancer letters 382 (2), 203-214, 2016
1112016
A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer
EJ Richards, J Permuth-Wey, Y Li, YA Chen, D Coppola, BM Reid, HY Lin, ...
Oncotarget 6 (33), 34745, 2015
1102015
CAUSEL: an epigenome-and genome-editing pipeline for establishing function of noncoding GWAS variants
S Spisák, K Lawrenson, Y Fu, I Csabai, RT Cottman, JH Seo, C Haiman, ...
Nature medicine 21 (11), 1357-1363, 2015
1092015
Senescent fibroblasts promote neoplastic transformation of partially transformed ovarian epithelial cells in a three-dimensional model of early stage ovarian cancer
K Lawrenson, B Grun, E Benjamin, IJ Jacobs, D Dafou, SA Gayther
Neoplasia 12 (4), 317-IN3, 2010
1092010
A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants
A Gusev, K Lawrenson, X Lin, PC Lyra Jr, S Kar, KC Vavra, F Segato, ...
Nature genetics 51 (5), 815-823, 2019
1052019
Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer
SC Baca, DY Takeda, JH Seo, J Hwang, SY Ku, R Arafeh, T Arnoff, ...
Nature Communications 12 (1), 1979, 2021
952021
Functional mechanisms underlying pleiotropic risk alleles at the 19p13. 1 breast–ovarian cancer susceptibility locus
K Lawrenson, S Kar, K McCue, K Kuchenbaeker, K Michailidou, J Tyrer, ...
Nature communications 7 (1), 12675, 2016
932016
Stromal expression of fibroblast activation protein alpha (FAP) predicts platinum resistance and shorter recurrence in patients with epithelial ovarian cancer
P Mhawech-Fauceglia, L Yan, M Sharifian, X Ren, S Liu, G Kim, ...
Cancer Microenvironment 8, 23-31, 2015
892015
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