Richard Boucher
Richard Boucher
Professor of Medicine, University of NC at Chapel Hill
Verified email at - Homepage
Cited by
Cited by
Mucus clearance as a primary innate defense mechanism for mammalian airways
MR Knowles, RC Boucher
The Journal of clinical investigation 109 (5), 571-577, 2002
Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients
D Worlitzsch, R Tarran, M Ulrich, U Schwab, A Cekici, KC Meyer, P Birrer, ...
The Journal of clinical investigation 109 (3), 317-325, 2002
SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract
YJ Hou, K Okuda, CE Edwards, DR Martinez, T Asakura, KH Dinnon, ...
Cell 182 (2), 429-446. e14, 2020
Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease
H Matsui, BR Grubb, R Tarran, SH Randell, JT Gatzy, CW Davis, ...
Cell 95 (7), 1005-1015, 1998
CFTR as a cAMP-dependent regulator of sodium channels
MJ Stutts, CM Canessa, JC Olsen, M Hamrick, JA Cohn, BC Rossier, ...
Science 269 (5225), 847-850, 1995
An animal model for cystic fibrosis made by gene targeting
JN Snouwaert, KK Brigman, AM Latour, NN Malouf, RC Boucher, ...
Science 257 (5073), 1083-1088, 1992
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice
M Mall, BR Grubb, JR Harkema, WK O'Neal, RC Boucher
Nature medicine 10 (5), 487-493, 2004
Early death due to defective neonatal lung liquid clearance in αENaC-deficient mice
E Hummler, P Barker, J Gatzy, F Beermann, C Verdumo, A Schmidt, ...
Nature genetics 12 (3), 325-328, 1996
SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo
YJ Hou, S Chiba, P Halfmann, C Ehre, M Kuroda, KH Dinnon III, SR Leist, ...
Science 370 (6523), 1464-1468, 2020
A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia
B Button, LH Cai, C Ehre, M Kesimer, DB Hill, JK Sheehan, RC Boucher, ...
Science 337 (6097), 937-941, 2012
Mucus clearance and lung function in cystic fibrosis with hypertonic saline
SH Donaldson, WD Bennett, KL Zeman, MR Knowles, R Tarran, ...
New England Journal of Medicine 354 (3), 241-250, 2006
New concepts of the pathogenesis of cystic fibrosis lung disease
RC Boucher
European Respiratory Journal 23 (1), 146-158, 2004
Submucosal glands are the predominant site of CFTR expression in the human bronchus
JF Engelhardt, JR Yankaskas, SA Ernst, Y Yang, CR Marino, RC Boucher, ...
Nature genetics 2 (3), 240-248, 1992
Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase.
B Sarkadi, EM Price, RC Boucher, UA Germann, GA Scarborough
Journal of Biological Chemistry 267 (7), 4854-4858, 1992
Muc5b is required for airway defence
MG Roy, A Livraghi-Butrico, AA Fletcher, MM McElwee, SE Evans, ...
Nature 505 (7483), 412-416, 2014
Increased bioelectric potential difference across respiratory epithelia in cystic fibrosis
M Knowles, J Gatzy, R Boucher
New England Journal of Medicine 305 (25), 1489-1495, 1981
Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis
SS Yoon, RF Hennigan, GM Hilliard, UA Ochsner, K Parvatiyar, ...
Developmental cell 3 (4), 593-603, 2002
SARS-CoV-2 infection of the oral cavity and saliva
N Huang, P Pérez, T Kato, Y Mikami, K Okuda, RC Gilmore, CD Conde, ...
Nature medicine 27 (5), 892-903, 2021
A controlled study of adenoviral-vector–mediated gene transfer in the nasal epithelium of patients with cystic fibrosis
MR Knowles, KW Hohneker, Z Zhou, JC Olsen, TL Noah, PC Hu, ...
New England Journal of Medicine 333 (13), 823-831, 1995
Mechanisms of release of nucleotides and integration of their action as P2X-and P2Y-receptor activating molecules
ER Lazarowski, RC Boucher, TK Harden
Molecular pharmacology 64 (4), 785-795, 2003
The system can't perform the operation now. Try again later.
Articles 1–20