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Isin Nergiz Geren
Isin Nergiz Geren
Professor of Molecular Biology and Genetics, Istanbul Medeniyet University
Verified email at medeniyet.edu.tr
Title
Cited by
Cited by
Year
Sequence variation within botulinum neurotoxin serotypes impacts antibody binding and neutralization
TJ Smith, J Lou, IN Geren, CM Forsyth, R Tsai, SL Laporte, WH Tepp, ...
Infection and immunity 73 (9), 5450-5457, 2005
3122005
Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin
C Garcia-Rodriguez, R Levy, JW Arndt, CM Forsyth, A Razai, J Lou, ...
Nature biotechnology 25 (1), 107-116, 2007
2162007
Molecular evolution of antibody affinity for sensitive detection of botulinum neurotoxin type A
A Razai, C Garcia-Rodriguez, J Lou, IN Geren, CM Forsyth, Y Robles, ...
Journal of molecular biology 351 (1), 158-169, 2005
1612005
Fine and domain-level epitope mapping of botulinum neurotoxin type A neutralizing antibodies by yeast surface display
R Levy, CM Forsyth, SL LaPorte, IN Geren, LA Smith, JD Marks
Journal of molecular biology 365 (1), 196-210, 2007
1272007
Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
JD Marks, P Amersdorfer
US Patent 7,563,874, 2009
82*2009
Neutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin
C Garcia-Rodriguez, IN Geren, J Lou, F Conrad, C Forsyth, W Wen, ...
Protein engineering, design & selection 24 (3), 321-331, 2011
672011
Extraction and inhibition of enzymatic activity of botulinum neurotoxins/A1,/A2, and/A3 by a panel of monoclonal anti-BoNT/A antibodies
SR Kalb, J Lou, C Garcia-Rodriguez, IN Geren, TJ Smith, H Moura, ...
Plos one 4 (4), e5355, 2009
652009
Affinity maturation of human botulinum neurotoxin antibodies by light chain shuffling via yeast mating
J Lou, I Geren, C Garcia-Rodriguez, CM Forsyth, W Wen, K Knopp, ...
Protein Engineering, Design & Selection 23 (4), 311-319, 2010
572010
Recombinant anthrax toxin receptor-Fc fusion proteins produced in plants protect rabbits against inhalational anthrax
KL Wycoff, A Belle, D Deppe, L Schaefer, JM Maclean, S Haase, ...
Antimicrobial agents and chemotherapy 55 (1), 132-139, 2011
482011
Molecular architecture of botulinum neurotoxin E revealed by single particle electron microscopy
A Fischer, C Garcia-Rodriguez, I Geren, J Lou, JD Marks, T Nakagawa, ...
Journal of Biological Chemistry 283 (7), 3997-4003, 2008
452008
The use of Endopep-MS to detect multiple subtypes of botulinum neurotoxins A, B, E, and F
SR Kalb, TJ Smith, H Moura, K Hill, J Lou, IN Geren, C Garcia-Rodriguez, ...
International journal of mass spectrometry 278 (2-3), 101-108, 2008
442008
Extraction and inhibition of enzymatic activity of botulinum neurotoxins/B1,/B2,/B3,/B4, and/B5 by a panel of monoclonal anti-BoNT/B antibodies
SR Kalb, WI Santana, IN Geren, C Garcia-Rodriguez, J Lou, TJ Smith, ...
BMC biochemistry 12 (1), 1-11, 2011
262011
Antibodies for botulinum neurotoxins
JD Marks, MCG Rodriguez
US Patent 9,243,057, 2016
232016
A three monoclonal antibody combination potently neutralizes multiple botulinum neurotoxin serotype E subtypes
C Garcia-Rodriguez, A Razai, IN Geren, J Lou, F Conrad, WH Wen, ...
Toxins 10 (3), 105, 2018
222018
Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
JD Marks, I Geren, J Lou
US Patent 7,700,738, 2010
222010
Antibodies That Neutralize Botulinum Neurotoxins
Marks, J D., Lou, Jianlong, Rodriguez, MC Garcia, Geren, I N.
US Patent WO2010/014854 A2, 2010
19*2010
Monoclonal antibodies that inhibit the proteolytic activity of botulinum neurotoxin serotype/B
Y Fan, J Dong, J Lou, W Wen, F Conrad, IN Geren, C Garcia-Rodriguez, ...
Toxins 7 (9), 3405-3423, 2015
152015
Monoclonal antibodies targeting the alpha-exosite of botulinum neurotoxin serotype/A inhibit catalytic activity
Y Fan, IN Geren, J Dong, J Lou, W Wen, F Conrad, TJ Smith, LA Smith, ...
PLoS One 10 (8), e0135306, 2015
142015
Therapeutic Monoclonal Antibodies that Neutralize Botulinum Neurotoxins
JD Marks, P Amersdorfer, I Geren, J Lou, A Razai, MC Garcia
US Patent App. 13/175,628, 2012
122012
Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
JD Marks, MC Garcia
US Patent 9,902,780, 2018
92018
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