Dr. Joseph M Hayes
Dr. Joseph M Hayes
Senior Lecturer in Computational Biology, University of Central Lancashire, Preston, U.K.
uclan.ac.uk üzerinde doğrulanmış e-posta adresine sahip
Alıntı yapanlar
Alıntı yapanlar
Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure− activity relationships, and X-ray crystallographic studies
X Wen, H Sun, J Liu, K Cheng, P Zhang, L Zhang, J Hao, L Zhang, P Ni, ...
Journal of medicinal chemistry 51 (12), 3540-3554, 2008
New inhibitors of glycogen phosphorylase as potential antidiabetic agents
L Somsák, K Czifrák, M Tóth, E Bokor, ED Chrysina, KM Alexacou, ...
Current medicinal chemistry 15 (28), 2933-2983, 2008
Kinetics, in silico docking, molecular dynamics, and MM‐GBSA binding studies on prototype indirubins, KT5720, and staurosporine as phosphorylase kinase ATP …
JM Hayes, VT Skamnaki, G Archontis, C Lamprakis, J Sarrou, N Bischler, ...
Proteins: Structure, Function, and Bioinformatics 79 (3), 703-719, 2011
Glucose-based spiro-isoxazolines: A new family of potent glycogen phosphorylase inhibitors
M Benltifa, JM Hayes, S Vidal, D Gueyrard, PG Goekjian, JP Praly, ...
Bioorganic & medicinal chemistry 17 (20), 7368-7380, 2009
Novel enantioselective receptors for N‐protected glutamate and aspartate
A Ragusa, S Rossi, JM Hayes, M Stein, JD Kilburn
Chemistry–A European Journal 11 (19), 5674-5688, 2005
Mechanism of Formation of Silver N-Heterocyclic Carbenes Using Silver Oxide:  A Theoretical Study
JM Hayes, M Viciano, E Peris, G Ujaque, A Lledós
Organometallics 26 (25), 6170-6183, 2007
Natural products and their derivatives as inhibitors of glycogen phosphorylase: potential treatment for type 2 diabetes
JM Hayes, AL Kantsadi, DD Leonidas
Phytochemistry Reviews 13 (2), 471-498, 2014
MM-GB (PB) SA calculations of protein-ligand binding free energies
JM Hayes, G Archontis
Molecular Dynamics-Studies of Synthetic and Biological Macromolecules, 171-190, 2012
1-(3-Deoxy-3-fluoro-β-D-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies
VG Tsirkone, E Tsoukala, C Lamprakis, S Manta, JM Hayes, VT Skamnaki, ...
Bioorganic & medicinal chemistry 18 (10), 3413-3425, 2010
Theoretical reassessment of Whelk‐O1 as an enantioselective receptor for 1‐(4‐halogeno‐phenyl)‐1‐ethylamine derivatives
A Del Rio, JM Hayes, M Stein, P Piras, C Roussel
Chirality: The Pharmacological, Biological, and Chemical Consequences of …, 2004
The σ‐Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen …
AL Kantsadi, JM Hayes, S Manta, VT Skamnaki, C Kiritsis, AMG Psarra, ...
ChemMedChem 7 (4), 722-732, 2012
Accurate calculations of ligand binding free energies: chiral separation with enantioselective receptors
JM Hayes, M Stein, J Weiser
The Journal of Physical Chemistry A 108 (16), 3572-3580, 2004
Effect of micro and bulk solvation on the mechanism of nucleophilic substitution at sulfur in disulfides
JM Hayes, SM Bachrach
The Journal of Physical Chemistry A 107 (39), 7952-7961, 2003
Computation as a tool for glycogen phosphorylase inhibitor design
J M Hayes, D D Leonidas
Mini Reviews in Medicinal Chemistry 10 (12), 1156-1174, 2010
Antihypertensive Drug Valsartan in Solution and at the AT1 Receptor: Conformational Analysis, Dynamic NMR Spectroscopy, in Silico Docking, and Molecular …
C Potamitis, M Zervou, V Katsiaras, P Zoumpoulakis, S Durdagi, ...
Journal of chemical information and modeling 49 (3), 726-739, 2009
Crystallographic and computational studies on 4‐phenyl‐N‐(β‐D‐glucopyranosyl)‐1H‐1, 2, 3‐triazole‐1‐acetamide, an inhibitor of glycogen phosphorylase: Comparison with α‐D …
KM Alexacou, JM Hayes, C Tiraidis, SE Zographos, DD Leonidas, ...
Proteins: Structure, Function, and Bioinformatics 71 (3), 1307-1323, 2008
Density functional theory gas-and solution-phase study of nucleophilic substitution at di-and trisulfides
SM Bachrach, JM Hayes, T Dao, JL Mynar
Theoretical Chemistry Accounts 107 (5), 266-271, 2002
A force‐field description of short‐range repulsions for high density alkane molecular dynamics simulations
JM Hayes, JC Greer, DA Morton–Blake
Journal of computational chemistry 25 (16), 1953-1966, 2004
Phytogenic polyphenols as glycogen phosphorylase inhibitors: the potential of triterpenes and flavonoids for glycaemic control in type 2 diabetes
G A Stravodimos, B A Chetter, E Kyriakis, A L Kantsadi, ...
Current medicinal chemistry 24 (4), 384-403, 2017
Ketone hydrogenation with iridium complexes with “non N–H” ligands: the key role of the strong base
JM Hayes, E Deydier, G Ujaque, A Lledós, R Malacea-Kabbara, ...
ACS Catalysis 5 (7), 4368-4376, 2015
Sistem, işlemi şu anda gerçekleştiremiyor. Daha sonra yeniden deneyin.
Makaleler 1–20