| Reproducing human and cross-species drug toxicities using a Liver-Chip KJ Jang, MA Otieno, J Ronxhi, HK Lim, L Ewart, KR Kodella, ... Science translational medicine 11 (517), eaax5516, 2019 | 324 | 2019 |
| The conduct of in vitro studies to address time-dependent inhibition of drug-metabolizing enzymes: a perspective of the pharmaceutical research and manufacturers of America SW Grimm, HJ Einolf, SD Hall, K He, HK Lim, KHJ Ling, C Lu, AA Nomeir, ... Drug Metabolism and Disposition 37 (7), 1355-1370, 2009 | 324 | 2009 |
| A method for the simultaneous evaluation of the activities of seven major human drug-metabolizing cytochrome P450s using an in vitro cocktail of probe substrates and fast … EA Dierks, KR Stams, HK Lim, G Cornelius, H Zhang, SE Ball Drug Metabolism and Disposition 29 (1), 23-29, 2001 | 315 | 2001 |
| Recognition of cell‐wall peptide ligands by vancomycin group antibiotics: Studies using ion spray mass spectrometry HK Lim, YL Hsieh, B Ganem, J Henion Journal of Mass Spectrometry 30 (5), 708-714, 1995 | 170 | 1995 |
| In vivo and in vitro metabolism of 3, 4-(methylenedioxy) methamphetamine in the rat: identification of metabolites using an ion trap detector HK Lim, RL Foltz Chemical research in toxicology 1 (6), 370-378, 1988 | 159 | 1988 |
| Metabolite identification by data‐dependent accurate mass spectrometric analysis at resolving power of 60 000 in external calibration mode using an LTQ/Orbitrap HK Lim, J Chen, C Sensenhauser, K Cook, V Subrahmanyam Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2007 | 132 | 2007 |
| Automated screening with confirmation of mechanism-based inactivation of CYP3A4, CYP2C9, CYP2C19, CYP2D6, and CYP1A2 in pooled human liver microsomes HK Lim, N Duczak, L Brougham, M Elliot, K Patel, K Chan Drug metabolism and disposition 33 (8), 1211-1219, 2005 | 115 | 2005 |
| Pharmacological Profile of the 5‐HT2C Receptor Agonist WAY‐163909; Therapeutic Potential in Multiple Indications J Dunlop, KL Marquis, HK Lim, L Leung, J Kao, C Cheesman, ... CNS drug reviews 12 (3‐4), 167-177, 2006 | 104 | 2006 |
| The effect of a high‐fat meal on the oral bioavailability of the immunosuppressant sirolimus (rapamycin) JJ Zimmerman, GM Ferron, HK Lim, V Parker The Journal of Clinical Pharmacology 39 (11), 1155-1161, 1999 | 97 | 1999 |
| A generic method to detect electrophilic intermediates using isotopic pattern triggered data‐dependent high‐resolution accurate mass spectrometry HK Lim, J Chen, K Cook, C Sensenhauser, J Silva, DC Evans Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2008 | 91 | 2008 |
| Fasiglifam (TAK-875): mechanistic investigation and retrospective identification of hazards for drug induced liver injury MA Otieno, J Snoeys, W Lam, A Ghosh, MR Player, A Pocai, R Salter, ... Toxicological sciences 163 (2), 374-384, 2018 | 88 | 2018 |
| Effects of 3, 4-dihydroxymethamphetamine and 2, 4, 5-trihydroxymethamphetamine, two metabolites of 3, 4-methylenedioxymethamphetamine, on central serotonergic and dopaminergic … M Johnson, I Elayan, GR Hanson, RL Foltz, JW Gibb, HK Lim Journal of Pharmacology and Experimental Therapeutics 261 (2), 447-453, 1992 | 81 | 1992 |
| Rapid drug metabolite profiling using fast liquid chromatography, automated multiple-stage mass spectrometry and receptor-binding HK Lim, S Stellingweif, S Sisenwine, KW Chan Journal of chromatography A 831 (2), 227-241, 1999 | 79 | 1999 |
| Quantification of LSD and N-demethyl-LSD in urine by gas chromatography/resonance electron capture ionization mass spectrometry HK Lim, D Andrenyak, P Francom, RL Foltz, RT Jones Analytical chemistry 60 (14), 1420-1425, 1988 | 75 | 1988 |
| Development of enantioselective gas chromatographic quantitation assay for dl-threo-methylphenidate in biological fluids HK Lim, JW Hubbard, KK Midha Journal of Chromatography B: Biomedical Sciences and Applications 378, 109-123, 1986 | 70 | 1986 |
| Metabolism and excretion of canagliflozin in mice, rats, dogs, and humans RNVS Mamidi, F Cuyckens, J Chen, E Scheers, D Kalamaridis, R Lin, ... Drug Metabolism and Disposition 42 (5), 903-916, 2014 | 69 | 2014 |
| Design and Characterization of Optimized Adenosine A2A/A1 Receptor Antagonists for the Treatment of Parkinson's Disease BC Shook, S Rassnick, N Wallace, J Crooke, M Ault, D Chakravarty, ... Journal of medicinal chemistry 55 (3), 1402-1417, 2012 | 67 | 2012 |
| Determination of LSD in urine by capillary column gas chromatography and electron impact mass spectrometry P Francom, D Andrenyak, HK Lim, RR Bridges, RL Foltz, RT Jones Journal of analytical toxicology 12 (1), 1-8, 1988 | 65 | 1988 |
| Identification of a novel route of extraction of sirolimus in human small intestine: roles of metabolism and secretion MF Paine, LY Leung, HK Lim, K Liao, A Oganesian, MY Zhang, ... Journal of Pharmacology and Experimental Therapeutics 301 (1), 174-186, 2002 | 63 | 2002 |
| Identification of metabolites of 3, 4-(methylenedioxy) methamphetamine in human urine HK Lim, RL Foltz Chemical Research in Toxicology 2 (3), 142-143, 1989 | 60 | 1989 |
