Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA. A Jacobo-Molina, J Ding, RG Nanni, AD Clark Jr, X Lu, C Tantillo, ... Proceedings of the National Academy of Sciences 90 (13), 6320-6324, 1993 | 1500 | 1993 |
Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase: implications for mechanisms of drug … C Tantillo, J Ding, A Jacobo-Molina, RG Nanni, PL Boyer, SH Hughes, ... Journal of molecular biology 243 (3), 369-387, 1994 | 700 | 1994 |
Crystal structure of HIV‐1 reverse transcriptase in complex with a polypurine tract RNA: DNA SG Sarafianos, K Das, C Tantillo, AD ClarkJr, J Ding, JM Whitcomb, ... The EMBO journal, 2001 | 534 | 2001 |
Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2 … J Ding, K Das, Y Hsiou, SG Sarafianos, AD Clark Jr, A Jacobo-Molina, ... Journal of molecular biology 284 (4), 1095-1111, 1998 | 421 | 1998 |
Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor α-APA R 95845 at 2.8 Å resolution J Ding, K Das, C Tantillo, W Zhang, AD Clark Jr, S Jessen, X Lu, Y Hsiou, ... Structure 3 (4), 365-379, 1995 | 283 | 1995 |
Insights into DNA polymerization mechanisms from structure and function analysis of HIV-1 reverse transcriptase PH Patel, A Jacobo-Molina, J Ding, C Tantillo, AD Clark Jr, R Raag, ... Biochemistry 34 (16), 5351-5363, 1995 | 245 | 1995 |
Sensitivity of wild-type human immunodeficiency virus type 1 reverse transcriptase to dideoxynucleotides depends on template length; the sensitivity of drug-resistant mutants … PL Boyer, C Tantillo, A Jacobo-Molina, RG Nanni, J Ding, E Arnold, ... Proceedings of the National Academy of Sciences 91 (11), 4882-4886, 1994 | 180 | 1994 |
Mutational analysis of the fingers and palm subdomains of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase PL Boyer, AL Ferris, P Clark, J Whitmer, P Frank, C Tantillo, E Arnold, ... Journal of molecular biology 243 (3), 472-483, 1994 | 109 | 1994 |
An expanded model of replicating human immunodeficiency virus reverse transcriptase BM Woehrl, C Tantillo, E Arnold, SFJ Le Grice Biochemistry 34 (16), 5343-5350, 1995 | 94 | 1995 |
Buried surface analysis of HIV‐1 reverse transcriptase p66/p51 heterodimer and its interaction with dsDNA template/primer J Ding, A Jacobo‐Molina, C Tantillo, X Lu, RG Nanni, E Arnold Journal of molecular recognition 7 (2), 157-161, 1994 | 27 | 1994 |
Structure of HIV-1 reverse transcriptase/dsDNA/Fab complex: protein-DNA interactions and structure of the polymerase active site J Ding, A Jacobo-Molina, RG Nanni, X Lu, C Tantillo, AD Clark Jr, ... Acta Crystallographica Section A 49, c154-c155, 1993 | 1 | 1993 |
MOLECULAR MODELING STUDIES OF HIV-1 REVERSE-TRANSCRIPTASE NONNUCLEOSIDE INHIBITORS MBK KOEPKE, CA ROUZER, LA TANEYHILL, NA SMITH, SH HUGHES, ... ACS National Meeting Book of Abstracts 210, 93-MEDI, 1995 | | 1995 |
MECHANISMS OF RESISTANCE OF HIV-1 RT TO NUCLEOSIDE AND NONNUCLEOSIDE INHIBITORS PL BOYER, C TANTILLO, JP DING, AL FERRIS, P CLARK, E ARNOLD, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 209, 150-MEDI, 1995 | | 1995 |
Mechanisms of resistance of HIV-1 reverse transcriptase to nucleoside and non-nucleoside inhibitors PL Boyer, C Tantillo, J Ding, AL Ferris, P Clark, E Arnold, SH Hughes JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY 10, 6-6, 1995 | | 1995 |
The role of nucleic acid in the resistance of HIV-1 reverse transcriptase to nucleoside and non-nucleoside inhibitors E Arnold, K Das, JP Ding, Y Hsiou, C Tantillo, BM Roy, P Yadav, ... Journal of acquired immune deficiency syndromes and human retrovirology …, 1995 | | 1995 |
3-DIMENSIONAL STRUCTURES OF HIV-1 REVERSE-TRANSCRIPTASE COMPLEXED WITH A DSDNA TEMPLATE-PRIMER AND A NONNUCLEOSIDE INHIBITOR J DING, C TANTILLO, S JESSEN, A JACOBOMOLINA, X LU, RG NANNI, ... BIOPHYSICAL JOURNAL 66 (2), A358-A358, 1994 | | 1994 |
Mutational Analysis of the Fingers and Palm Subdomains of Human Immunodeficiency Virus Type-1 (HIV-1) Reverse PL Boyer, AL Ferris, P Clark, J Whitmer, P Frank, C Tantillo, E Arnold, ... | | |