|De novo mutations revealed by whole-exome sequencing are strongly associated with autism|
SJ Sanders, MT Murtha, AR Gupta, JD Murdoch, MJ Raubeson, ...
Nature 485 (7397), 237-241, 2012
|Synaptic, transcriptional and chromatin genes disrupted in autism|
S De Rubeis, X He, AP Goldberg, CS Poultney, K Samocha, AE Cicek, ...
Nature 515 (7526), 209-215, 2014
|The contribution of de novo coding mutations to autism spectrum disorder|
I Iossifov, BJ O’roak, SJ Sanders, M Ronemus, N Krumm, D Levy, ...
Nature 515 (7526), 216-221, 2014
|Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs|
SH Lee, S Ripke, BM Neale, SV Faraone, SM Purcell, RH Perlis, ...
Nature genetics 45 (9), 984-995, 2013
|Insights into autism spectrum disorder genomic architecture and biology from 71 risk loci|
SJ Sanders, X He, AJ Willsey, AG Ercan-Sencicek, KE Samocha, ...
Neuron 87 (6), 1215-1233, 2015
|Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism|
AJ Willsey, SJ Sanders, M Li, S Dong, AT Tebbenkamp, RA Muhle, ...
Cell 155 (5), 997-1007, 2013
|Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism|
FK Satterstrom, JA Kosmicki, J Wang, MS Breen, S De Rubeis, JY An, ...
Cell 180 (3), 568-584. e23, 2020
|Common genetic variants, acting additively, are a major source of risk for autism|
L Klei, SJ Sanders, MT Murtha, V Hus, JK Lowe, AJ Willsey, ...
Molecular autism 3 (1), 1-13, 2012
|Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders|
PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ...
Cell 179 (7), 1469-1482. e11, 2019
|Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders|
DJ Weiner, EM Wigdor, S Ripke, RK Walters, JA Kosmicki, J Grove, ...
Nature genetics 49 (7), 978-985, 2017
|Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways|
T Network, ...
Nature neuroscience 18 (2), 199, 2015
|The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment|
J Cotney, RA Muhle, SJ Sanders, L Liu, AJ Willsey, W Niu, W Liu, L Klei, ...
Nature communications 6 (1), 1-11, 2015
|The psychencode project|
S Akbarian, C Liu, JA Knowles, FM Vaccarino, PJ Farnham, GE Crawford, ...
Nature neuroscience 18 (12), 1707-1712, 2015
|Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence data|
JT Glessner, AG Bick, K Ito, JG Homsy, L Rodriguez-Murillo, M Fromer, ...
Circulation research 115 (10), 884-896, 2014
|Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation|
CT Watson, KM Steinberg, J Huddleston, RL Warren, M Malig, J Schein, ...
The American Journal of Human Genetics 92 (4), 530-546, 2013
|Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24. 32 and a significant overlap with schizophrenia|
Molecular autism 8, 1-17, 2017
|Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder|
R Maier, G Moser, GB Chen, S Ripke, D Absher, I Agartz, H Akil, F Amin, ...
The American Journal of Human Genetics 96 (2), 283-294, 2015
|An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder|
DM Werling, H Brand, JY An, MR Stone, L Zhu, JT Glessner, RL Collins, ...
Nature genetics 50 (5), 727-736, 2018
|Using large clinical data sets to infer pathogenicity for rare copy number variants in autism cohorts|
D Moreno-De-Luca, SJ Sanders, AJ Willsey, JG Mulle, JK Lowe, ...
Molecular psychiatry 18 (10), 1090-1095, 2013
|Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder|
JY An, K Lin, L Zhu, DM Werling, S Dong, H Brand, HZ Wang, X Zhao, ...
Science 362 (6420), eaat6576, 2018