|Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors|
SN Baytas, N Inceler, A Yılmaz, A Olgac, S Menevse, E Banoglu, E Hamel, ...
Bioorganic & medicinal chemistry 22 (12), 3096-3104, 2014
|4, 5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP)|
E Banoglu, E Çelikoğlu, S Völker, A Olgaç, J Gerstmeier, U Garscha, ...
European Journal of Medicinal Chemistry 113, 1-10, 2016
|The potential role of in silico approaches to identify novel bioactive molecules from natural resources|
A Olğaç, IE Orhan, E Banoglu
Future Medicinal Chemistry 9 (14), 1665-1686, 2017
|Ortho versus Meta Chlorophenyl-2,3-BenzodiazepineAnalogues; Synthesis, Molecular Modeling, and Biological Activity as AMPAR Antagonists|
M Qneibi, N Jaradat, M Hawash, A Olgac, N Emwas
ACS OMEGA, 2020
|Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors|
M Boccellino, M Donniacuo, F Bruno, B Rinaldi, L Quagliuolo, A Marika, ...
European Journal of Medicinal Chemistry, 2019
|Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7|
ZT Gür, B Çalışkan, UI Garscha, A Olgaç, US Schubert, J Gerstmeier, ...
European Journal of Medicinal Chemistry 150, 876-899, 2018
|Structural insight into the optimization of ethyl 5-hydroxybenzo [g] indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress …|
F Bruno, S Errico, S Pace, MB Nawrozkij, AS Mkrtchyan, F Guida, ...
European Journal of Medicinal Chemistry 155, 946-960, 2018
|Cloud-Based High Throughput Virtual Screening in Novel Drug Discovery|
A Olğaç, Abdurrahman, Türe, S Olğaç, S Möller
High-Performance Modelling and Simulation for Big Data Applications 11400 …, 2019
|Design and Synthesis of Novel Substituted Indole-acrylamide Derivatives and Evaluation of Their Anti-Cancer Activity as Potential Tubulin-Targeting Agents|
M Hawash, D Cansen Kahraman, A Olğaç, S Güntekin Ergün, E Hamel, ...
Journal of Molecular Structure, 132345, 2022
|Synthesis and biological evaluation of C (5)-substituted derivatives of leukotriene biosynthesis inhibitor BRP-7|
S Levent, J Gerstmeier, A Olgaç, F Nikels, U Garscha, A Carotti, ...
European Journal of Medicinal Chemistry 122, 510-519, 2016
|Discovery of novel 5-lipoxygenase-activating protein (FLAP) inhibitors by exploiting a multistep virtual screening protocol|
A Olgac, A Carotti, C Kretzer, S Zergiebel, A Seeling, U Garscha, O Werz, ...
Journal of Chemical Information and Modeling 60 (3), 1737-1748, 2020
|Novel potent benzimidazole-based microsomal prostaglandin E2 Synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase|
AG Ergül, T Gür Maz, C Kretzer, A Olğaç, PM Jordan, B Çalışkan, O Werz, ...
European Journal of Medicinal Chemistry, 2022
|Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacy|
T Gürses, A Olğaç, U Garscha, T Gür Maz, NB Bal, O Uludağ, B Çalışkan, ...
Bioorganic Chemistry, 2021
|Fragment-based drug design of nature-inspired compounds|
A Najjar, A Olğaç, F Ntie-Kang, W Sippl
Physical Sciences Reviews, 2019
|Novel Indole-Pyrazole Hybrids as Potential Tubulin-Targeting Agents; Synthesis, antiproliferative evaluation, and molecular modeling studies|
M Hawash, S Güntekin Ergün, D Cansen Kahraman, A Olğaç, E Hamel, ...
Journal of Molecular Structure, 2023
|Identification of Novel Antiplatelet Agents by Targeting Glycoprotein VI: A Combined Virtual Screening Study|
S Olgac, A Olgac, I Yenicesu, Y Ozkan
Bioorganic Chemistry, 2022
|Quinazoline-4(3H)-one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition|
S Turanli, AG Ergül, PM Jordan, A Olğaç, B Çalışkan, O Werz, E Banoglu
ACS Omega, 2022
|Discovery and optimization of piperazine urea derivatives as soluble epoxide hydrolase (sEH) inhibitors|
İ Çapan, PM Jordan, A Olğaç, B Çalışkan, C Kretzer, O Werz, E Banoglu
|Mitochondrial Haplogroup Distribution in Elite Turkish Athletes|
M Kurtuluş, M Günay, Ç Çelenk, A Olğaç, T Kesici
Beden Eğitimi ve Spor Bilimleri Dergisi 14 (3), 504-512, 2020
|Evias Web Services Cloud Based Drug Discovery Platform|
A OLĞAÇ, G BUDAK, S OLĞAÇ, R NUTI, A CAROTTI, E BANOĞLU