Abdurrahman OLĞAÇ
Abdurrahman OLĞAÇ
Gazi University Faculty of Pharmacy
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Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors
SN Baytas, N Inceler, A Yılmaz, A Olgac, S Menevse, E Banoglu, E Hamel, ...
Bioorganic & medicinal chemistry 22 (12), 3096-3104, 2014
4, 5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP)
E Banoglu, E Çelikoğlu, S Völker, A Olgaç, J Gerstmeier, U Garscha, ...
European Journal of Medicinal Chemistry 113, 1-10, 2016
The potential role of in silico approaches to identify novel bioactive molecules from natural resources
A Olğaç, IE Orhan, E Banoglu
Future Medicinal Chemistry 9 (14), 1665-1686, 2017
Ortho versus Meta Chlorophenyl-2,3-BenzodiazepineAnalogues; Synthesis, Molecular Modeling, and Biological Activity as AMPAR Antagonists
M Qneibi, N Jaradat, M Hawash, A Olgac, N Emwas
Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors
M Boccellino, M Donniacuo, F Bruno, B Rinaldi, L Quagliuolo, A Marika, ...
European Journal of Medicinal Chemistry, 2019
Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7
ZT Gür, B Çalışkan, UI Garscha, A Olgaç, US Schubert, J Gerstmeier, ...
European Journal of Medicinal Chemistry 150, 876-899, 2018
Cloud-Based High Throughput Virtual Screening in Novel Drug Discovery
A Olğaç, Abdurrahman, Türe, S Olğaç, S Möller
High-Performance Modelling and Simulation for Big Data Applications 11400 …, 2019
Structural insight into the optimization of ethyl 5-hydroxybenzo [g] indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress …
F Bruno, S Errico, S Pace, MB Nawrozkij, AS Mkrtchyan, F Guida, ...
European Journal of Medicinal Chemistry 155, 946-960, 2018
Design and Synthesis of Novel Substituted Indole-acrylamide Derivatives and Evaluation of Their Anti-Cancer Activity as Potential Tubulin-Targeting Agents
M Hawash, D Cansen Kahraman, A Olğaç, S Güntekin Ergün, E Hamel, ...
Journal of Molecular Structure, 132345, 2022
Synthesis and biological evaluation of C (5)-substituted derivatives of leukotriene biosynthesis inhibitor BRP-7
S Levent, J Gerstmeier, A Olgaç, F Nikels, U Garscha, A Carotti, ...
European Journal of Medicinal Chemistry 122, 510-519, 2016
Novel Indole-Pyrazole Hybrids as Potential Tubulin-Targeting Agents; Synthesis, antiproliferative evaluation, and molecular modeling studies
M Hawash, S Güntekin Ergün, D Cansen Kahraman, A Olğaç, E Hamel, ...
Journal of Molecular Structure, 2023
Discovery of novel 5-lipoxygenase-activating protein (FLAP) inhibitors by exploiting a multistep virtual screening protocol
A Olgac, A Carotti, C Kretzer, S Zergiebel, A Seeling, U Garscha, O Werz, ...
Journal of Chemical Information and Modeling 60 (3), 1737-1748, 2020
Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacy
T Gürses, A Olğaç, U Garscha, T Gür Maz, NB Bal, O Uludağ, B Çalışkan, ...
Bioorganic Chemistry, 2021
Fragment-based drug design of nature-inspired compounds
A Najjar, A Olğaç, F Ntie-Kang, W Sippl
Physical Sciences Reviews, 2019
Novel potent benzimidazole-based microsomal prostaglandin E2 Synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase
AG Ergül, T Gür Maz, C Kretzer, A Olğaç, PM Jordan, B Çalışkan, O Werz, ...
European Journal of Medicinal Chemistry, 2022
Identification of Novel Antiplatelet Agents by Targeting Glycoprotein VI: A Combined Virtual Screening Study
S Olgac, A Olgac, I Yenicesu, Y Ozkan
Bioorganic Chemistry, 2022
Quinazoline-4(3H)-one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition
S Turanli, AG Ergül, PM Jordan, A Olğaç, B Çalışkan, O Werz, E Banoglu
ACS Omega, 2022
Discovery and optimization of piperazine urea derivatives as soluble epoxide hydrolase (sEH) inhibitors
İ Çapan, PM Jordan, A Olğaç, B Çalışkan, C Kretzer, O Werz, E Banoglu
ChemMedChem, 2022
Novel potent benzimidazole-based microsomal prostaglandin E-2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C-4 synthase
A Ergul, Z GÜR MAZ, C Kretzer, A OLĞAÇ, P Jordan, B ÇALIŞKAN, ...
Mitochondrial Haplogroup Distribution in Elite Turkish Athletes
M Kurtuluş, M Günay, Ç Çelenk, A Olğaç, T Kesici
Beden Eğitimi ve Spor Bilimleri Dergisi 14 (3), 504-512, 2020
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