|Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors|
SN Baytas, N Inceler, A Yılmaz, A Olgac, S Menevse, E Banoglu, E Hamel, ...
Bioorganic & medicinal chemistry 22 (12), 3096-3104, 2014
|4, 5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP)|
E Banoglu, E Çelikoğlu, S Völker, A Olgaç, J Gerstmeier, U Garscha, ...
European journal of medicinal chemistry 113, 1-10, 2016
|The potential role of in silico approaches to identify novel bioactive molecules from natural resources|
A Olğaç, IE Orhan, E Banoglu
Future medicinal chemistry 9 (14), 1665-1686, 2017
|Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors|
M Boccellino, M Donniacuo, F Bruno, B Rinaldi, L Quagliuolo, A Marika, ...
European Journal of Medicinal Chemistry, 2019
|Structural insight into the optimization of ethyl 5-hydroxybenzo [g] indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress …|
F Bruno, S Errico, S Pace, MB Nawrozkij, AS Mkrtchyan, F Guida, ...
European journal of medicinal chemistry 155, 946-960, 2018
|Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7|
ZT Gür, B Çalışkan, UI Garscha, A Olgaç, US Schubert, J Gerstmeier, ...
European journal of medicinal chemistry 150, 876-899, 2018
|Ortho versus Meta Chlorophenyl-2,3-BenzodiazepineAnalogues; Synthesis, Molecular Modeling, and Biological Activity as AMPAR Antagonists|
M Qneibi, N Jaradat, M Hawash, A Olgac, N Emwas
ACS OMEGA, 2020
|Cloud-Based High Throughput Virtual Screening in Novel Drug Discovery|
A Olğaç, Abdurrahman, Türe, S Olğaç, S Möller
High-Performance Modelling and Simulation for Big Data Applications 11400 …, 2019
|Synthesis and biological evaluation of C (5)-substituted derivatives of leukotriene biosynthesis inhibitor BRP-7|
S Levent, J Gerstmeier, A Olgaç, F Nikels, U Garscha, A Carotti, ...
European journal of medicinal chemistry 122, 510-519, 2016
|Discovery of novel 5-lipoxygenase-activating protein (FLAP) inhibitors by exploiting a multistep virtual screening protocol|
A Olgac, A Carotti, C Kretzer, S Zergiebel, A Seeling, U Garscha, O Werz, ...
Journal of chemical information and modeling 60 (3), 1737-1748, 2020
|Fragment-based drug design of nature-inspired compounds|
A Najjar, A Olğaç, F Ntie-Kang, W Sippl
Physical Sciences Reviews, 2019
|Evias Web Services Cloud Based Drug Discovery Platform|
A OLĞAÇ, G BUDAK, S OLĞAÇ, R NUTI, A CAROTTI, E BANOĞLU
|Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacy|
T Gürses, A Olğaç, U Garscha, T Gür Maz, NB Bal, O Uludağ, B Çalışkan, ...
Bioorganic Chemistry, 2021
|Mitochondrial Haplogroup Distribution in Elite Turkish Athletes|
M Kurtuluş, M Günay, Ç Çelenk, A Olğaç, T Kesici
Beden Eğitimi ve Spor Bilimleri Dergisi 14 (3), 504-512, 2020
|The 12th AFMC International Medicinal Chemistry Symposium (AIMECS 2019) in Istanbul, Turkey|
A Olğaç, İ Yalçın, E Akı-Yalçın
ChemMedChem 15 (1), 162-167, 2020
|In Vitro Antiplatelet Studies on Virtually Discovered GPVI Drug Candidates|
S OLĞAÇ, A Olgaç, Y ÖZKAN