Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors SN Baytas, N Inceler, A Yılmaz, A Olgac, S Menevse, E Banoglu, E Hamel, ... Bioorganic & medicinal chemistry 22 (12), 3096-3104, 2014 | 66 | 2014 |
4, 5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP) E Banoglu, E Çelikoğlu, S Völker, A Olgaç, J Gerstmeier, U Garscha, ... European Journal of Medicinal Chemistry 113, 1-10, 2016 | 58 | 2016 |
Ortho versus Meta Chlorophenyl-2,3-BenzodiazepineAnalogues; Synthesis, Molecular Modeling, and Biological Activity as AMPAR Antagonists M Qneibi, N Jaradat, M Hawash, A Olgac, N Emwas ACS OMEGA, 2020 | 37 | 2020 |
The potential role of in silico approaches to identify novel bioactive molecules from natural resources A Olğaç, IE Orhan, E Banoglu Future Medicinal Chemistry 9 (14), 1665-1686, 2017 | 35 | 2017 |
Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors M Boccellino, M Donniacuo, F Bruno, B Rinaldi, L Quagliuolo, A Marika, ... European Journal of Medicinal Chemistry, 2019 | 32 | 2019 |
Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7 ZT Gür, B Çalışkan, UI Garscha, A Olgaç, US Schubert, J Gerstmeier, ... European Journal of Medicinal Chemistry 150, 876-899, 2018 | 30 | 2018 |
Design and Synthesis of Novel Substituted Indole-acrylamide Derivatives and Evaluation of Their Anti-Cancer Activity as Potential Tubulin-Targeting Agents M Hawash, D Cansen Kahraman, A Olğaç, S Güntekin Ergün, E Hamel, ... Journal of Molecular Structure, 132345, 2022 | 24 | 2022 |
Cloud-Based High Throughput Virtual Screening in Novel Drug Discovery A Olğaç, Abdurrahman, Türe, S Olğaç, S Möller High-Performance Modelling and Simulation for Big Data Applications 11400 …, 2019 | 23* | 2019 |
Structural insight into the optimization of ethyl 5-hydroxybenzo [g] indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress … F Bruno, S Errico, S Pace, MB Nawrozkij, AS Mkrtchyan, F Guida, ... European Journal of Medicinal Chemistry 155, 946-960, 2018 | 21 | 2018 |
Novel Indole-Pyrazole Hybrids as Potential Tubulin-Targeting Agents; Synthesis, antiproliferative evaluation, and molecular modeling studies M Hawash, S Güntekin Ergün, D Cansen Kahraman, A Olğaç, E Hamel, ... Journal of Molecular Structure, 2023 | 20 | 2023 |
Novel potent benzimidazole-based microsomal prostaglandin E2 Synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase AG Ergül, T Gür Maz, C Kretzer, A Olğaç, PM Jordan, B Çalışkan, O Werz, ... European Journal of Medicinal Chemistry, 2022 | 13 | 2022 |
Synthesis and biological evaluation of C (5)-substituted derivatives of leukotriene biosynthesis inhibitor BRP-7 S Levent, J Gerstmeier, A Olgaç, F Nikels, U Garscha, A Carotti, ... European Journal of Medicinal Chemistry 122, 510-519, 2016 | 11 | 2016 |
Discovery of novel 5-lipoxygenase-activating protein (FLAP) inhibitors by exploiting a multistep virtual screening protocol A Olgac, A Carotti, C Kretzer, S Zergiebel, A Seeling, U Garscha, O Werz, ... Journal of Chemical Information and Modeling 60 (3), 1737-1748, 2020 | 9 | 2020 |
Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacy T Gürses, A Olğaç, U Garscha, T Gür Maz, NB Bal, O Uludağ, B Çalışkan, ... Bioorganic Chemistry, 2021 | 8 | 2021 |
Fragment-based drug design of nature-inspired compounds A Najjar, A Olğaç, F Ntie-Kang, W Sippl Physical Sciences Reviews, 2019 | 7 | 2019 |
Discovery and optimization of piperazine urea derivatives as soluble epoxide hydrolase (sEH) inhibitors İ Çapan, PM Jordan, A Olğaç, B Çalışkan, C Kretzer, O Werz, E Banoglu ChemMedChem, 2022 | 6 | 2022 |
Identification of Novel Antiplatelet Agents by Targeting Glycoprotein VI: A Combined Virtual Screening Study S Olgac, A Olgac, I Yenicesu, Y Ozkan Bioorganic Chemistry, 2022 | 4 | 2022 |
Quinazoline-4(3H)-one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition S Turanli, AG Ergül, PM Jordan, A Olğaç, B Çalışkan, O Werz, E Banoglu ACS Omega, 2022 | 3 | 2022 |
Mitochondrial Haplogroup Distribution in Elite Turkish Athletes M Kurtuluş, M Günay, Ç Çelenk, A Olğaç, T Kesici Beden Eğitimi ve Spor Bilimleri Dergisi 14 (3), 504-512, 2020 | 2 | 2020 |
Evias Web Services Cloud Based Drug Discovery Platform A OLĞAÇ, G BUDAK, S OLĞAÇ, R NUTI, A CAROTTI, E BANOĞLU | 2 | 2016 |