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Aytekin Köse
Aytekin Köse
Verified email at aksaray.edu.tr - Homepage
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Year
Synthesis and anticancer activity evaluation of new isoindole analogues
A Köse, Y Bal, NH Kishalı, G Şanlı-Mohamed, Y Kara
Medicinal Chemistry Research 26, 779-786, 2017
242017
Synthesis and biological evaluation of new chloro/acetoxy substituted isoindole analogues as new tyrosine kinase inhibitors
A Köse, M Kaya, NH Kishalı, A Akdemir, E Şahin, Y Kara, ...
Bioorganic Chemistry 94, 103421, 2020
142020
Synthesis and anticancer activity of novel derivatives of α, β‐unsaturated ketones based on oleanolic acid: in vitro and in silico studies against prostate cancer cells
H Şenol, M Ghaffari-Moghaddam, Ş Bulut, F Akbaş, A Köse, G Topçu
72023
Reaction of (S)-homoserine lactone with Grignard reagents: synthesis of amino-keto-alcohols and β-amino acid derivatives
Ö Gündoğdu, P Turhan, A Köse, R Altundaş, Y Kara
Tetrahedron: Asymmetry 28 (9), 1163-1168, 2017
52017
Enantiospecific Synthesis of (R)‐3‐Amino‐4‐(2,4,5‐trifluorophenyl)butanoic Acid Using (S)‐Serine as a Chiral Pool
A Köse, Ö Gündoğdu, D Aktaş, M Fıstıkçı, R Altundaş, H Secen, Y Kara
Helvetica Chimica Acta 98 (2), 260-266, 2015
42015
Nucleophilic Reactivity of Ethers Against Terminal Epoxides in the Presence of BF3: A Mechanistic Study
A Kose, R Altundas, H Seçen, Y Kara
Helvetica Chimica Acta 96 (7), 1325-1330, 2013
32013
An anomalous addition of chlorosulfonyl isocyanate to a carbonyl group: the synthesis of ((3aS, 7aR, E)-2-ethyl-3-oxo-2, 3, 3a, 4, 7, 7a-hexahydro-1H-isoindol-1-ylidene …
A Köse, A Ünal, E Şahin, U Bozkaya, Y Kara
Beilstein Journal of Organic Chemistry 15 (1), 931-936, 2019
22019
Unique reaction of cyclicimides containing double bond with chlorosulfonyl isocyanate and theoretical computations: Solvent-free reactions
A Köse, E Soydaş, Y Kara
Journal of Molecular Structure 1274, 134428, 2023
12023
Identification of hCA I, hCA II, AChE and BChE Inhibitory Properties of Some Norcantharimide Derivatives; Molecular Docking, SAR and in silico ADME Studies
L Polat Köse, A Köse
ChemistrySelect 9 (16), e202400684, 2024
2024
Investigation of cytotoxic properties of some isoindole-related compounds bearing silyl and azide groups with in vitro and in silico studies
A Tan, A Köse, D Mete, G Şanlı-Mohamed, NH Kishalı, Y Kara
Phosphorus, Sulfur, and Silicon and the Related Elements 198 (11), 933-942, 2023
2023
Investigation Into The Molecular Stability, Synthesis Mechanism, and Formation of Some Norcantharimide Derivatives Using AcCl or Ac2O: A Mechanism-Based Study
A Köse
Afyon Kocatepe Üniversitesi Fen Ve Mühendislik Bilimleri Dergisi 23 (3), 618-627, 2023
2023
Evaluation of in vivo biological activity profiles of isoindole-1, 3-dione derivatives: Cytotoxicity, toxicology, and histopathology studies
A Köse, M Kaya, C Tomruk, Y Uyanıkgil, N Kishalı, Y Kara, ...
Acs Omega 8 (13), 12512-12521, 2023
2023
4-((3-(Triflorometil) piridin-2-il) oksi) benzohidrazit Birimi İçeren Yeni Hidrazon Türevlerinin Sentezi
A Köse
Journal of the Institute of Science and Technology 11 (4), 2870-2879, 2021
2021
A simple route for the synthesis of novel norcantharimide derivatives via acidolysis with hydrochloric acid(gas)
A Köse
Journal of Heterocyclic Chemistry 58 (5), 1171-1178, 2021
2021
Unusual Reaction of (3aR, 7aS)-2-ethyl-3a, 4, 7, 7a-tetrahydro-1H-isoindole-1, 3 (2H)-Dione and Chlorosulfonylisocyanate (CSI)
A KÖSE, U BOZKAYA, E ŞAHİN, Y KARA
BOOK OF ABSTRACTS, 512, 2017
2017
İsoindol-1, 3-dion Türevlerinin Sentezi ve Tirozin Kinaz Enzimi Üzerine Aktivitelerinin İncelenmesi
A KÖSE, M KAYA, N KİSHALI, G ŞANLI-MOHAMED, Y KARA
EFFECTS OF NOVEL SYNTHESIZED PYRROLE DERIVATIVES ON HeLa CELLS AS POTENTIAL TYROSINE KINASE INHIBITORS
M Kaya, A Kose, Y Kara, G Sanli-Mohamed
Norkantarimid Türevlerinin Sentezi ve Biyolojik Aktivitelerinin İncelenmesi
A KÖSE, N Kishalıa, G Şanlı-Mohamedb, Y Karaa
Yeni Bir Yöntemle B-Etoksialkollerin Sentezi
M Fıstıkçı, A Köse, Ö Gündoğdu, Y Kara
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Articles 1–19