Structural insight into the unique properties of adeno-associated virus serotype 9 MA DiMattia, HJ Nam, K Van Vliet, M Mitchell, A Bennett, BL Gurda, ... Journal of virology 86 (12), 6947-6958, 2012 | 237 | 2012 |
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice CL Bell, LH Vandenberghe, P Bell, MP Limberis, GP Gao, K Van Vliet, ... The Journal of clinical investigation 121 (6), 2427-2435, 2011 | 234 | 2011 |
Targeting photoreceptors via intravitreal delivery using novel, capsid-mutated AAV vectors CN Kay, RC Ryals, GV Aslanidi, SH Min, Q Ruan, J Sun, FM Dyka, ... PloS one 8 (4), e62097, 2013 | 199 | 2013 |
Identification of the galactose binding domain of the adeno-associated virus serotype 9 capsid CL Bell, BL Gurda, K Van Vliet, M Agbandje-McKenna, JM Wilson Journal of virology 86 (13), 7326-7333, 2012 | 153 | 2012 |
The role of the adeno-associated virus capsid in gene transfer KM Van Vliet, V Blouin, N Brument, M Agbandje-McKenna, RO Snyder Drug Delivery Systems, 51-91, 2008 | 144 | 2008 |
Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold? GV Aslanidi, AE Rivers, L Ortiz, L Song, C Ling, L Govindasamy, ... PloS one 8 (3), e59142, 2013 | 135 | 2013 |
Capsid-modified rAAV vector compositions and methods therefor A Srivastava, GV Aslanidi, S Zolotukhin, M Agbandje-McKenna, ... US Patent 10,011,640, 2018 | 104* | 2018 |
A simplified purification protocol for recombinant adeno-associated virus vectors M Potter, B Lins, M Mietzsch, R Heilbronn, K Van Vliet, P Chipman, ... Molecular Therapy-Methods & Clinical Development 1, 2014 | 91 | 2014 |
Poxvirus proteomics and virus-host protein interactions K Van Vliet, MR Mohamed, L Zhang, NY Villa, SJ Werden, J Liu, ... Microbiology and Molecular Biology Reviews 73 (4), 730-749, 2009 | 86 | 2009 |
Gene transfer properties and structural modeling of human stem cell-derived AAV LJ Smith, T Ul-Hasan, SK Carvaines, K Van Vliet, E Yang, KK Wong, ... Molecular Therapy 22 (9), 1625-1634, 2014 | 83 | 2014 |
Impact of heparan sulfate binding on transduction of retina by recombinant adeno-associated virus vectors SL Boye, A Bennett, ML Scalabrino, KT McCullough, K Van Vliet, ... Journal of virology 90 (8), 4215-4231, 2016 | 80 | 2016 |
Structure of neurotropic adeno-associated virus AAVrh. 8 S Halder, K Van Vliet, JK Smith, TTP Duong, R McKenna, JM Wilson, ... Journal of structural biology 192 (1), 21-36, 2015 | 78 | 2015 |
Site-Directed Mutagenesis of Surface-Exposed Lysine Residues Leads to Improved Transduction by AAV2, But Not AAV8, Vectors in Murine Hepatocytes In Vivo B Li, W Ma, C Ling, K Van Vliet, LY Huang, M Agbandje-McKenna, ... Human gene therapy methods 26 (6), 211-220, 2015 | 59 | 2015 |
AAV vectors with high transduction efficiency and uses thereof for gene therapy A Srivastava, GV Aslanidi, KM Van Vliet, M Agbandje-McKenna US Patent 9,725,485, 2017 | 58 | 2017 |
Tunable protease-activatable virus nanonodes J Judd, ML Ho, A Tiwari, EJ Gomez, C Dempsey, K Van Vliet, OA Igoshin, ... ACS nano 8 (5), 4740-4746, 2014 | 58 | 2014 |
A rationally engineered capsid variant of AAV9 for systemic CNS-directed and peripheral tissue-detargeted gene delivery in neonates D Wang, S Li, DJ Gessler, J Xie, L Zhong, J Li, K Tran, K Van Vliet, L Ren, ... Molecular Therapy Methods & Clinical Development 9, 234-246, 2018 | 56 | 2018 |
High-transduction-efficiency raav vectors, compositions, and methods of use A Srivastava, GV Aslanidi, KM Van Vliet, M Agbandje-Mckenna US Patent 9,611,302, 2017 | 44 | 2017 |
Capsid-modified, raav3 vector compositions and uses in gene therapy of human liver cancer A Srivastava, L Zhong, S Zolotukhin, GV Aslanidi, M Agbandje-McKenna, ... US Patent App. 14/891,241, 2016 | 41 | 2016 |
Adeno-associated virus (AAV) capsid stability and liposome remodeling during endo/lysosomal pH trafficking B Lins-Austin, S Patel, M Mietzsch, D Brooke, A Bennett, ... Viruses 12 (6), 668, 2020 | 38 | 2020 |
The structure of AAVrh32. 33, a novel gene delivery vector K Mikals, HJ Nam, K Van Vliet, LH Vandenberghe, LE Mays, R McKenna, ... Journal of structural biology 186 (2), 308-317, 2014 | 36 | 2014 |