Bart Vanhaesebroeck
Bart Vanhaesebroeck
UCL Cancer Institute, University College London, London UK
ucl.ac.uk üzerinde doğrulanmış e-posta adresine sahip - Ana Sayfa
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Phosphatidylinositol-3-OH kinase direct target of Ras
P Rodriguez-Viciana, PH Warne, R Dhand, B Vanhaesebroeck, I Gout, ...
Nature 370 (6490), 527-532, 1994
25011994
The PI3K–PDK1 connection: more than just a road to PKB
B Vanhaesebroeck, DR Alessi
Biochemical Journal 346 (3), 561-576, 2000
20792000
Synthesis and function of 3-phosphorylated inositol lipids
B Vanhaesebroeck, SJ Leevers, K Ahmadi, J Timms, R Katso, PC Driscoll, ...
Annual review of biochemistry 70 (1), 535-602, 2001
19992001
The emerging mechanisms of isoform-specific PI3K signalling
B Vanhaesebroeck, J Guillermet-Guibert, M Graupera, B Bilanges
Nature reviews Molecular cell biology 11 (5), 329-341, 2010
15702010
Phosphoinositide 3-kinases: a conserved family of signal transducers
B Vanhaesebroeck, SJ Leevers, G Panayotou, MD Waterfield
Trends in biochemical sciences 22 (7), 267-272, 1997
12861997
Signaling by distinct classes of phosphoinositide 3-kinases
B Vanhaesebroeck, MD Waterfield
Experimental cell research 253 (1), 239-254, 1999
11481999
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation.
K Schulze-Osthoff, AC Bakker, B Vanhaesebroeck, R Beyaert, WA Jacob, ...
Journal of Biological Chemistry 267 (8), 5317-5323, 1992
10821992
Impaired B and T cell antigen receptor signaling in p110δ PI 3-kinase mutant mice
K Okkenhaug, A Bilancio, G Farjot, H Priddle, S Sancho, E Peskett, ...
Science 297 (5583), 1031-1034, 2002
10492002
Signalling through phosphoinositide 3-kinases: the lipids take centre stage
SJ Leevers, B Vanhaesebroeck, MD Waterfield
Current opinion in cell biology 11 (2), 219-225, 1999
8621999
Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
B Stoyanov, S Volinia, T Hanck, I Rubio, M Loubtchenkov, D Malek, ...
Science 269 (5224), 690-693, 1995
8621995
PI3K in lymphocyte development, differentiation and activation
K Okkenhaug, B Vanhaesebroeck
Nature Reviews Immunology 3 (4), 317-330, 2003
8422003
Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction
MP Wymann, G Bulgarelli-Leva, MJ Zvelebil, L Pirola, B Vanhaesebroeck, ...
Molecular and cellular biology 16 (4), 1722-1733, 1996
8411996
PI3K signalling: the path to discovery and understanding
B Vanhaesebroeck, L Stephens, P Hawkins
Nature reviews Molecular cell biology 13 (3), 195-203, 2012
8292012
Activation of phosphoinositide 3‐kinase by interaction with Ras and by point mutation.
P Rodriguez‐Viciana, PH Warne, B Vanhaesebroeck, MD Waterfield, ...
The EMBO journal 15 (10), 2442-2451, 1996
7501996
P110δ, a novel phosphoinositide 3-kinase in leukocytes
B Vanhaesebroeck, MJ Welham, K Kotani, R Stein, PH Warne, ...
Proceedings of the National Academy of Sciences 94 (9), 4330-4335, 1997
5491997
Signalling by PI3K isoforms: insights from gene-targeted mice
B Vanhaesebroeck, K Ali, A Bilancio, B Geering, LC Foukas
Trends in biochemical sciences 30 (4), 194-204, 2005
5352005
Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation
LC Foukas, M Claret, W Pearce, K Okkenhaug, S Meek, E Peskett, ...
Nature 441 (7091), 366-370, 2006
5232006
Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration
M Graupera, J Guillermet-Guibert, LC Foukas, LK Phng, RJ Cain, ...
Nature 453 (7195), 662-666, 2008
5092008
Essential role for the p110δ phosphoinositide 3-kinase in the allergic response
K Ali, A Bilancio, M Thomas, W Pearce, AM Gilfillan, C Tkaczyk, N Kuehn, ...
Nature 431 (7011), 1007-1011, 2004
4762004
A human phosphatidylinositol 3‐kinase complex related to the yeast Vps34p‐Vps15p protein sorting system.
S Volinia, R Dhand, B Vanhaesebroeck, LK MacDougall, R Stein, ...
The EMBO journal 14 (14), 3339-3348, 1995
4391995
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