| Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts H Gardner, JR Shearstone, R Bandaru, T Crowell, M Lynes, ... Arthritis & Rheumatism 54 (6), 1961-1973, 2006 | 198 | 2006 |
| A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU. 1 and S-phase progression R Pop, JR Shearstone, Q Shen, Y Liu, K Hallstrom, M Koulnis, J Gribnau, ... PLoS biology 8 (9), e1000484, 2010 | 194 | 2010 |
| A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies WP Kuo, F Liu, J Trimarchi, C Punzo, M Lombardi, J Sarang, ME Whipple, ... Nature biotechnology 24 (7), 832-840, 2006 | 191 | 2006 |
| Global DNA demethylation during mouse erythropoiesis in vivo JR Shearstone, R Pop, C Bock, P Boyle, A Meissner, M Socolovsky Science 334 (6057), 799-802, 2011 | 178 | 2011 |
| Identification and Analysis of Mouse Erythroid Progenitors using the CD71/TER119 Flow-cytometric Assay K Miroslav, P Ramona, P Ermelinda, S Jeffrey R, H Daniel, S Merav Journal of Visualized Experiments, 2011 | 174 | 2011 |
| Biochemical characterization of the small heat shock protein IbpB from Escherichia coli JR Shearstone, F Baneyx Journal of Biological Chemistry 274 (15), 9937, 1999 | 135 | 1999 |
| Increased levels of transforming growth factor β receptor type I and up‐regulation of matrix gene program: A model of scleroderma J Pannu, H Gardner, JR Shearstone, E Smith, M Trojanowska Arthritis & Rheumatism 54 (9), 3011-3021, 2006 | 87 | 2006 |
| AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1 S Ishigaki, SG Fonseca, CM Oslowski, A Jurczyk, JR Shearstone, LJ Zhu, ... Cell Death & Differentiation 17 (5), 774-786, 2010 | 79 | 2010 |
| TWEAK/Fn14 pathway: a nonredundant role in intestinal damage in mice through a TWEAK/intestinal epithelial cell axis T Dohi, A Borodovsky, P Wu, JR Shearstone, R Kawashima, L Runkel, ... Gastroenterology 136 (3), 912-923. e8, 2009 | 78 | 2009 |
| HDAC1, 2 inhibition impairs EZH2-and BBAP-mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma DP Johnson, GS Spitz, S Tharkar, SN Quayle, JR Shearstone, S Jones, ... Oncotarget 6 (7), 4863, 2015 | 72 | 2015 |
| Integrin β4 regulates SPARC protein to promote invasion KD Gerson, JR Shearstone, VSRK Maddula, BE Seligmann, AM Mercurio Journal of Biological Chemistry 287 (13), 9835-9844, 2012 | 63 | 2012 |
| Chemical Inhibition of Histone Deacetylases 1 and 2 Induces Fetal Hemoglobin through Activation of GATA2 JR Shearstone, O Golonzhka, A Chonkar, D Tamang, JH van Duzer, ... PLoS one 11 (4), e0153767, 2016 | 42 | 2016 |
| HDAC1, 2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute … S Tharkar-Promod, DP Johnson, SE Bennett, EM Dennis, BG Banowsky, ... Leukemia 32 (1), 49-60, 2018 | 40 | 2018 |
| Effects of β4 integrin expression on microRNA patterns in breast cancer KD Gerson, VSRK Maddula, BE Seligmann, JR Shearstone, A Khan, ... Biology Open, BIO20121628, 2012 | 36 | 2012 |
| Selective inhibitors of histone deacetylases 1 and 2 synergize with azacitidine in acute myeloid leukemia C Min, N Moore, JR Shearstone, SN Quayle, P Huang, JH van Duzer, ... PloS one 12 (1), e0169128, 2017 | 28 | 2017 |
| Nondestructive quality control for microarray production JR Shearstone, NE Allaire, ME Getman, S Perrin Biotechniques 32 (5), 1051-1057, 2002 | 24 | 2002 |
| Accurate and precise transcriptional profiles from 50 pg of total RNA or 100 flow-sorted primary lymphocytes JR Shearstone, NE Allaire, J Campos-Rivera, S Rao, S Perrin Genomics 88 (1), 111-121, 2006 | 15 | 2006 |
| Application of functional genomic technologies in a mouse model of retinal degeneration JR Shearstone, YE Wang, A Clement, NE Allaire, C Yang, DS Worley, ... Genomics 85 (3), 309-321, 2005 | 12 | 2005 |
| Mechanistic insights into fetal hemoglobin (HbF) induction through chemical inhibition of histone deacetylase 1 and 2 (HDAC1/2) JR Shearstone, JH van Duzer, SS Jones, M Jarpe Blood 122 (21), 2253, 2013 | 6 | 2013 |
| Increasing expression of interferon regulated genes with combinations of histone deacetylase inhibitors and immunomodulatory drugs SN Quayle, JR Shearstone US Patent 11,311,540, 2022 | 5 | 2022 |
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