In vivo characterization and quantification of neurofibrillary tau PET radioligand 18F-MK-6240 in humans from Alzheimer disease dementia to young controls TJ Betthauser, KA Cody, MD Zammit, D Murali, AK Converse, TE Barnhart, ... Journal of Nuclear Medicine 60 (1), 93-99, 2019 | 195 | 2019 |
Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring NJ Ashton, S Janelidze, N Mattsson-Carlgren, AP Binette, O Strandberg, ... Nature medicine 28 (12), 2555-2562, 2022 | 129 | 2022 |
Amyloid and tau imaging biomarkers explain cognitive decline from late middle-age TJ Betthauser, RL Koscik, EM Jonaitis, SL Allison, KA Cody, CM Erickson, ... Brain 143 (1), 320-335, 2020 | 129 | 2020 |
Measuring longitudinal cognition: individual tests versus composites EM Jonaitis, RL Koscik, LR Clark, Y Ma, TJ Betthauser, SE Berman, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 11, 74-84, 2019 | 107 | 2019 |
An examination of a novel multipanel of CSF biomarkers in the Alzheimer's disease clinical and pathological continuum C Van Hulle, EM Jonaitis, TJ Betthauser, R Batrla, N Wild, G Kollmorgen, ... Alzheimer's & Dementia 17 (3), 431-445, 2021 | 90 | 2021 |
The effects of normal aging on amyloid‐β deposition in nondemented adults with Down syndrome as imaged by carbon 11–labeled Pittsburgh compound B PJ Lao, TJ Betthauser, AT Hillmer, JC Price, WE Klunk, I Mihaila, ... Alzheimer's & Dementia 12 (4), 380-390, 2016 | 83 | 2016 |
Prediction of longitudinal cognitive decline in preclinical Alzheimer disease using plasma biomarkers N Mattsson-Carlgren, G Salvadó, NJ Ashton, P Tideman, E Stomrud, ... JAMA neurology 80 (4), 360-369, 2023 | 72 | 2023 |
Amyloid duration is associated with preclinical cognitive decline and tau PET RL Koscik, TJ Betthauser, EM Jonaitis, SL Allison, LR Clark, BP Hermann, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 12 (1 …, 2020 | 71 | 2020 |
In vivo comparison of tau radioligands 18F-THK-5351 and 18F-THK-5317 TJ Betthauser, PJ Lao, D Murali, TE Barnhart, S Furumoto, N Okamura, ... Journal of Nuclear Medicine 58 (6), 996-1002, 2017 | 67 | 2017 |
Longitudinal changes in amyloid positron emission tomography and volumetric magnetic resonance imaging in the nondemented Down syndrome population PJ Lao, BL Handen, TJ Betthauser, I Mihaila, SL Hartley, AD Cohen, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 9, 1-9, 2017 | 60 | 2017 |
Cerebrospinal fluid ratios with Aβ42 predict preclinical brain β‐amyloid accumulation AM Racine, RL Koscik, CR Nicholas, LR Clark, OC Okonkwo, JM Oh, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 2 (1), 27-38, 2016 | 59 | 2016 |
KLOTHO heterozygosity attenuates APOE4-related amyloid burden in preclinical AD CM Erickson, SA Schultz, JM Oh, BF Darst, Y Ma, D Norton, T Betthauser, ... Neurology 92 (16), e1878-e1889, 2019 | 58 | 2019 |
Hypertension and obesity moderate the relationship between β-amyloid and cognitive decline in midlife LR Clark, RL Koscik, SL Allison, SE Berman, D Norton, CM Carlsson, ... Alzheimer's & Dementia 15 (3), 418-428, 2019 | 51 | 2019 |
Divergent cortical tau positron emission tomography patterns among patients with preclinical Alzheimer disease CB Young, JR Winer, K Younes, KA Cody, TJ Betthauser, SC Johnson, ... JAMA neurology 79 (6), 592-603, 2022 | 35 | 2022 |
Human brain imaging of nicotinic acetylcholine α4β2* receptors using [18F]Nifene: Selectivity, functional activity, toxicity, aging effects, gender effects, and … J Mukherjee, PJ Lao, TJ Betthauser, GK Samra, ML Pan, IH Patel, C Liang, ... Journal of Comparative Neurology 526 (1), 80-95, 2018 | 35 | 2018 |
Alzheimer-like pattern of hypometabolism emerges with elevated amyloid-β burden in Down syndrome PJ Lao, BL Handen, TJ Betthauser, I Mihaila, SL Hartley, AD Cohen, ... Journal of Alzheimer's Disease 61 (2), 631-644, 2018 | 33 | 2018 |
Amyloid accumulation in Down syndrome measured with amyloid load MD Zammit, CM Laymon, TJ Betthauser, KA Cody, DL Tudorascu, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 12 (1 …, 2020 | 31 | 2020 |
The use of Centiloids for applying [11C] PiB classification cutoffs across region-of-interest delineation methods DL Tudorascu, DS Minhas, PJ Lao, TJ Betthauser, Z Yu, CM Laymon, ... Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 10, 332-339, 2018 | 31 | 2018 |
PET-BIDS, an extension to the brain imaging data structure for positron emission tomography M Norgaard, GJ Matheson, HD Hansen, A Thomas, G Searle, G Rizzo, ... Scientific data 9 (1), 65, 2022 | 29 | 2022 |
Validity evidence for the research category,“cognitively unimpaired–declining,” as a risk marker for mild cognitive impairment and Alzheimer’s disease R Langhough Koscik, BP Hermann, S Allison, LR Clark, EM Jonaitis, ... Frontiers in Aging Neuroscience 13, 688478, 2021 | 28 | 2021 |