| Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats JH Kim, LJ Bugaj, YJ Oh, TJ Bivalacqua, S Ryoo, KG Soucy, L Santhanam, ... Journal of applied physiology 107 (4), 1249-1257, 2009 | 288 | 2009 |
| Endothelial arginase II: a novel target for the treatment of atherosclerosis S Ryoo, G Gupta, A Benjo, HK Lim, A Camara, G Sikka, HK Lim, J Sohi, ... Circulation research 102 (8), 923-932, 2008 | 273 | 2008 |
| Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives MA Ilies, D Vullo, J Pastorek, A Scozzafava, M Ilies, MT Caproiu, ... Journal of medicinal chemistry 46 (11), 2187-2196, 2003 | 175 | 2003 |
| Arginase I suppresses IL-12/IL-23p40–driven intestinal inflammation during acute schistosomiasis DBR Herbert, T Orekov, A Roloson, M Ilies, C Perkins, W O’Brien, ... The Journal of immunology 184 (11), 6438-6446, 2010 | 161 | 2010 |
| Principles of self-assembly of helical pores from dendritic dipeptides V Percec, AE Dulcey, M Peterca, M Ilies, S Nummelin, MJ Sienkowska, ... Proceedings of the National Academy of Sciences 103 (8), 2518-2523, 2006 | 137 | 2006 |
| Programming the internal structure and stability of helical pores self-assembled from dendritic dipeptides via the protective groups of the peptide V Percec, AE Dulcey, M Peterca, M Ilies, MJ Sienkowska, PA Heiney Journal of the American Chemical Society 127 (50), 17902-17909, 2005 | 122 | 2005 |
| Self-assembly, structural, and retrostructural analysis of dendritic dipeptide pores undergoing reversible circular to elliptical shape change M Peterca, V Percec, AE Dulcey, S Nummelin, S Korey, M Ilies, PA Heiney Journal of the American Chemical Society 128 (20), 6713-6720, 2006 | 99 | 2006 |
| Carbonic anhydrase activators: design of high affinity isozymes I, II, and IV activators, incorporating tri-/tetrasubstituted-pyridinium-azole moieties M Ilies, MD Banciu, MA Ilies, A Scozzafava, MT Caproiu, CT Supuran Journal of medicinal chemistry 45 (2), 504-510, 2002 | 86 | 2002 |
| Carbonic anhydrase inhibitors: sulfonamides incorporating furan-, thiophene-and pyrrole-carboxamido groups possess strong topical intraocular pressure lowering properties as … M Ilies, CT Supuran, A Scozzafava, A Casini, F Mincione, L Menabuoni, ... Bioorganic & medicinal chemistry 8 (8), 2145-2155, 2000 | 84 | 2000 |
| The Internal Structure of Helical Pores Self‐Assembled from Dendritic Dipeptides is Stereochemically Programmed and Allosterically Regulated V Percec, AE Dulcey, M Peterca, M Ilies, J Ladislaw, BM Rosen, U Edlund, ... Angewandte Chemie International Edition 44 (40), 6516-6521, 2005 | 83 | 2005 |
| Inhibition of human arginase I by substrate and product analogues L Di Costanzo, M Ilies, KJ Thorn, DW Christianson Archives of biochemistry and biophysics 496 (2), 101-108, 2010 | 77 | 2010 |
| Inhibition of human arginase I by substrate and product analogues L Di Costanzo, M Ilies, KJ Thorn, DW Christianson Archives of biochemistry and biophysics 496 (2), 101-108, 2010 | 77 | 2010 |
| Binding of α, α-disubstituted amino acids to arginase suggests new avenues for inhibitor design M Ilies, L Di Costanzo, DP Dowling, KJ Thorn, DW Christianson Journal of medicinal chemistry 54 (15), 5432-5443, 2011 | 76 | 2011 |
| Binding of α, α-disubstituted amino acids to arginase suggests new avenues for inhibitor design M Ilies, L Di Costanzo, DP Dowling, KJ Thorn, DW Christianson Journal of medicinal chemistry 54 (15), 5432-5443, 2011 | 76 | 2011 |
| Carbonic anhydrase activators M Ilies, A Scozzafava, CT Supuran Carbonic anhydrase, 329-364, 2004 | 75 | 2004 |
| 2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I M Ilies, L Di Costanzo, ML North, JA Scott, DW Christianson Journal of medicinal chemistry 53 (10), 4266-4276, 2010 | 57 | 2010 |
| Helical porous protein mimics self-assembled from amphiphilic dendritic dipeptides V Percec, A Dulcey, M Peterca, M Ilies, Y Miura, U Edlund, PA Heiney Australian journal of chemistry 58 (6), 472-482, 2005 | 50 | 2005 |
| Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity X De Leval, M Ilies, A Casini, JM Dogné, A Scozzafava, E Masini, ... Journal of medicinal chemistry 47 (11), 2796-2804, 2004 | 48 | 2004 |
| Crystal Structure of Arginase from Plasmodium falciparum and Implications for l-Arginine Depletion in Malarial Infection, DP Dowling, M Ilies, KL Olszewski, S Portugal, MM Mota, M Llinás, ... Biochemistry 49 (26), 5600-5608, 2010 | 47 | 2010 |
| Protease inhibitors: synthesis of bacterial collagenase and matrix metalloproteinase inhibitors incorporating arylsulfonylureido and 5-dibenzo-suberenyl/suberyl moieties M Ilies, MD Banciu, A Scozzafava, MA Ilies, MT Caproiu, CT Supuran Bioorganic & medicinal chemistry 11 (10), 2227-2239, 2003 | 43 | 2003 |
David ChristiansonProfessor of Chemistry, University of PennsylvaniaVerified email at sas.upenn.edu
