Hacer Karatas Bristow
Hacer Karatas Bristow
Professor of Chemistry, West Virginia University
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Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia
F Cao, EC Townsend, H Karatas, J Xu, L Li, S Lee, L Liu, Y Chen, ...
Molecular cell 53 (2), 247-261, 2014
In vivo molecular bioluminescence imaging: new tools and applications
L Mezzanotte, M van‘t Root, H Karatas, EA Goun, CWGM Löwik
Trends in biotechnology 35 (7), 640-652, 2017
High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein–protein interaction
H Karatas, EC Townsend, F Cao, Y Chen, D Bernard, L Liu, M Lei, Y Dou, ...
Journal of the American Chemical Society 135 (2), 669-682, 2013
Structure-based design of high-affinity macrocyclic peptidomimetics to block the menin-mixed lineage leukemia 1 (MLL1) protein–protein interaction
H Zhou, L Liu, J Huang, D Bernard, H Karatas, A Navarro, M Lei, S Wang
Journal of Medicinal Chemistry 56 (3), 1113-1123, 2013
Discovery of a highly potent, cell-permeable macrocyclic peptidomimetic (MM-589) targeting the WD repeat domain 5 protein (WDR5)–mixed lineage leukemia (MLL) protein–protein …
H Karatas, Y Li, L Liu, J Ji, S Lee, Y Chen, J Yang, L Huang, D Bernard, ...
Journal of medicinal chemistry 60 (12), 4818-4839, 2017
Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1− WDR5 interaction
H Karatas, EC Townsend, D Bernard, Y Dou, S Wang
Journal of medicinal chemistry 53 (14), 5179-5185, 2010
MLL1 inhibition reprograms epiblast stem cells to naive pluripotency
H Zhang, S Gayen, J Xiong, B Zhou, AK Shanmugam, Y Sun, H Karatas, ...
Cell stem cell 18 (4), 481-494, 2016
Synthesis and Potent Antimicrobial Activity of Some Novel 4‐(5, 6‐Dichloro‐1H‐benzimidazol‐2‐yl)‐N‐substituted Benzamides
S Özden, H Karataş, S Yıldız, H Göker
Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2004
The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis
L Laraia, A Friese, DP Corkery, G Konstantinidis, N Erwin, W Hofer, ...
Nature chemical biology 15 (7), 710-720, 2019
TEAD–YAP Interaction Inhibitors and MDM2 Binders from DNA‐Encoded Indole‐Focused Ugi Peptidomimetics
VBK Kunig, M Potowski, M Akbarzadeh, M Klika Škopić, ...
Angewandte Chemie 132 (46), 20518-20522, 2020
BET bromodomain inhibitors and therapeutic methods using the same
S Wang, X Ran, Y Zhao, CY Yang, L Liu, L Bai, D McEachern, J Stuckey, ...
US Patent 9,675,697, 2017
MLL1 and MLL1 fusion proteins have distinct functions in regulating leukemic transcription program
J Xu, L Li, J Xiong, A DenDekker, A Ye, H Karatas, L Liu, H Wang, ZS Qin, ...
Cell discovery 2 (1), 1-11, 2016
Targeting Mll1 H3K4 methyltransferase activity to guide cardiac lineage specific reprogramming of fibroblasts
L Liu, I Lei, H Karatas, Y Li, L Wang, L Gnatovskiy, Y Dou, S Wang, L Qian, ...
Cell Discovery 2 (1), 1-11, 2016
Discovery of covalent inhibitors targeting the transcriptional enhanced associate domain central pocket
H Karatas, M Akbarzadeh, H Adihou, G Hahne, AV Pobbati, E Yihui Ng, ...
Journal of Medicinal Chemistry 63 (20), 11972-11989, 2020
A protein tertiary structure mimetic modulator of the Hippo signalling pathway
H Adihou, R Gopalakrishnan, T Förster, SM Guéret, R Gasper, ...
Nature Communications 11 (1), 5425, 2020
Identification of quinolinols as activators of TEAD-dependent transcription
AV Pobbati, T Mejuch, S Chakraborty, H Karatas, SR Bharath, SM Guéret, ...
ACS Chemical Biology 14 (12), 2909-2921, 2019
Synthesis and Potent In vitro Activity of Novel 1H‐Benzimidazoles as Anti‐MRSA Agents
H Karataş, M Alp, S Yıldız, H Göker
Chemical biology & drug design 80 (2), 237-244, 2012
Chemical suppression of specific CC chemokine signaling pathways enhances cardiac reprogramming
Y Guo, I Lei, S Tian, W Gao, K Hacer, Y Li, S Wang, L Liu, Z Wang
Journal of Biological Chemistry 294 (23), 9134-9146, 2019
The pseudo‐natural product rhonin targets RHOGDI
M Akbarzadeh, J Flegel, S Patil, E Shang, R Narayan, M Buchholzer, ...
Angewandte Chemie 134 (18), e202115193, 2022
Real-Time Imaging and Quantification of Peptide Uptake in Vitro and in Vivo
H Karatas, T Maric, PL D’Alessandro, A Yevtodiyenko, T Vorherr, ...
ACS chemical biology 14 (10), 2197-2205, 2019
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