Cinque Soto
Cinque Soto
Research Associate Professor
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Structure and immune recognition of trimeric pre-fusion HIV-1 Env
M Pancera, T Zhou, A Druz, IS Georgiev, C Soto, J Gorman, J Huang, ...
Nature 514 (7523), 455-461, 2014
Structural basis for the function and inhibition of an influenza virus proton channel
AL Stouffer, R Acharya, D Salom, AS Levine, L Di Costanzo, CS Soto, ...
Nature 451 (7178), 596-599, 2008
Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
SD Cady, K Schmidt-Rohr, J Wang, CS Soto, WF DeGrado, M Hong
Nature 463 (7281), 689-692, 2010
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
NA Doria-Rose, CA Schramm, J Gorman, PL Moore, JN Bhiman, ...
Nature 509 (7498), 55-62, 2014
Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus
JS McLellan, M Chen, MG Joyce, M Sastry, GBE Stewart-Jones, Y Yang, ...
science 342 (6158), 592-598, 2013
Evaluating conformational free energies: the colony energy and its application to the problem of loop prediction
Z Xiang, CS Soto, B Honig
Proceedings of the National Academy of Sciences 99 (11), 7432-7437, 2002
Using multiple structure alignments, fast model building, and energetic analysis in fold recognition and homology modeling
D Petrey, Z Xiang, CL Tang, L Xie, M Gimpelev, T Mitros, CS Soto, ...
Proteins: Structure, Function, and Bioinformatics 53 (S6), 430-435, 2003
Trimeric HIV-1-Env structures define glycan shields from clades A, B, and G
GBE Stewart-Jones, C Soto, T Lemmin, GY Chuang, A Druz, R Kong, ...
Cell 165 (4), 813-826, 2016
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
Y Do Kwon, M Pancera, P Acharya, IS Georgiev, ET Crooks, J Gorman, ...
Nature structural & molecular biology 22 (7), 522, 2015
Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo
RS Rudicell, Y Do Kwon, SY Ko, A Pegu, MK Louder, IS Georgiev, X Wu, ...
Journal of virology 88 (21), 12669-12682, 2014
Maturation pathway from germline to broad HIV-1 neutralizer of a CD4-mimic antibody
M Bonsignori, T Zhou, Z Sheng, L Chen, F Gao, MG Joyce, G Ozorowski, ...
Cell 165 (2), 449-463, 2016
Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors
T Zhou, RM Lynch, L Chen, P Acharya, X Wu, NA Doria-Rose, MG Joyce, ...
Cell 161 (6), 1280-1292, 2015
Maturation and diversity of the VRC01-antibody lineage over 15 years of chronic HIV-1 infection
X Wu, Z Zhang, CA Schramm, MG Joyce, Y Do Kwon, T Zhou, Z Sheng, ...
Cell 161 (3), 470-485, 2015
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
R Kong, K Xu, T Zhou, P Acharya, T Lemmin, K Liu, G Ozorowski, C Soto, ...
Science 352 (6287), 828-833, 2016
Vaccine-induced antibodies that neutralize group 1 and group 2 influenza A viruses
MG Joyce, AK Wheatley, PV Thomas, GY Chuang, C Soto, RT Bailer, ...
Cell 166 (3), 609-623, 2016
Loop modeling: Sampling, filtering, and scoring
CS Soto, M Fasnacht, J Zhu, L Forrest, B Honig
Proteins: Structure, Function, and Bioinformatics 70 (3), 834-843, 2008
Structural and dynamic mechanisms for the function and inhibition of the M2 proton channel from influenza A virus
J Wang, JX Qiu, C Soto, WF DeGrado
Current opinion in structural biology 21 (1), 68-80, 2011
Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design
J Gorman, C Soto, MM Yang, TM Davenport, M Guttman, RT Bailer, ...
Nature structural & molecular biology 23 (1), 81, 2016
De novo identification of VRC01 class HIV-1–neutralizing antibodies by next-generation sequencing of B-cell transcripts
J Zhu, X Wu, B Zhang, K McKee, S O’Dell, C Soto, T Zhou, JP Casazza, ...
Proceedings of the National Academy of Sciences 110 (43), E4088-E4097, 2013
Quantification of the impact of the HIV-1-glycan shield on antibody elicitation
T Zhou, NA Doria-Rose, C Cheng, GBE Stewart-Jones, GY Chuang, ...
Cell reports 19 (4), 719-732, 2017
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