| POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer YH Huang, O Klingbeil, XY He, XS Wu, G Arun, B Lu, TDD Somerville, ... Genes & development 32 (13-14), 915-928, 2018 | 312 | 2018 |
| Pharmacologic modulation of RNA splicing enhances anti-tumor immunity SX Lu, E De Neef, JD Thomas, E Sabio, B Rousseau, M Gigoux, DA Knorr, ... Cell 184 (15), 4032-4047. e31, 2021 | 156 | 2021 |
| LKB1, salt-inducible kinases, and MEF2C are linked dependencies in acute myeloid leukemia Y Tarumoto, B Lu, TDD Somerville, YH Huang, JP Milazzo, XS Wu, ... Molecular cell 69 (6), 1017-1027. e6, 2018 | 131 | 2018 |
| ATRX loss induces telomere dysfunction and necessitates induction of alternative lengthening of telomeres during human cell immortalization F Li, Z Deng, L Zhang, C Wu, Y Jin, I Hwang, O Vladimirova, L Xu, L Yang, ... The EMBO journal 38 (19), e96659, 2019 | 85 | 2019 |
| Displacement of WDR5 from chromatin by a WIN site inhibitor with picomolar affinity ER Aho, J Wang, RD Gogliotti, GC Howard, J Phan, P Acharya, ... Cell reports 26 (11), 2916-2928. e13, 2019 | 82 | 2019 |
| A transcription factor addiction in leukemia imposed by the MLL promoter sequence B Lu, O Klingbeil, Y Tarumoto, TDD Somerville, YH Huang, Y Wei, ... Cancer Cell 34 (6), 970-981. e8, 2018 | 55 | 2018 |
| MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity A Skucha, J Ebner, J Schmöllerl, M Roth, T Eder, A César-Razquin, ... Nature Communications 9 (1), 1983, 2018 | 52 | 2018 |
| The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators DCC Wai, TN Szyszka, AE Campbell, C Kwong, LE Wilkinson-White, ... Journal of Biological Chemistry 293 (19), 7160-7175, 2018 | 50 | 2018 |
| Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo Y Tarumoto, S Lin, J Wang, JP Milazzo, Y Xu, B Lu, Z Yang, Y Wei, ... Blood, The Journal of the American Society of Hematology 135 (1), 56-70, 2020 | 48 | 2020 |
| ANP32A regulates histone H3 acetylation and promotes leukemogenesis X Yang, B Lu, X Sun, C Han, C Fu, K Xu, M Wang, D Li, Z Chen, P Opal, ... Leukemia 32 (7), 1587-1597, 2018 | 39 | 2018 |
| ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency Z Cao, KA Budinich, H Huang, D Ren, B Lu, Z Zhang, Q Chen, Y Zhou, ... Molecular cell 81 (17), 3604-3622. e10, 2021 | 37 | 2021 |
| Enhancer dysfunction in leukemia AS Bhagwat, B Lu, CR Vakoc Blood, The Journal of the American Society of Hematology 131 (16), 1795-1804, 2018 | 35 | 2018 |
| Induction of INKIT by viral infection negatively regulates antiviral responses through inhibiting phosphorylation of p65 and IRF3 B Lu, Y Ren, X Sun, C Han, H Wang, Y Chen, Q Peng, Y Cheng, X Cheng, ... Cell host & microbe 22 (1), 86-98. e4, 2017 | 34 | 2017 |
| Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling X Sun, B Lu, B Hu, W Xiao, W Li, Z Huang Blood Cancer Journal 4 (3), e198-e198, 2014 | 26 | 2014 |
| BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network X Sun, O Klingbeil, B Lu, C Wu, C Ballon, M Ouyang, XS Wu, Y Jin, ... Nature 613 (7942), 195-202, 2023 | 21 | 2023 |
| Impaired proteolysis of noncanonical RAS proteins drives clonal hematopoietic transformation S Chen, RS Vedula, A Cuevas-Navarro, B Lu, SJ Hogg, E Wang, ... Cancer discovery 12 (10), 2434-2453, 2022 | 16 | 2022 |
| Novel function of PITH domain-containing 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation B Lu, X Sun, Y Chen, Q Jin, Q Liang, S Liu, Y Li, Y Zhou, W Li, Z Huang Cellular and molecular life sciences 72, 821-832, 2015 | 15 | 2015 |
| ANP32A dysregulation contributes to abnormal megakaryopoiesis in acute megakaryoblastic leukemia X Sun, B Lu, C Han, W Qiu, Q Jin, D Li, Q Li, Q Yang, Q Wen, P Opal, ... Blood cancer journal 7 (12), 661, 2017 | 14 | 2017 |
| Promoting spliceosome assembly for therapeutic intent B Lu, O Abdel-Wahab Trends in Pharmacological Sciences 42 (12), 981-983, 2021 | 3 | 2021 |
| SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia SA Polyanskaya, RY Moreno, B Lu, R Feng, Y Yao, S Irani, O Klingbeil, ... Cell reports 38 (2), 2022 | 2 | 2022 |
