Multiplex genome engineering using CRISPR/Cas systems L Cong, FA Ran, D Cox, S Lin, R Barretto, N Habib, PD Hsu, X Wu, ... Science 339 (6121), 819-823, 2013 | 17965 | 2013 |
RNA-guided editing of bacterial genomes using CRISPR-Cas systems W Jiang, D Bikard, D Cox, F Zhang, LA Marraffini Nature biotechnology 31 (3), 233-239, 2013 | 3014 | 2013 |
Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system D Bikard, W Jiang, P Samai, A Hochschild, F Zhang, LA Marraffini Nucleic acids research 41 (15), 7429-7437, 2013 | 1363 | 2013 |
Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials D Bikard, CW Euler, W Jiang, PM Nussenzweig, GW Goldberg, X Duportet, ... Nature biotechnology 32 (11), 1146-1150, 2014 | 926 | 2014 |
Co-transcriptional DNA and RNA cleavage during type III CRISPR-Cas immunity P Samai, N Pyenson, W Jiang, GW Goldberg, A Hatoum-Aslan, ... Cell 161 (5), 1164-1174, 2015 | 475 | 2015 |
Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting GW Goldberg, W Jiang, D Bikard, LA Marraffini Nature 514 (7524), 633-637, 2014 | 298 | 2014 |
Crispr-cas component systems, methods and compositions for sequence manipulation F Zhang, L Cong, DBT Cox, P Hsu, LIN Shuailiang, RAN Fei, RJ Platt, ... US Patent App. 14/105,035, 2014 | 273 | 2014 |
Dealing with the evolutionary downside of CRISPR immunity: bacteria and beneficial plasmids W Jiang, I Maniv, F Arain, Y Wang, BR Levin, LA Marraffini PLoS genetics 9 (9), e1003844, 2013 | 251 | 2013 |
CRISPR-Cas: new tools for genetic manipulations from bacterial immunity systems W Jiang, LA Marraffini Annual review of microbiology 69, 209-228, 2015 | 236 | 2015 |
Degradation of phage transcripts by CRISPR-associated RNases enables type III CRISPR-Cas immunity W Jiang, P Samai, LA Marraffini Cell 164 (4), 710-721, 2016 | 225 | 2016 |
Crispr-cas component systems, methods and compositions for sequence manipulation F Zhang, DBT Cox, L Marraffini, DO Bikard, W Jiang US Patent App. 14/497,627, 2015 | 223 | 2015 |
Crispr-cas component systems, methods and compositions for sequence manipulation F Zhang, DO BIKARD, L Cong, DBT Cox, P Hsu, W Jiang, LIN Shauiliang, ... | 221 | 2014 |
CRISPR–Cas systems exploit viral DNA injection to establish and maintain adaptive immunity JW Modell, W Jiang, LA Marraffini Nature 544 (7648), 101-104, 2017 | 154 | 2017 |
Prokaryotic single-cell RNA sequencing by in situ combinatorial indexing SB Blattman, W Jiang, P Oikonomou, S Tavazoie Nature microbiology 5 (10), 1192-1201, 2020 | 136 | 2020 |
A ruler protein in a complex for antiviral defense determines the length of small interfering CRISPR RNAs A Hatoum-Aslan, P Samai, I Maniv, W Jiang, LA Marraffini Journal of Biological Chemistry 288 (39), 27888-27897, 2013 | 135 | 2013 |
Crispr-cas component systems, methods and compositions for sequence manipulation F Zhang, DBT Cox, L Marraffini, DO Bikard, W Jiang, NE Sanjana US Patent App. 15/887,377, 2018 | 128 | 2018 |
CRISPR-assisted editing of bacterial genomes W Jiang, D Bikard, D Cox, F Zhang, LA Marraffini Nature biotechnology 31 (3), 233, 2013 | 124 | 2013 |
Development of sequence-specific antimicrobials based on programmable CRISPR-Cas nucleases D Bikard, C Euler, W Jiang, PM Nussenzweig, GW Goldberg, X Duportet, ... Nature biotechnology 32 (11), 1146, 2014 | 64 | 2014 |
Impact of different target sequences on type III CRISPR-Cas immunity I Maniv, W Jiang, D Bikard, LA Marraffini Journal of bacteriology 198 (6), 941-950, 2016 | 55 | 2016 |
Incomplete prophage tolerance by type III-A CRISPR-Cas systems reduces the fitness of lysogenic hosts GW Goldberg, EA McMillan, A Varble, JW Modell, P Samai, W Jiang, ... Nature communications 9 (1), 61, 2018 | 41 | 2018 |