Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway RE Haskew-Layton, JB Payappilly, NA Smirnova, TC Ma, KK Chan, ... Proceedings of the National Academy of Sciences 107 (40), 17385-17390, 2010 | 163 | 2010 |
Development of Neh2-luciferase reporter and its application for high throughput screening and real-time monitoring of Nrf2 activators NA Smirnova, RE Haskew-Layton, M Basso, DM Hushpulian, ... Chemistry & biology 18 (6), 752-765, 2011 | 134 | 2011 |
Harnessing hypoxic adaptation to prevent, treat, and repair stroke RR Ratan, A Siddiq, N Smirnova, K Karpisheva, R Haskew-Layton, ... Journal of Molecular Medicine 85, 1331-1338, 2007 | 115 | 2007 |
Recent advances in hydrogen peroxide imaging for biological applications H Guo, H Aleyasin, BC Dickinson, RE Haskew-Layton, RR Ratan Cell & bioscience 4, 1-10, 2014 | 110 | 2014 |
CD36 is involved in astrocyte activation and astroglial scar formation Y Bao, L Qin, E Kim, S Bhosle, H Guo, M Febbraio, RE Haskew-Layton, ... Journal of Cerebral Blood Flow & Metabolism 32 (8), 1567-1577, 2012 | 107 | 2012 |
Sedative and anxiolytic effects of zopiclone's enantiomers and metabolite JN Carlson, R Haskew, J Wacker, IM Maisonneuve, SD Glick, TP Jerussi European journal of pharmacology 415 (2-3), 181-189, 2001 | 93 | 2001 |
Enantioselective behavioral effects of sibutramine metabolites SD Glick, RE Haskew, IM Maisonneuve, JN Carlson, TP Jerussi European journal of pharmacology 397 (1), 93-102, 2000 | 82 | 2000 |
Two distinct modes of hypoosmotic medium-induced release of excitatory amino acids and taurine in the rat brain in vivo RE Haskew-Layton, A Rudkouskaya, Y Jin, PJ Feustel, HK Kimelberg, ... PloS one 3 (10), e3543, 2008 | 79 | 2008 |
Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation M Basso, J Berlin, L Xia, SF Sleiman, B Ko, R Haskew-Layton, E Kim, ... Journal of Neuroscience 32 (19), 6561-6569, 2012 | 77 | 2012 |
Hydrogen peroxide potentiates volume-sensitive excitatory amino acid release via a mechanism involving Ca2+/calmodulin-dependent protein kinase II RE Haskew-Layton, AA Mongin, HK Kimelberg Journal of Biological Chemistry 280 (5), 3548-3554, 2005 | 57 | 2005 |
Two conventional protein kinase C isoforms, α and βI, are involved in the ATP‐induced activation of volume‐regulated anion channel and glutamate release in cultured astrocytes A Rudkouskaya, A Chernoguz, RE Haskew‐Layton, AA Mongin Journal of neurochemistry 105 (6), 2260-2270, 2008 | 52 | 2008 |
15‐Deoxy‐Δ12, 14‐prostaglandin J2 (15d‐PGJ 2) protects neurons from oxidative death via an Nrf2 astrocyte‐specific mechanism independent of PPAR γ RE Haskew‐Layton, JB Payappilly, H Xu, SAL Bennett, RR Ratan Journal of neurochemistry 124 (4), 536-547, 2013 | 49 | 2013 |
Peroxynitrite enhances astrocytic volume‐sensitive excitatory amino acid release via a src tyrosine kinase‐dependent mechanism RE Haskew, AA Mongin, HK Kimelberg Journal of neurochemistry 82 (4), 903-912, 2002 | 49 | 2002 |
Iboga compounds reverse the behavioural disinhibiting and corticosterone effects of acute methamphetamine: Implications for their antiaddictive properties KK Szumlinski, RE Haskew, MY Balogun, IM Maisonneuve, SD Glick Pharmacology Biochemistry and Behavior 69 (3-4), 485-491, 2001 | 36 | 2001 |
Hypo‐osmotic swelling modifies glutamate‐glutamine cycle in the cerebral cortex and in astrocyte cultures MC Hyzinski‐García, MY Vincent, RE Haskew‐Layton, P Dohare, ... Journal of neurochemistry 118 (1), 140-152, 2011 | 33 | 2011 |
Antihelminthic Benzimidazoles Are Novel HIF Activators That Prevent Oxidative Neuronal Death via Binding to Tubulin H Aleyasin, SS Karuppagounder, A Kumar, S Sleiman, M Basso, T Ma, ... Antioxidants & redox signaling 22 (2), 121-134, 2015 | 25 | 2015 |
Two-photon fluorescence imaging of intracellular hydrogen peroxide with chemoselective fluorescent probes H Guo, H Aleyasin, SS Howard, BC Dickinson, VS Lin, ... Journal of Biomedical Optics 18 (10), 106002-106002, 2013 | 21 | 2013 |
Spatial, temporal, and quantitative manipulation of intracellular hydrogen peroxide in cultured cells I Alim, RE Haskew-Layton, H Aleyasin, H Guo, RR Ratan Methods in enzymology 547, 251-273, 2014 | 14 | 2014 |
Two conventional PKC isoforms, α and βI, are involved in the ATP-induced regulation of VRAC and glutamate release in cultured astrocytes A Rudkouskaya, A Chernoguz, RE Haskew-Layton, AA Mongin Journal of neurochemistry 105 (6), 2008 | 6 | 2008 |
Chick embryonic primary astrocyte cultures provide an effective and scalable model for authentic research in a laboratory class RE Haskew-Layton, JR Minkler Journal of Undergraduate Neuroscience Education 18 (2), A86, 2020 | 5 | 2020 |