|Targeting transcription factor NF-κB to overcome chemoresistance and radioresistance in cancer therapy|
F Li, G Sethi
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1805 (2), 167-180, 2010
|Potential role of signal transducer and activator of transcription (STAT) 3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma|
A Subramaniam, MK Shanmugam, E Perumal, F Li, A Nachiyappan, X Dai, ...
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1835 (1), 46-60, 2013
|Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription …|
F Li, P Rajendran, G Sethi
British journal of pharmacology 161 (3), 541-554, 2010
|Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells|
F Li, PP Fernandez, P Rajendran, KM Hui, G Sethi
Cancer letters 292 (2), 197-207, 2010
|NF-κB in cancer therapy|
F Li, J Zhang, F Arfuso, A Chinnathambi, ME Zayed, SA Alharbi, ...
Archives of toxicology 89 (5), 711-731, 2015
|Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways|
R Kannaiyan, KA Manu, L Chen, F Li, P Rajendran, A Subramaniam, ...
Apoptosis 16 (10), 1028-1041, 2011
|Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo|
P Rajendran, F Li, MK Shanmugam, R Kannaiyan, JN Goh, KF Wong, ...
Cancer prevention research 5 (4), 631-643, 2012
|Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice|
MK Shanmugam, P Rajendran, F Li, T Nema, S Vali, T Abbasi, S Kapoor, ...
Journal of molecular medicine 89 (7), 713-727, 2011
|Celastrol inhibits proliferation and induces chemosensitization through down‐regulation of NF‐κB and STAT3 regulated gene products in multiple myeloma cells|
R Kannaiyan, HS Hay, P Rajendran, F Li, MK Shanmugam, S Vali, ...
British journal of pharmacology 164 (5), 1506-1521, 2011
|Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse …|
KS Siveen, N Mustafa, F Li, R Kannaiyan, KS Ahn, AP Kumar, WJ Chng, ...
Oncotarget 5 (3), 634, 2014
|Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo|
G Sethi, S Chatterjee, P Rajendran, F Li, MK Shanmugam, KF Wong, ...
Molecular cancer 13 (1), 1-14, 2014
|Honokiol inhibits signal transducer and activator of transcription‐3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine …|
P Rajendran, F Li, MK Shanmugam, S Vali, T Abbasi, S Kapoor, KS Ahn, ...
Journal of cellular physiology 227 (5), 2184-2195, 2012
|Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3|
A Subramaniam, MK Shanmugam, TH Ong, F Li, E Perumal, L Chen, ...
British journal of pharmacology 170 (4), 807-821, 2013
|Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4|
KA Manu, MK Shanmugam, P Rajendran, F Li, L Ramachandran, HS Hay, ...
Molecular cancer 10 (1), 1-14, 2011
|Suppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivo|
P Rajendran, TH Ong, L Chen, F Li, MK Shanmugam, S Vali, T Abbasi, ...
Clinical cancer research 17 (6), 1425-1439, 2011
|Identification of β-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation …|
SML Tan, F Li, P Rajendran, AP Kumar, KM Hui, G Sethi
Journal of Pharmacology and Experimental Therapeutics 334 (1), 285-293, 2010
|γ‐Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro …|
P Rajendran, F Li, KA Manu, MK Shanmugam, SY Loo, AP Kumar, ...
British journal of pharmacology 163 (2), 283-298, 2011
|Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer|
L Ramachandran, KA Manu, MK Shanmugam, F Li, KS Siveen, S Vali, ...
Journal of Biological Chemistry 287 (45), 38028-38040, 2012
|First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB …|
KA Manu, MK Shanmugam, L Ramachandran, F Li, CW Fong, AP Kumar, ...
Clinical Cancer Research 18 (8), 2220-2229, 2012
|Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells|
AWL Chua, HS Hay, P Rajendran, MK Shanmugam, F Li, P Bist, ...
Biochemical pharmacology 80 (10), 1553-1562, 2010