Alexander Mankin
Alexander Mankin
University of Illinois at Chicagp
Verified email at uic.edu
Title
Cited by
Cited by
Year
Acquisition of a natural resistance gene renders a clinical strain of methicillin‐resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid
SM Toh, L Xiong, CA Arias, MV Villegas, K Lolans, J Quinn, AS Mankin
Molecular microbiology 64 (6), 1506-1514, 2007
3432007
Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action
JA Dunkle, L Xiong, AS Mankin, JHD Cate
Proceedings of the National Academy of Sciences 107 (40), 17152-17157, 2010
3222010
Resistance mutations in 23 S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center
P Kloss, L Xiong, DL Shinabarger, AS Mankin
Journal of molecular biology 294 (1), 93-101, 1999
2411999
The site of action of oxazolidinone antibiotics in living bacteria and in human mitochondria
KL Leach, SM Swaney, JR Colca, WG McDonald, JR Blinn, LM Thomasco, ...
Molecular cell 26 (3), 393-402, 2007
2362007
Macrolide antibiotics: binding site, mechanism of action, resistance
M Gaynor, AS Mankin
Current topics in medicinal chemistry 3 (9), 949-960, 2003
2292003
Molecular mechanism of drug-dependent ribosome stalling
N Vazquez-Laslop, C Thum, AS Mankin
Molecular cell 30 (2), 190-202, 2008
2272008
Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide
N Polacek, M Gaynor, A Yassin, AS Mankin
Nature 411 (6836), 498-501, 2001
2052001
Oxazolidinone Resistance Mutations in 23S rRNA ofEscherichia coli Reveal the Central Region of Domain V as the Primary Site of Drug Action
L Xiong, P Kloss, S Douthwaite, NM Andersen, S Swaney, ...
Journal of bacteriology 182 (19), 5325-5331, 2000
1972000
Antibiotics and the ribosome
T Tenson, A Mankin
Molecular microbiology 59 (6), 1664-1677, 2006
1882006
A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre
L Xiong, S Shah, P Mauvais, AS Mankin
Molecular microbiology 31 (2), 633-639, 1999
1831999
The ribosomal peptidyl transferase center: structure, function, evolution, inhibition
N Polacek, AS Mankin
Critical reviews in biochemistry and molecular biology 40 (5), 285-311, 2005
1812005
Cross-linking in the living cell locates the site of action of oxazolidinone antibiotics
JR Colca, WG McDonald, DJ Waldon, LM Thomasco, RC Gadwood, ...
Journal of Biological Chemistry 278 (24), 21972-21979, 2003
1702003
Nucleotide biosynthesis is critical for growth of bacteria in human blood
S Samant, H Lee, M Ghassemi, J Chen, JL Cook, AS Mankin, AA Neyfakh
PLoS Pathog 4 (2), e37, 2008
1692008
Programmed drug‐dependent ribosome stalling
H Ramu, A Mankin, N Vazquez‐Laslop
Molecular microbiology 71 (4), 811-824, 2009
1532009
Identification of ten additional nucleotides in the primary structure of yeast 18S rRNA
AS Mankin, KG Skryabin, PM Rubtsov
Gene 44 (1), 143-145, 1986
1531986
RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA
F Yan, JM LaMarre, R Röhrich, J Wiesner, H Jomaa, AS Mankin, ...
Journal of the American Chemical Society 132 (11), 3953-3964, 2010
1462010
Protein synthesis by ribosomes with tethered subunits
C Orelle, ED Carlson, T Szal, T Florin, MC Jewett, AS Mankin
Nature 524 (7563), 119-124, 2015
1442015
The antibiotic thiostrepton inhibits a functional transition within protein L11 at the ribosomal GTPase centre
BT Porse, I Leviev, AS Mankin, RA Garrett
Journal of molecular biology 276 (2), 391-404, 1998
1441998
Binding site of macrolide antibiotics on the ribosome: new resistance mutation identifies a specific interaction of ketolides with rRNA
G Garza-Ramos, L Xiong, P Zhong, A Mankin
Journal of Bacteriology 183 (23), 6898-6907, 2001
1432001
Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis
B Llano-Sotelo, J Dunkle, D Klepacki, W Zhang, P Fernandes, JHD Cate, ...
Antimicrobial agents and chemotherapy 54 (12), 4961-4970, 2010
1302010
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