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Leila Dorling
Leila Dorling
Centre for Cancer Genetic Epidemiology, University of Cambridge
Verified email at medschl.cam.ac.uk
Title
Cited by
Cited by
Year
Breast cancer risk genes—association analysis in more than 113,000 women
Breast Cancer Association Consortium
New England Journal of Medicine 384 (5), 428-439, 2021
7672021
Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families
X Yang, G Leslie, A Doroszuk, S Schneider, J Allen, B Decker, ...
Journal of clinical oncology 38 (7), 674-685, 2020
4112020
Randomized controlled trial of intensity-modulated radiotherapy for early breast cancer: 5-year results confirm superior overall cosmesis
MB Mukesh, GC Barnett, JS Wilkinson, AM Moody, C Wilson, L Dorling, ...
Journal of clinical oncology 31 (36), 4488-4495, 2013
2542013
A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity
GC Barnett, D Thompson, L Fachal, S Kerns, C Talbot, RM Elliott, ...
Radiotherapy and Oncology 111 (2), 178-185, 2014
1842014
A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24. 1
L Fachal, A Gomez-Caamano, GC Barnett, P Peleteiro, AM Carballo, ...
Nature genetics 46 (8), 891-894, 2014
1692014
Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients
CN Andreassen, BS Rosenstein, SL Kerns, H Ostrer, D De Ruysscher, ...
Radiotherapy and Oncology 121 (3), 431-439, 2016
1302016
Replication of genetic polymorphisms reported to be associated with taxane-related sensory neuropathy in patients with early breast cancer treated with Paclitaxel
JE Abraham, Q Guo, L Dorling, J Tyrer, S Ingle, R Hardy, AL Vallier, ...
Clinical Cancer Research 20 (9), 2466-2475, 2014
1232014
Radiogenomics consortium genome-wide association study meta-analysis of late toxicity after prostate cancer radiotherapy
SL Kerns, L Fachal, L Dorling, GC Barnett, A Baran, DR Peterson, ...
JNCI: Journal of the National Cancer Institute 112 (2), 179-190, 2020
972020
Meta-analysis of genome wide association studies identifies genetic markers of late toxicity following radiotherapy for prostate cancer
SL Kerns, L Dorling, L Fachal, S Bentzen, PDP Pharoah, DR Barnes, ...
EBioMedicine 10, 150-163, 2016
922016
Pathology of tumors associated with pathogenic germline variants in 9 breast cancer susceptibility genes
N Mavaddat, L Dorling, S Carvalho, J Allen, A Gonzalez-Neira, R Keeman, ...
JAMA oncology 8 (3), e216744-e216744, 2022
822022
Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study
X Yang, M Eriksson, K Czene, A Lee, G Leslie, M Lush, J Wang, J Dennis, ...
Journal of medical genetics 59 (12), 1196-1205, 2022
522022
Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort
J Li, WX Wen, M Eklund, A Kvist, M Eriksson, HN Christensen, ...
International journal of cancer 144 (5), 1195-1204, 2019
492019
Patient reported outcome measures (PROMs) following forward planned field-in field IMRT: results from the Cambridge Breast IMRT trial
MB Mukesh, W Qian, JS Wilkinson, L Dorling, GC Barnett, AM Moody, ...
Radiotherapy and Oncology 111 (2), 270-275, 2014
472014
Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia
WX Wen, J Allen, KN Lai, S Mariapun, SN Hasan, PS Ng, DSC Lee, ...
Journal of medical genetics 55 (2), 97-103, 2018
452018
A nested cohort study of 6,248 early breast cancer patients treated in neoadjuvant and adjuvant chemotherapy trials investigating the prognostic value of chemotherapy-related …
JE Abraham, L Hiller, L Dorling, AL Vallier, J Dunn, S Bowden, S Ingle, ...
BMC medicine 13, 1-9, 2015
382015
Breast cancer risks associated with missense variants in breast cancer susceptibility genes
L Dorling, S Carvalho, J Allen, MT Parsons, C Fortuno, A González-Neira, ...
Genome medicine 14 (1), 51, 2022
352022
Differential burden of rare and common variants on tumor characteristics, survival, and mode of detection in breast cancer
J Li, E Ugalde-Morales, WX Wen, B Decker, M Eriksson, A Torstensson, ...
Cancer Research 78 (21), 6329-6338, 2018
282018
Patients with a high polygenic risk of breast cancer do not have an increased risk of radiotherapy toxicity
L Dorling, GC Barnett, K Michailidou, CE Coles, NG Burnet, J Yarnold, ...
Clinical Cancer Research 22 (6), 1413-1420, 2016
252016
Splicing predictions, minigene analyses, and ACMG‐AMP clinical classification of 42 germline PALB2 splice‐site variants
A Valenzuela‐Palomo, E Bueno‐Martínez, L Sanoguera‐Miralles, ...
The Journal of Pathology 256 (3), 321-334, 2022
222022
Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity
M Ahmed, L Dorling, S Kerns, L Fachal, R Elliott, M Partliament, ...
British Journal of Cancer 114 (10), 1165-1174, 2016
192016
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