| Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq B Wienert, SK Wyman, CD Richardson, CD Yeh, P Akcakaya, MJ Porritt, ... Science 364 (6437), 286-289, 2019 | 350 | 2019 |
| In vivo CRISPR editing with no detectable genome-wide off-target mutations P Akcakaya, ML Bobbin, JA Guo, J Malagon-Lopez, K Clement, SP Garcia, ... Nature 561 (7723), 416-419, 2018 | 331 | 2018 |
| The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma DM Özata, S Caramuta, D Velazquez-Fernandez, P Akçakaya, H Xie, ... Endocrine-related cancer 18 (6), 643-655, 2011 | 215 | 2011 |
| miR-185 and miR-133b deregulation is associated with overall survival and metastasis in colorectal cancer P Akcakaya, S Ekelund, I Kolosenko, S Caramuta, DM Özata, H Xie, ... International journal of oncology 39 (2), 311-318, 2011 | 188 | 2011 |
| Serum microRNA expression in pregnancies with preeclampsia T Gunel, YG Zeybek, P Akçakaya, I Kalelioglu, A Benian, H Ermis, ... Genet Mol Res 10 (4), 4034-4040, 2011 | 123 | 2011 |
| In vivo genome and base editing of a human PCSK9 knock-in hypercholesterolemic mouse model A Carreras, LS Pane, R Nitsch, K Madeyski-Bengtson, M Porritt, ... BMC biology 17, 1-14, 2019 | 81 | 2019 |
| Role of microRNAs and microRNA machinery in the pathogenesis of diffuse large B-cell lymphoma S Caramuta, L Lee, DM Özata, P Akçakaya, P Georgii-Hemming, H Xie, ... Blood cancer journal 3 (10), e152-e152, 2013 | 72 | 2013 |
| Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma S Caramuta, L Lee, DM Özata, P Akçakaya, H Xie, A Höög, J Zedenius, ... Endocrine-related cancer 20 (4), 551-564, 2013 | 70 | 2013 |
| Functional role of the Ca2+-activated Cl− channel DOG1/TMEM16A in gastrointestinal stromal tumor cells E Berglund, P Akcakaya, D Berglund, F Karlsson, V Vukojević, L Lee, ... Experimental cell research 326 (2), 315-325, 2014 | 63 | 2014 |
| Adenomatous polyposis coli-mediated control of β-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors RL Miclea, M Karperien, CAJ Bosch, G van der Horst, MA van der Valk, ... BMC developmental biology 9, 1-14, 2009 | 62 | 2009 |
| microRNA expression signatures of gastrointestinal stromal tumours: associations with imatinib resistance and patient outcome P Akcakaya, S Caramuta, J Åhlen, M Ghaderi, E Berglund, A Östman, ... British journal of cancer 111 (11), 2091-2102, 2014 | 56 | 2014 |
| miR-125a-5p regulation increases phosphorylation of FAK that contributes to imatinib resistance in gastrointestinal stromal tumors WK Huang, P Akçakaya, A Gangaev, L Lee, K Zeljic, P Hajeri, E Berglund, ... Experimental cell research 371 (1), 287-296, 2018 | 31 | 2018 |
| Intracellular concentration of the tyrosine kinase inhibitor imatinib in gastrointestinal stromal tumor cells E Berglund, SJKA Ubhayasekera, F Karlsson, P Akcakaya, ... Anti-Cancer Drugs 25 (4), 415-422, 2014 | 19 | 2014 |
| Evidence for Ca2+-regulated ATP release in gastrointestinal stromal tumors E Berglund, D Berglund, P Akcakaya, M Ghaderi, E Daré, PO Berggren, ... Experimental cell research 319 (8), 1229-1238, 2013 | 15 | 2013 |
| Simultaneous inhibition of DNA-PK and Polϴ improves integration efficiency and precision of genome editing S Wimberger, N Akrap, M Firth, J Brengdahl, S Engberg, MK Schwinn, ... Nature Communications 14 (1), 4761, 2023 | 14 | 2023 |
| Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes M Zabulica, RC Srinivasan, P Akcakaya, G Allegri, B Bestas, M Firth, ... Molecular Therapy 29 (5), 1903-1917, 2021 | 14 | 2021 |
| The functional SLC11A1 gene polymorphisms are associated with sarcoidosis in Turkish population P Akçakaya, B Azeroglu, I Even, O Ates, H Turker, G Ongen, ... Molecular biology reports 39, 5009-5016, 2012 | 10 | 2012 |
| Imatinib Regulates miR-483-3p and Mitochondrial Respiratory Complexes in Gastrointestinal Stromal Tumors WK Huang, H Shi, P Akçakaya, K Zeljic, A Gangaev, S Caramuta, CN Yeh, ... International Journal of Molecular Sciences 22 (19), 10600, 2021 | 9 | 2021 |
| Negative DNA supercoiling induces genome-wide Cas9 off-target activity MD Newton, M Losito, QM Smith, N Parnandi, BJ Taylor, P Akcakaya, ... Molecular Cell 83 (19), 3533-3545. e5, 2023 | 8 | 2023 |
| Secretome protein signature of human gastrointestinal stromal tumor cells E Berglund, E Dare, RMM Branca, P Akcakaya, R Fröbom, PO Berggren, ... Experimental cell research 336 (1), 158-170, 2015 | 7 | 2015 |
